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Veterinary pathology2001; 38(2); 230-232; doi: 10.1354/vp.38-2-230

Septicemia and peritonitis due to Actinobacillus equuli infection in an adult horse.

Abstract: Actinobacillus equuli is a rare cause of peritonitis in adult horses. Septicemia and peritonitis due to A. equuli were diagnosed at necropsy in an 8-year-old Saddlebred mare. The origin of the infection was not known; however, small necrotic colonic mucosal lesions presumed to have been caused by phenylbutazone treatment may have allowed bacterial invasion. A good response to antimicrobial treatment has been documented in the small numbers of previously reported acute cases of peritonitis. Because it is potentially treatable, it is important for pathologists and clinicians to identify horses with A. equuli peritonitis.
Publication Date: 2001-03-31 PubMed ID: 11280382DOI: 10.1354/vp.38-2-230Google Scholar: Lookup
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Summary

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This study discusses a case of a rare Actinobacillus equuli infection in an adult horse which led to septicemia and peritonitis, noting that the origin of the infection is unknown, but potential links to treatment related injuries have been suggested.

Introduction to the Study

  • The study presents a case of a rare type of infection, Actinobacillus equuli, in an adult horse. This infection lead to septicemia, a severe bloodstream infection, and peritonitis, an inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs.

Main Findings of the Study

  • The infection was discovered at necropsy in an 8-year-old Saddlebred mare. The Saddlebred is a breed of horse known for its easy style of riding and versatility.
  • The researchers were not able to establish the source of the infection. However, they hypothesize that small necrotic colonic mucosal lesions could be the possible source. These lesions were presumed to have been a result of a phenylbutazone treatment, a nonsteroidal anti-inflammatory drug commonly used in treating pain and fever in animals.

Treatment and Importance of Detection

  • The researchers mention that in the few acute cases of A. equuli peritonitis previously reported, the response to antimicrobial treatment has been good. This suggests that if caught early, the infection can potentially be treated effectively with antimicrobials.
  • The paper concludes by highlighting the importance of properly identifying horses suffering from A. equuli peritonitis. Recognition of such infections is crucial for successful treatment and can potentially prevent further deterioration of the horse’s health condition.

Cite This Article

APA
Patterson-Kane JC, Donahue JM, Harrison LR. (2001). Septicemia and peritonitis due to Actinobacillus equuli infection in an adult horse. Vet Pathol, 38(2), 230-232. https://doi.org/10.1354/vp.38-2-230

Publication

ISSN: 0300-9858
NlmUniqueID: 0312020
Country: United States
Language: English
Volume: 38
Issue: 2
Pages: 230-232

Researcher Affiliations

Patterson-Kane, J C
  • Department of Pathology and Infectious Diseases, Royal Veterinary College, Hatfield, Hertfordshire, UK.
Donahue, J M
    Harrison, L R

      MeSH Terms

      • Actinobacillus / isolation & purification
      • Actinobacillus Infections / pathology
      • Actinobacillus Infections / veterinary
      • Animals
      • Bacteremia / microbiology
      • Bacteremia / pathology
      • Bacteremia / veterinary
      • Fatal Outcome
      • Female
      • Histocytochemistry / veterinary
      • Horse Diseases / microbiology
      • Horse Diseases / pathology
      • Horses
      • Intestines / pathology
      • Lung / pathology
      • Lymph Nodes / pathology
      • Peritonitis / microbiology
      • Peritonitis / pathology
      • Peritonitis / veterinary

      Citations

      This article has been cited 3 times.
      1. Uchida-Fujii E, Niwa H, Kinoshita Y, Nukada T. Actinobacillus species isolated from Japanese Thoroughbred racehorses in the last two decades. J Vet Med Sci 2019 Sep 3;81(9):1234-1237.
        doi: 10.1292/jvms.19-0192pubmed: 31292334google scholar: lookup
      2. Odelros E, Kendall A, Hedberg-Alm Y, Pringle J. Idiopathic peritonitis in horses: a retrospective study of 130 cases in Sweden (2002-2017). Acta Vet Scand 2019 Apr 25;61(1):18.
        doi: 10.1186/s13028-019-0456-2pubmed: 31023351google scholar: lookup
      3. Huang BF, Kropinski AM, Bujold AR, MacInnes JI. Complete genome sequence of Actinobacillus equuli subspecies equuli ATCC 19392(T). Stand Genomic Sci 2015;10:32.
        doi: 10.1186/s40793-015-0009-xpubmed: 26203343google scholar: lookup