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Home / Equine Research Bank / J Parasitol / Sarcocystis neurona n. sp. (Protozoa: Apicomplexa), the etio...
The Journal of parasitology1991; 77(2); 212-218;

Sarcocystis neurona n. sp. (Protozoa: Apicomplexa), the etiologic agent of equine protozoal myeloencephalitis.

Abstract: Sarcocystis neuronan n. sp. is proposed for the apicomplexan taxon associated with myeloencephalitis in horses. Only asexual stages of this parasite presently are known, and they are found within neuronal cells and leukocytes of the brain and spinal cord. The parasite is located in the host cell cytoplasm, does not have a parasitophorous vacuole, and divides by endopolygeny. Schizonts are 5-35 microns x 5-20 microns and contain 4-40 merozoites arranged in a rosette around a prominent residual body. Merozoites are approximately 4 x 1 micron, have a central nucleus, and lack rhoptries. Schizonts and merozoites react with Sarcocystis cruzi antiserum but not with Caryospora bigenetica. Toxoplasma gondii, Hammondia hammondi, or Neospora caninum antisera in an immunohistochemical test.
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Publication Date: 1991-04-01 PubMed ID: 1901359
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  • Comparative Study
  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article is about a new species of parasite named Sarcocystis neurona that causes myeloencephalitis, a brain and spinal cord disease, in horses. The study also describes the characteristics of this parasite and its asexual reproduction stages.

About Sarcocystis neurona

The research paper introduces a new species of Apicomplexa taxon, named Sarcocystis neurona. This parasite is associated with a disease called myeloencephalitis, which affects the brain and spinal cord in horses. At present, only the asexual stages of this parasite are known.

  • The parasite resides within the neurons and leukocytes of the brain and spinal cord of the horse.
  • The location of the parasite is within the host cell cytoplasm; it does not possess a parasitophorous vacuole and reproduces by endopolygeny, a form of asexual reproduction.

The Features of Sarcocystis neurona

The paper then delves into the physical attributes of the parasite:

  • Schizonts, the asexual reproduction stage of the parasite, measured in this study are found to be between 5-35 microns x 5-20 microns in size and contain 4-40 merozoites, which are arranged in a rosette around a prominent residual body.
  • Merozoites, the proliferating form of the parasite, are seen to be approximately 4 x 1 micron in size, possess a central nucleus, and lack rhoptries, specialized secretory organelles found in apicomplexan parasites.

Inbuilt Defense Mechanism

The paper also found that these schizonts and merozoites react, or bind, to antibodies derived from another species known as Sarcocystis cruzi:

  • This suggests that the Sarcocystis neurona parasites carry antigens (proteins that can elicit an immune response) that can bind to Sarcocystis cruzi antibodies, hence potentially indicating a mechanism of immune evasion or defense.
  • In contrast, the parasites do not react to antibodies from Caryospora bigenetica, Toxoplasma gondii, Hammondia hammondi, or Neospora caninum, indicating potential differences in their antigenic profiles.

Cite This Article

APA
Dubey JP, Davis SW, Speer CA, Bowman DD, de Lahunta A, Granstrom DE, Topper MJ, Hamir AN, Cummings JF, Suter MM. (1991). Sarcocystis neurona n. sp. (Protozoa: Apicomplexa), the etiologic agent of equine protozoal myeloencephalitis. J Parasitol, 77(2), 212-218.

Publication

The Journal of parasitology
ISSN: 0022-3395
NlmUniqueID: 7803124
Country: United States
Language: English
Volume: 77
Issue: 2
Pages: 212-218

Researcher Affiliations

Dubey, J P
  • Livestock and Poultry Sciences Institute, U.S. Department of Agriculture, Beltsville, Maryland 20705.
Davis, S W
    Speer, C A
      Bowman, D D
        de Lahunta, A
          Granstrom, D E
            Topper, M J
              Hamir, A N
                Cummings, J F
                  Suter, M M

                    MeSH Terms

                    • Animals
                    • Encephalomyelitis / parasitology
                    • Encephalomyelitis / veterinary
                    • Horse Diseases / parasitology
                    • Horses
                    • Microscopy, Electron
                    • Sarcocystis / anatomy & histology
                    • Sarcocystis / classification
                    • Sarcocystis / ultrastructure
                    • Sarcocystosis / parasitology
                    • Sarcocystosis / veterinary

                    Citations

                    This article has been cited 21 times.
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