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Veterinary clinical pathology1980; 9(1); 27-30; doi: 10.1111/j.1939-165x.1980.tb00890.x

Serum alkaline phosphatase in pregnant mares.

Abstract: Serum alkaline phosphatase was measured in ten mares during various stages of gestation. No significant change in serum alkaline phosphatase activity was detected during pregnancy. These data suggest that interpretation of serum alkaline phosphatase in horses can be made independently of their pregnancy status.
Publication Date: 1980-01-01 PubMed ID: 15314775DOI: 10.1111/j.1939-165x.1980.tb00890.xGoogle Scholar: Lookup
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  • Journal Article

Summary

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The research article focuses on assessing the levels of serum alkaline phosphatase in pregnant mares, concluding that their pregnancy status does not significantly impact these levels.

Methodology

  • The study was conducted on ten mares during different stages of their pregnancy. The number of subjects provides a limited but focused sample for the study.
  • During these various stages of gestation, the researchers measured the levels of serum alkaline phosphatase. This enzyme is found in all bodily tissues and is particularly concentrated in the liver, bile ducts, and bone.

Findings

  • Based upon the measurements taken, the researchers established that there was no significant change in serum alkaline phosphatase activity during pregnancy. This means that the enzyme’s activity remained relatively constant regardless of the mares’ pregnancy stages.
  • The constant level of serum alkaline phosphatase in the pregnant mares suggests that this enzyme’s activity in horses does not vary with the horse’s pregnancy status.

Implications

  • The results of this study could be important for equine health diagnostics and treatments. Serum alkaline phosphatase is often measured in clinical biochemistry to help diagnose liver and bone diseases.
  • If the enzyme levels do not change significantly during pregnancy, then any detected changes in a pregnant mare may be a stronger indicator of the potential for a health issue unrelated to pregnancy.
  • Further, veterinarians can interpret serum alkaline phosphatase levels in horses without having to take into account whether the horse is pregnant or not. This could simplify and streamline the diagnostic process.

Cite This Article

APA
Meuten DJ, Kociba G, Threlfall WR, Nogode LA. (1980). Serum alkaline phosphatase in pregnant mares. Vet Clin Pathol, 9(1), 27-30. https://doi.org/10.1111/j.1939-165x.1980.tb00890.x

Publication

ISSN: 1939-165X
NlmUniqueID: 9880575
Country: United States
Language: English
Volume: 9
Issue: 1
Pages: 27-30

Researcher Affiliations

Meuten, D J
  • Department of Veterinary Pathobiology, Department of Veterinary Clinical Science, The Ohio State University, Columbus, Ohio 43210.
Kociba, G
    Threlfall, W R
      Nogode, L A

        Citations

        This article has been cited 1 times.
        1. Ellison RS, Jacobs RM. An attempt to determine the tissue origin of equine serum alkaline phosphatase by isoelectric focusing.. Can J Vet Res 1990 Jan;54(1):119-25.
          pubmed: 2306660