Serratia marcescens endocarditis in a horse.
Abstract: Serratia marcescens was the causative agent of bacterial endocarditis in a 2-year-old Arabian stallion. The horse was treated with broad-spectrum antibiotics for 1 month. The horse died several months after treatment was discontinued. To our knowledge, Serratia marcescens has not been reported as the cause of bacterial endocarditis in horses; however, multiple cases of bacterial endocarditis attributable to Serratia marcescens have been documented in human beings. The bacteria is most commonly isolated in immune-compromised patients.
Publication Date: 1992-04-01 PubMed ID: 1577651 The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Case Reports
- Journal Article
Summary
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The research article reports a case of bacterial endocarditis caused by Serratia marcescens in a 2-year-old Arabian stallion, which eventually resulted in its death. This claimed to be the first reported case of such infection in horses, although multiple occurrences in humans have been well-documented.
Case Introduction
- The research discusses a rare case of endocarditis, an inflammation of the inner layer of the heart, caused by the bacterium Serratia marcescens in a 2-year-old Arabian stallion.
- This bacterial strain is commonly found in immune-compromised human patients but has not been reported before in horses, making it a unique case in veterinary medicine.
Treatment and Outcome
- The horse was subjected to a month-long treatment using broad-spectrum antibiotics to combat the infection.
- Despite the treatment, the horse’s condition worsened and it died several months after the discontinuation of treatment.
Implication of the Study
- The case study challenges the belief that Serratia marcescens only infects immunocompromised human patients, revealing its potential threat to animals as well.
- Further research is encouraged in order to better understand the behavioral pattern of this bacterium in different hosts and seek more effective treatment options for animals.
- The inability to treat the horse effectively, despite using broad-spectrum antibiotics, indicates potential antibiotic resistance by Serratia marcescens and calls for a better approach to manage such infections in animals.
Cite This Article
APA
Ewart S, Brown C, Derksen F, Kufuor-Mensa E.
(1992).
Serratia marcescens endocarditis in a horse.
J Am Vet Med Assoc, 200(7), 961-963.
Publication
Researcher Affiliations
- Department of Large Animal Clinical Sciences, Michigan State University, East Lansing 48824.
MeSH Terms
- Animals
- Echocardiography / veterinary
- Endocarditis, Bacterial / diagnostic imaging
- Endocarditis, Bacterial / microbiology
- Endocarditis, Bacterial / veterinary
- Horse Diseases / diagnostic imaging
- Horse Diseases / microbiology
- Horses
- Male
- Mitral Valve / pathology
- Serratia Infections / diagnostic imaging
- Serratia Infections / microbiology
- Serratia Infections / veterinary
- Serratia marcescens / isolation & purification
Citations
This article has been cited 1 times.- Hardefeldt L, Thomas K, Page S, Norris J, Browning G, El Hage C, Stewart A, Gilkerson J, Muscatello G, Verwilghen D, van Galen G, Bauquier J, Cuming R, Reynolds B, Whittaker C, Wilkes E, Clulow J, Burden C, Begg L. Antimicrobial prescribing guidelines for horses in Australia. Aust Vet J 2025 Dec;103(12):781-889.
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