Results of the Schirmer tear test performed with open and closed eyes in clinically normal horses.
Abstract: The Schirmer tear test (STT) is widely used in both human and veterinary ophthalmology. Two types of STTs have been developed: STT I and SST II. The STT I measures the basal and reflex tear production and is the most widely used STT. However, several factors influence the STT results such as the person performing the test and the location of the strip placement within the conjunctival sac. The aim of this study was to measure the basal and reflex tear production (STT I) in clinically normal horses with open versus closed eyes. Results: Forty clinically healthy horses without any ocular diseases were included. On day 1, the STT I was first performed on all the horses with the eyes open followed by an STT I with closed eyes performed 30 min later. On day 2, all horses had their eyes closed during the first STT and the eyes open during the second test performed 30 min later. The mean value of the STTs performed on open eye was significantly less than the STT performed on closed eye on both days of examination. Conclusions: This study showed a small but statistically significant difference between STT values obtained with open versus closed eyes in clinically normal horses.
Publication Date: 2017-05-31 PubMed ID: 28569172PubMed Central: PMC5452394DOI: 10.1186/s13028-017-0303-2Google Scholar: Lookup
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- Journal Article
- Observational Study
Summary
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The paper studies the difference in tear production in healthy horses in the context of the Schirmer tear test (STT), comparing results from the test with the eyes open versus closed. It concludes there is a small but significant variation in values obtained by these two methods.
Background of the Study
- The Schirmer tear test (STT) is a standard procedure utilized both in human and veterinary ophthalmology. This research focuses on its application in horses.
- STT is used to measure tear production, vital for maintaining eye health. Two kinds of STTs have been identified: STT I (which assesses basal and reflex tear production and is more commonly used) and STT II.
- The study acknowledges that varying factors can affect the results of the STT, including the individual conducting the test and the placement of the strip within the conjunctival sac.
Objective and Methodology
- The research aimed to measure and compare the results of the STT I in clinically healthy horses with open and closed eyes.
- The study encompassed forty clinically healthy horses with no ocular diseases.
- On the first day, the participants underwent the STT I with their eyes open, followed by a second STT I 30 minutes later with their eyes closed.
- On the second day, the process was reversed; the horses’ eyes were closed for the first STT and open for the second test.
Findings and Conclusion
- The mean value of the STTs performed on open eyes was considerably lower than that of the STTs taken on closed eyes on both days of examination.
- The study concluded that while the difference was small, it was statistically significant in differentiating STT values obtained with open versus closed eyes in clinically normal horses.
Cite This Article
APA
Trbolova A, Ghaffari MS.
(2017).
Results of the Schirmer tear test performed with open and closed eyes in clinically normal horses.
Acta Vet Scand, 59(1), 35.
https://doi.org/10.1186/s13028-017-0303-2 Publication
Researcher Affiliations
- Clinic of Small Animals, University of Veterinary Medicine and Pharmacy, Kosice, Slovakia.
- Department of Clinical Sciences, College of Veterinary Medicine, Karaj Branch, Islamic Azad University, Alborz, Iran. selkghaffari@gmail.com.
MeSH Terms
- Animals
- Blinking / physiology
- Diagnostic Techniques, Ophthalmological / veterinary
- Female
- Horses / physiology
- Male
- Reference Values
- Tears / metabolism
References
This article includes 19 references
- Ofri R, Horowitz IH, Raz D, Shvartsman E, Kass PH. Intraocular pressure and tear production in five herbivorous wildlife species.. Vet Rec 2002 Aug 31;151(9):265-8.
- Williams DL. Analysis of tear uptake by the Schirmer tear test strip in the canine eye.. Vet Ophthalmol 2005 Sep-Oct;8(5):325-30.
- Rothschild CM, Sellon DC, Bryan GM, Gay JM, Hines MT. Effects of trimethoprim-sulfadiazine on tear production and the fluctuations of Schirmer tear test values in horses.. Vet Ophthalmol 2004 Nov-Dec;7(6):385-90.
- Gelatt KN, Gum GG, Mackay E. Evaluation of mydriatics in horses. Vet Comp Ophthalmol 1995;5:104–107.
- Beech J, Zappala RA, Smith G, Lindborg S. Schirmer tear test results in normal horses and ponies: effect of age, season, environment, sex, time of day and placement of strips.. Vet Ophthalmol 2003 Sep;6(3):251-4.
- Williams RD, Manning JP, Peiffer RL. The Schirmer tear test in equine: normal values and the contribution of the gland of nictitating membrane. J Equine Med Surg 1979;3:117–119.
- Serruya LG, Nogueira DC, Hida RY. Schirmer test performed with open and closed eyes: variations in normal individuals.. Arq Bras Oftalmol 2009 Jan-Feb;72(1):65-7.
- Serin D, Karsloğlu S, Kyan A, Alagöz G. A simple approach to the repeatability of the Schirmer test without anesthesia: eyes open or closed?. Cornea 2007 Sep;26(8):903-6.
- Kashkouli MB, Pakdel F, Amani A, Asefi M, Aghai GH, Falavarjani KG. A modified Schirmer test in dry eye and normal subjects: open versus closed eye and 1-minute versus 5-minute tests.. Cornea 2010 Apr;29(4):384-7.
- Golebiowski B, Papas E, Stapleton F. Assessing the sensory function of the ocular surface: implications of use of a non-contact air jet aesthesiometer versus the Cochet-Bonnet aesthesiometer.. Exp Eye Res 2011 May;92(5):408-13.
- Kalf KL, Utter ME, Wotman KL. Evaluation of duration of corneal anesthesia induced with ophthalmic 0.5% proparacaine hydrochloride by use of a Cochet-Bonnet aesthesiometer in clinically normal horses.. Am J Vet Res 2008 Dec;69(12):1655-8.
- Crispin SM. Tear-deficient and evaporative dry eye syndromes of the horse.. Vet Ophthalmol 2000;3(2-3):87-92.
- Maggs DJ, Miller PE, Ofri R. Slatter’s fundamentals of veterinary ophthalmology. 5. Missouri: Elsevier; 2013. pp. 95–96.
- Gilger BC. Equine ocular examination route and advanced diagnostic techniques: equine ophthalmology. 2. Amsterdam: Elsevier Saunders; 2011.
- Hartley C, Williams DL, Adams VJ. Effect of age, gender, weight, and time of day on tear production in normal dogs.. Vet Ophthalmol 2006 Jan-Feb;9(1):53-7.
- Piccione G, Giannetto C, Fazio F, Giudice E. Daily rhythm of tear production in normal horse.. Vet Ophthalmol 2008 Sep;11 Suppl 1:57-60.
- Sindak N, Kandemir L, Yertürk M, Biricik HS. Measurement of phenol red thread tear test in Arabian and throughbred horses.. Vet Ophthalmol 2010 Jul;13(4):219-21.
- Spiess BM, Wilcock BP, Physick-Sheard PW. Eosinophilic granulomatous dacryoadenitis causing bilateral keratoconjunctivitis sicca in a horse.. Equine Vet J 1989 May;21(3):226-8.
- Schwarz BC, Sallmutter T, Nell B. Keratoconjunctivitis sicca attributable to parasympathetic facial nerve dysfunction associated with hypothyroidism in a horse.. J Am Vet Med Assoc 2008 Dec 1;233(11):1761-6.
Citations
This article has been cited 3 times.- Kovaļčuka L, Mūrniece G. Normal reference ranges of ocular physiology and sonographic biometry of Latvian Hunting dogs. Vet World 2019 Apr;13(4):807-811.
- Pe'er O, Ofri R, Sebbag L. Schirmer tear test-1 with open or closed eyelids: An evaluation in brachycephalic and nonbrachycephalic dogs. Vet Ophthalmol 2025 Jan;28(1):21-27.
- Cinar H, Yanmaz LE, Buyukkaraca N, Kaya Z, Kosuncu M. Comparing the effects of intraocular pressure and tear production measurements in horses in two different environments: Horse stable and medical barn. Equine Vet J 2025 Jan;57(1):271-276.
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