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Sperm trajectories form chiral ribbons.
Abstract: We report the discovery of an entirely new three-dimensional (3D) swimming pattern observed in human and horse sperms. This motion is in the form of 'chiral ribbons', where the planar swing of the sperm head occurs on an osculating plane creating in some cases a helical ribbon and in some others a twisted ribbon. The latter, i.e., the twisted ribbon trajectory, also defines a minimal surface, exhibiting zero mean curvature for all the points on its surface. These chiral ribbon swimming patterns cannot be represented or understood by already known patterns of sperms or other micro-swimmers. The discovery of these unique patterns is enabled by holographic on-chip imaging of >33,700 sperm trajectories at >90-140 frames/sec, which revealed that only ~1.7% of human sperms exhibit chiral ribbons, whereas it increases to ~27.3% for horse sperms. These results might shed more light onto the statistics and biophysics of various micro-swimmers' 3D motion.
Publication Date: 2013-04-17 PubMed ID: 23588811PubMed Central: PMC3630328DOI: 10.1038/srep01664Google Scholar: Lookup The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
- Research Support
- N.I.H.
- Extramural
- Research Support
- U.S. Gov't
- Non-P.H.S.
Summary
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The research investigates a newly discovered three-dimensional swimming pattern found in human and horse sperm cells, which they describe as ‘chiral ribbons’. Through the utilization of advanced imaging techniques, the researchers provide insights into the rare and unique swimming patterns exhibited by these sperm cells.
The Discovery of a New 3D Swimming Pattern
- The researchers revealed a never-before-seen three-dimensional swimming pattern in human and horse sperm.
- This unique motion is described as ‘chiral ribbons,’ characterized by a planar swing of the sperm cell’s head that happens on an osculating plane. This movement often creates a helical or twisted ribbon shape.
- Notably, the twisted ribbon trajectory constitutes a minimal surface with zero mean curvature for all points on its surface.
- This new discovery cannot be depicted or understood using known patterns of sperm or other micro-swimmers, making it a breakthrough in the understanding of sperm cell motility.
Holographic On-chip Imaging and Findings
- The research team uncovered these unique patterns through holographic on-chip imaging of over 33,700 sperm trajectories, captured at a speed of 90-140 frames per second.
- The analysis of these images showed that only about 1.7% of human sperm cells displayed these chiral ribbon patterns. The occurrence was markedly higher in horse sperm, where approximately 27.3% showed these patterns.
Implications of the Discovery
- This study provides further insight into the statistics and biophysics of various micro-swimmers’ 3D movements.
- The findings could have significant implications for understanding reproductive biology and may potentially influence future studies in fertility and reproduction.
- The new sperm movement pattern underlines the complexity of micro-swimmer locomotion, emphasizing the need for advanced imaging techniques in uncovering unobserved phenomena.
Cite This Article
APA
Su TW, Choi I, Feng J, Huang K, McLeod E, Ozcan A.
(2013).
Sperm trajectories form chiral ribbons.
Sci Rep, 3, 1664.
https://doi.org/10.1038/srep01664 Publication
Researcher Affiliations
- Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA.
MeSH Terms
- Animals
- Cells, Cultured
- Horses
- Humans
- Male
- Models, Biological
- Species Specificity
- Sperm Motility / physiology
- Spermatozoa / cytology
- Spermatozoa / physiology
Grant Funding
- DP2 OD006427 / NIH HHS
- DP2OD006427 / NIH HHS
Conflict of Interest Statement
A.O. is the co-founder of a start-up company that aims to commercialize lensfree microscopy tools.
References
This article includes 49 references
Citations
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