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Serum fructosamine concentrations in relation to metabolic changes during late pregnancy and early lactation in mares.

Abstract: The changes in blood serum fructosamine concentrations as indicators of glycaemia during a longer period of time were investigated in mares during late pregnancy and early lactation, as well as their relationship to the changes in the concentration of biochemical indicators of energetic status. The samples were taken from eleven mares on 60 +/- 10 and 20 +/- 10 days before foaling, and 20 +/- 10 and 60 +/- 10 days after foaling. Concentrations of serum fructosamine, non-esterified fatty acids and triglycerides were higher during late pregnancy (from P < 0.05 to P < 0.0005), while the concentrations of beta- hydroxybutyrate increased significantly (P < 0.00001) during early lactation. A significant correlation between the concentrations of fructosamine and metabolic parameters was observed. The results indicate a relationship between energetic status and serum fructosamine in mares. Higher concentrations of fructosamine are related to the adaptation to late pregnancy. Therefore, the measurement of the serum fructosamine concentrations could serve as an indicator of energetic status of mares during pregnancy and lactation.
Publication Date: 2010-03-25 PubMed ID: 20329650
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

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The research examines changes in the blood serum fructosamine (an indicator of long-term blood sugar levels) in pregnant and lactating mares. The findings suggest that higher fructosamine concentrations during late pregnancy are linked to the mare’s adaptation and that they could serve as an indicator of the animal’s energy status during pregnancy and lactation.

Study Overview

  • The main objective of the research was to investigate fluctuations in blood serum fructosamine in mares during the late stages of pregnancy and the early stages of lactation. The study also observed these changes in relation to varying concentrations of indicators of their energy status.
  • Fructosamine is used as an indicator of blood sugar levels over an extended period; thus, the researchers used this to understand the mares’ glycaemic condition over a longer duration.

Methodology

  • The study was conducted on a sample size of eleven mares.
  • Blood samples were taken from these mares approximately 60 and 20 days prior to delivering their foals, and 20 and 60 days after they had given birth.
  • Concentrations of fructosamine, non-esterified fatty acids, and triglycerides were primarily analyzed, as well as beta-hydroxybutyrate levels.

Findings

  • The results showed higher concentrations of fructosamine, non-esterified fatty acids, and triglycerides during the late pregnancy period (less than 60 days before foaling).
  • There was also a significant increase in beta-hydroxybutyrate levels during early lactation (just after the mares had given birth).
  • A noteworthy correlation was found between these fluctuating concentrations of fructosamine and the metabolic parameters related to the mares’ energy status.

Conclusion

  • Overall, the increased fructosamine concentrations during late pregnancy indicate an adaptation process detactable through testing the mares’ blood serum.
  • These changes, as observed by the researchers, suggest that the measurement of serum fructosamine could be used as a reliable indicator of a mare’s energy status during late pregnancy and lactation stages.

Cite This Article

APA
Filipović N, Stojević Z, Prvanović N. (2010). Serum fructosamine concentrations in relation to metabolic changes during late pregnancy and early lactation in mares. Berl Munch Tierarztl Wochenschr, 123(3-4), 169-173.

Publication

ISSN: 0005-9366
NlmUniqueID: 0003163
Country: Germany
Language: English
Volume: 123
Issue: 3-4
Pages: 169-173

Researcher Affiliations

Filipović, Natalija
  • Department of Physiology and Radiobiology, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia. nfilipovic@vef.hr
Stojević, Zvonko
    Prvanović, Nikica

      MeSH Terms

      • Animals
      • Biomarkers / blood
      • Female
      • Fructosamine / blood
      • Horses
      • Lactation / physiology
      • Pregnancy
      • Pregnancy, Animal / blood

      Citations

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