Sporotrichosis: a retrospective evaluation of 23 cases seen in northern California (1987-2007).
Abstract: Sporotrichosis is an uncommon to rare cutaneous and subcutaneous mycosis of animals and humans caused by the dimorphic fungus Sporothrix schenckii. Twenty-three mammalian cases of sporotrichosis examined between 1987 and 2007 at the University of California, Davis - Veterinary Medical Teaching Hospital, were retrospectively evaluated with regard to the historical, clinical, diagnostic and treatment findings. Cats were the most common species affected (n = 14). In addition, sporotrichosis was diagnosed in four dogs, four horses and a donkey. Six of 23 cases were diagnosed with the localized cutaneous form of sporotrichosis (four cats, one dog, one horse), 10 with the cutaneous-lymphatic form (four cats, two dogs, three horses and a donkey), and seven with the disseminated form (six cats, one dog). Two of 23 cases did not have skin lesions at the time of diagnosis (one cat, one dog). The most common mode of diagnosis was demonstration of S. schenckii on histopathological evaluation of tissue. In contrast with most previously described sporotrichosis infections in cats, few to no fungal organisms were seen in histopathological samples (haematoxylin and eosin and special stains) in five of the 14 cats. Treatments received included itraconazole (12 cats, one dog), ketoconazole (three dogs), fluconazole (one cat, one donkey), sodium iodide (four horses, one cat) and potassium iodide (one cat, one horse, one donkey). The prognosis for successful treatment was good in all species. Fluconazole was successful in inducing resolution of the cutaneous lesions and controlling the infection in one cat with disseminated sporotrichosis.
Publication Date: 2009-08-08 PubMed ID: 19659536DOI: 10.1111/j.1365-3164.2009.00763.xGoogle Scholar: Lookup
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- Journal Article
Summary
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The research looked into 23 cases of sporotrichosis, a rare skin infection in animals and humans caused by a fungus, that occurred between 1987 and 2007 in Northern California. The study aimed to understand the history, symptoms, diagnosis, and treatment.
Study Overview
The research focused on sporotrichosis, an infection caused by the Sporothrix schenckii fungus. This study analyzed:
- 23 instances of the infection that occurred between 1987 and 2007
- The different species involved, which included cats, dogs, horses, and a donkey
Research Findings
The findings were multifaceted and included the following elements:
- Cats were the most affected species, followed by dogs, horses, and a donkey.
- Different forms of sporotrichosis were found – localized cutaneous, cutaneous-lymphatic, and disseminated.
- Diagnosis most commonly occurred through histopathological evaluation of tissue.
- In some cat cases, few to no fungal organisms were visible in the samples examined.
Treatment and Prognosis
The study also looked into the treatment measures employed and their effectiveness.
- Treatments included itraconazole, ketoconazole, fluconazole, sodium iodide, and potassium iodide.
- The prognosis was generally good across all species upon treatment.
- Fluconazole was particularly successful in resolving cutaneous lesions and controlling infection in one cat with disseminated sporotrichosis.
This research contributes significant insights into sporotrichosis cases and provides clues regarding potential treatments, promising a good prognosis.
Cite This Article
APA
Crothers SL, White SD, Ihrke PJ, Affolter VK.
(2009).
Sporotrichosis: a retrospective evaluation of 23 cases seen in northern California (1987-2007).
Vet Dermatol, 20(4), 249-259.
https://doi.org/10.1111/j.1365-3164.2009.00763.x Publication
Researcher Affiliations
- Department of Medicine and Epidemiology, Veterinary Medical Teaching Hospital, University of California, Davis, California 95616, USA. scrothers@vmth.ucdavis.edu
MeSH Terms
- Animals
- Antifungal Agents / therapeutic use
- California / epidemiology
- Cat Diseases / drug therapy
- Cat Diseases / epidemiology
- Cat Diseases / microbiology
- Cat Diseases / pathology
- Cats
- Dog Diseases / drug therapy
- Dog Diseases / epidemiology
- Dog Diseases / microbiology
- Dog Diseases / pathology
- Dogs
- Equidae
- Female
- Male
- Retrospective Studies
- Sporotrichosis / drug therapy
- Sporotrichosis / epidemiology
- Sporotrichosis / pathology
- Sporotrichosis / veterinary
Citations
This article has been cited 18 times.- Figueiredo ABF, Magalhães MAFM, Tassinari WS, Gremião IDF, Miranda LHM, Menezes RC, Pereira SA. Spatial Distribution of Canine Sporotrichosis in Rio de Janeiro, Brazil (1998-2018) and Its Correlation with Socioeconomic Conditions.. J Fungi (Basel) 2022 Nov 15;8(11).
- Alvarez CM, Oliveira MME, Pires RH. Sporotrichosis: A Review of a Neglected Disease in the Last 50 Years in Brazil.. Microorganisms 2022 Oct 30;10(11).
- Morgado DS, Castro R, Ribeiro-Alves M, Corrêa-Moreira D, Castro-Alves J, Pereira SA, Menezes RC, Oliveira MME. Global distribution of animal sporotrichosis: A systematic review of Sporothrix sp. identified using molecular tools.. Curr Res Microb Sci 2022;3:100140.
- Boechat JS, Oliveira MME, Gremião IDF, Almeida-Paes R, Machado ACS, Zancopé-Oliveira RM, Oliveira RVC, Morgado DS, Corrêa ML, Figueiredo ABF, Menezes RC, Pereira SA. Sporothrix brasiliensis and Feline Sporotrichosis in the Metropolitan Region of Rio de Janeiro, Brazil (1998-2018).. J Fungi (Basel) 2022 Jul 20;8(7).
- Rossow JA, Queiroz-Telles F, Caceres DH, Beer KD, Jackson BR, Pereira JG, Ferreira Gremião ID, Pereira SA. A One Health Approach to Combatting Sporothrix brasiliensis: Narrative Review of an Emerging Zoonotic Fungal Pathogen in South America.. J Fungi (Basel) 2020 Oct 26;6(4).
- Gremião IDF, Martins da Silva da Rocha E, Montenegro H, Carneiro AJB, Xavier MO, de Farias MR, Monti F, Mansho W, de Macedo Assunção Pereira RH, Pereira SA, Lopes-Bezerra LM. Guideline for the management of feline sporotrichosis caused by Sporothrix brasiliensis and literature revision.. Braz J Microbiol 2021 Mar;52(1):107-124.
- Boechat JS, Pereira SA, de Sá Machado AC, Viana PG, Almeida-Paes R, Zancopé-Oliveira RM, Gremião IDF, de Oliveira MME. Canine sporotrichosis: polyphasic taxonomy and antifungal susceptibility profiles of Sporothrix species in an endemic area in Brazil.. Braz J Microbiol 2021 Mar;52(1):135-143.
- Nakasu CCT, Waller SB, Ripoll MK, Ferreira MRA, Conceição FR, Gomes ADR, Osório LDG, de Faria RO, Cleff MB. Feline sporotrichosis: a case series of itraconazole-resistant Sporothrix brasiliensis infection.. Braz J Microbiol 2021 Mar;52(1):163-171.
- Han HS, Kano R. Feline sporotrichosis in Asia.. Braz J Microbiol 2021 Mar;52(1):125-134.
- Tovikkai D, Maitrisathit W, Srisuttiyakorn C, Vanichanan J, Thammahong A, Suankratay C. Sporotrichosis: The case series in Thailand and literature review in Southeast Asia.. Med Mycol Case Rep 2020 Mar;27:59-63.
- Duangkaew L, Yurayart C, Limsivilai O, Chen C, Kasorndorkbua C. Cutaneous sporotrichosis in a stray cat from Thailand.. Med Mycol Case Rep 2019 Mar;23:46-49.
- Viana PG, Figueiredo ABF, Gremião IDF, de Miranda LHM, da Silva Antonio IM, Boechat JS, de Sá Machado AC, de Oliveira MME, Pereira SA. Successful Treatment of Canine Sporotrichosis with Terbinafine: Case Reports and Literature Review.. Mycopathologia 2018 Apr;183(2):471-478.
- Zhang Y, Hagen F, Stielow B, Rodrigues AM, Samerpitak K, Zhou X, Feng P, Yang L, Chen M, Deng S, Li S, Liao W, Li R, Li F, Meis JF, Guarro J, Teixeira M, Al-Zahrani HS, Pires de Camargo Z, Zhang L, de Hoog GS. Phylogeography and evolutionary patterns in Sporothrix spanning more than 14 000 human and animal case reports.. Persoonia 2015 Dec;35:1-20.
- Rodrigues AM, de Hoog G, Zhang Y, de Camargo ZP. Emerging sporotrichosis is driven by clonal and recombinant Sporothrix species.. Emerg Microbes Infect 2014 May;3(5):e32.
- Borges TS, Rossi CN, Fedullo JD, Taborda CP, Larsson CE. Isolation of Sporothrix schenckii from the claws of domestic cats (indoor and outdoor) and in captivity in São Paulo (Brazil).. Mycopathologia 2013 Aug;176(1-2):129-37.
- Madrid IM, Mattei AS, Fernandes CG, Nobre Mde O, Meireles MC. Epidemiological findings and laboratory evaluation of sporotrichosis: a description of 103 cases in cats and dogs in southern Brazil.. Mycopathologia 2012 Apr;173(4):265-73.
- Barros MB, de Almeida Paes R, Schubach AO. Sporothrix schenckii and Sporotrichosis.. Clin Microbiol Rev 2011 Oct;24(4):633-54.
- Abrahamian FM, Goldstein EJ. Microbiology of animal bite wound infections.. Clin Microbiol Rev 2011 Apr;24(2):231-46.
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