Rhodococcus equi pleuropneumonia in an adult horse.
Abstract: A 10-year-old warmblood gelding was evaluated for intermittent pyrexia, dullness, weight loss, and progressive respiratory disease. Multifocal necrotic pneumonia and pleuritis due to Rhodococcus equi infection was diagnosed. Case management is discussed, as well as factors that may have led to this rare cause of pleuropneumonia in an adult horse.
Publication Date: 2002-09-21 PubMed ID: 12240529PubMed Central: PMC339555
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Summary
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The paper discusses a rare case of Rhodococcus equi pleuropneumonia, a serious lung infection, in a 10-year-old warmblood gelding horse, detailing the symptoms, diagnosis, and factors contributing to the disease.
Case Presentation
- The research paper begins with the case presentation of a 10-year-old warmblood gelding horse that was exhibiting unusual symptoms. These symptoms included intermittent pyrexia (fever), dullness (a lack of energy, or lethargy), weight loss, and progressive respiratory disease.
Diagnosis
- The clinicians in this study performed various tests and examinations to determine the cause of the horse’s illness. Multifocal necrotic pneumonia and pleuritis – inflammation of the tissues that line the lungs and chest cavity – were identified. This was an unusual finding, considering the horse’s age, breed, and overall health condition prior to the infectious disease.
- A further microbiological examination revealed that the infection was caused by Rhodococcus equi, a bacterium usually affecting young foals (horses less than one year old), making it a rare cause of pleuropneumonia in an adult horse.
Case Management
- The paper then discusses the management and treatment of this case. Given the uncommon nature of this infection in an adult horse, there is no established protocol for treatment, so strategies must be tailored for each individual case.
Discussion of Contributing Factors
- The research paper also delves into a discussion of the potential factors that could have led to such an unusual infection in an adult horse. These factors might include environmental conditions, the health status of the horse prior to infection, and whether these might have compromised the horse’s immune response, making it susceptible to Rhodococcus equi infection.
Conclusion
- As an exploratory investigation into a rare occurrence, this paper seeks not only to provide insights for similar future cases, but also to encourage continued research into the conditions and factors that can lead to an adult horse contracting Rhodococcus equi pleuropneumonia.
Cite This Article
APA
Vengust M, Staempfli H, Prescott JF.
(2002).
Rhodococcus equi pleuropneumonia in an adult horse.
Can Vet J, 43(9), 706-708.
Publication
Researcher Affiliations
- Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.
MeSH Terms
- Actinomycetales Infections / microbiology
- Actinomycetales Infections / veterinary
- Age Factors
- Animals
- Fatal Outcome
- Horse Diseases / microbiology
- Horses
- Male
- Pleuropneumonia / microbiology
- Pleuropneumonia / veterinary
- Rhodococcus equi / isolation & purification
- Rhodococcus equi / pathogenicity
References
This article includes 15 references
- Giguère S, Prescott JF. Clinical manifestations, diagnosis, treatment, and prevention of Rhodococcus equi infections in foals.. Vet Microbiol 1997 Jun 16;56(3-4):313-34.
- Prescott JF. Rhodococcus equi: an animal and human pathogen.. Clin Microbiol Rev 1991 Jan;4(1):20-34.
- Hondalus MK. Pathogenesis and virulence of Rhodococcus equi.. Vet Microbiol 1997 Jun 16;56(3-4):257-68.
- Scott MA, Graham BS, Verrall R, Dixon R, Schaffner W, Tham KT. Rhodococcus equi--an increasingly recognized opportunistic pathogen. Report of 12 cases and review of 65 cases in the literature.. Am J Clin Pathol 1995 May;103(5):649-55.
- Freestone JF, Hietala S, Moulton J, Vivrette S. Acquired immunodeficiency in a seven-year-old horse.. J Am Vet Med Assoc 1987 Mar 15;190(6):689-91.
- Genetzky RM, Bettcher MP, Arp LH, White PL. Corynebacterium equi infection in a mare. Mod Vet Pract 1982;63:876–879.
- Roberts MC, Hodgson DR, Kelly WR. Corynebacterium equi infection in an adult horse.. Aust Vet J 1980 Feb;56(2):96-7.
- Zink MC, Yager JA, Smart NL. Corynebacterium equi Infections in Horses, 1958-1984: A Review of 131 Cases.. Can Vet J 1986 May;27(5):213-7.
- Nicholson VM, Prescott JF. Restriction enzyme analysis of the virulence plasmids of VapA-positive Rhodococcus equi strains isolated from humans and horses.. J Clin Microbiol 1997 Mar;35(3):738-40.
- Sweeney CR, Holcombe SJ, Barningham SC, Beech J. Aerobic and anaerobic bacterial isolates from horses with pneumonia or pleuropneumonia and antimicrobial susceptibility patterns of the aerobes.. J Am Vet Med Assoc 1991 Mar 1;198(5):839-42.
- Ellenberger MA, Genetzky RM. Rhodococcus equi infections: literature review. Compend Contin Educ Pract Vet 1986;8: S414–S424.
- Hines MT, Paasch KM, Alperin DC, Palmer GH, Westhoff NC, Hines SA. Immunity to Rhodococcus equi: antigen-specific recall responses in the lungs of adult horses.. Vet Immunol Immunopathol 2001 May 10;79(1-2):101-14.
- Linares MJ, López-Encuentra A, Perea S. Chronic pneumonia caused by Rhodococcus equi in a patient without impaired immunity.. Eur Respir J 1997 Jan;10(1):248-50.
- Sweeney CR, Sweeney RW, Divers TJ. Rhodococcus equi pneumonia in 48 foals: response to antimicrobial therapy.. Vet Microbiol 1987 Aug;14(3):329-36.
- Prescott JF, Nicholson VM. The effects of combinations of selected antibiotics on the growth of Corynebacterium equi.. J Vet Pharmacol Ther 1984 Mar;7(1):61-4.
Citations
This article has been cited 4 times.- Sting R, Schwabe I, Kieferle M, Münch M, Rau J. Fatal Infection in an Alpaca (Vicugna pacos) Caused by Pathogenic Rhodococcus equi.. Animals (Basel) 2022 May 19;12(10).
- Aslam MW, Lau SF, Chin CSL, Ahmad NI, Rahman NA, Kuppusamy K, Omar S, Radzi R. Clinicopathological and radiographic features in 40 cats diagnosed with pulmonary and cutaneous Rhodococcus equi infection (2012-2018).. J Feline Med Surg 2020 Aug;22(8):774-790.
- Majidzadeh M, Fatahi-Bafghi M. Current taxonomy of Rhodococcus species and their role in infections.. Eur J Clin Microbiol Infect Dis 2018 Nov;37(11):2045-2062.
- Gudeta DD, Moodley A, Bortolaia V, Guardabassi L. vanO, a new glycopeptide resistance operon in environmental Rhodococcus equi isolates.. Antimicrob Agents Chemother 2014;58(3):1768-70.
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