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Veterinary dermatology2009; 20(4); 249-259; doi: 10.1111/j.1365-3164.2009.00763.x

Sporotrichosis: a retrospective evaluation of 23 cases seen in northern California (1987-2007).

Abstract: Sporotrichosis is an uncommon to rare cutaneous and subcutaneous mycosis of animals and humans caused by the dimorphic fungus Sporothrix schenckii. Twenty-three mammalian cases of sporotrichosis examined between 1987 and 2007 at the University of California, Davis - Veterinary Medical Teaching Hospital, were retrospectively evaluated with regard to the historical, clinical, diagnostic and treatment findings. Cats were the most common species affected (n = 14). In addition, sporotrichosis was diagnosed in four dogs, four horses and a donkey. Six of 23 cases were diagnosed with the localized cutaneous form of sporotrichosis (four cats, one dog, one horse), 10 with the cutaneous-lymphatic form (four cats, two dogs, three horses and a donkey), and seven with the disseminated form (six cats, one dog). Two of 23 cases did not have skin lesions at the time of diagnosis (one cat, one dog). The most common mode of diagnosis was demonstration of S. schenckii on histopathological evaluation of tissue. In contrast with most previously described sporotrichosis infections in cats, few to no fungal organisms were seen in histopathological samples (haematoxylin and eosin and special stains) in five of the 14 cats. Treatments received included itraconazole (12 cats, one dog), ketoconazole (three dogs), fluconazole (one cat, one donkey), sodium iodide (four horses, one cat) and potassium iodide (one cat, one horse, one donkey). The prognosis for successful treatment was good in all species. Fluconazole was successful in inducing resolution of the cutaneous lesions and controlling the infection in one cat with disseminated sporotrichosis.
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Publication Date: 2009-08-08 PubMed ID: 19659536DOI: 10.1111/j.1365-3164.2009.00763.xGoogle Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research looked into 23 cases of sporotrichosis, a rare skin infection in animals and humans caused by a fungus, that occurred between 1987 and 2007 in Northern California. The study aimed to understand the history, symptoms, diagnosis, and treatment.

Study Overview

The research focused on sporotrichosis, an infection caused by the Sporothrix schenckii fungus. This study analyzed:

  • 23 instances of the infection that occurred between 1987 and 2007
  • The different species involved, which included cats, dogs, horses, and a donkey

Research Findings

The findings were multifaceted and included the following elements:

  • Cats were the most affected species, followed by dogs, horses, and a donkey.
  • Different forms of sporotrichosis were found – localized cutaneous, cutaneous-lymphatic, and disseminated.
  • Diagnosis most commonly occurred through histopathological evaluation of tissue.
  • In some cat cases, few to no fungal organisms were visible in the samples examined.

Treatment and Prognosis

The study also looked into the treatment measures employed and their effectiveness.

  • Treatments included itraconazole, ketoconazole, fluconazole, sodium iodide, and potassium iodide.
  • The prognosis was generally good across all species upon treatment.
  • Fluconazole was particularly successful in resolving cutaneous lesions and controlling infection in one cat with disseminated sporotrichosis.

This research contributes significant insights into sporotrichosis cases and provides clues regarding potential treatments, promising a good prognosis.

Cite This Article

APA
Crothers SL, White SD, Ihrke PJ, Affolter VK. (2009). Sporotrichosis: a retrospective evaluation of 23 cases seen in northern California (1987-2007). Vet Dermatol, 20(4), 249-259. https://doi.org/10.1111/j.1365-3164.2009.00763.x

Publication

Veterinary dermatology
ISSN: 1365-3164
NlmUniqueID: 9426187
Country: England
Language: English
Volume: 20
Issue: 4
Pages: 249-259

Researcher Affiliations

Crothers, Samantha L
  • Department of Medicine and Epidemiology, Veterinary Medical Teaching Hospital, University of California, Davis, California 95616, USA. scrothers@vmth.ucdavis.edu
White, Stephen D
    Ihrke, Peter J
      Affolter, Verena K

        MeSH Terms

        • Animals
        • Antifungal Agents / therapeutic use
        • California / epidemiology
        • Cat Diseases / drug therapy
        • Cat Diseases / epidemiology
        • Cat Diseases / microbiology
        • Cat Diseases / pathology
        • Cats
        • Dog Diseases / drug therapy
        • Dog Diseases / epidemiology
        • Dog Diseases / microbiology
        • Dog Diseases / pathology
        • Dogs
        • Equidae
        • Female
        • Male
        • Retrospective Studies
        • Sporotrichosis / drug therapy
        • Sporotrichosis / epidemiology
        • Sporotrichosis / pathology
        • Sporotrichosis / veterinary

        Citations

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