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The Canadian veterinary journal = La revue veterinaire canadienne2008; 49(5); 494-498;

Suspected transient pseudohypoaldosteronism in a 10-day-old quarter horse foal.

Abstract: A 10-day-old quarter horse colt was presented for signs of disorientation and inability to nurse. Hydronephrosis/hydroureters, with concomitant pyelonephritis and a severe electrolytes disturbance, were diagnosed. The clinical findings closely resembled those described for a syndrome of transient pseudohypoaldosteronism in human neonates. Un poulain Quarter horse âgé de 10 jours a été présenté pour des signes de désorientation et d’incapacité à se nourrir. Une hydronéphrose/hydrouretères avec pyélonéphrite concomitante et débalancement électrolytique sévère ont été diagnostiqués. Les observations cliniques ressemblaient grandement à celles décrites dans le syndrome de pseudohypoaldostéronisme transitoire du nouveauné humain. (Traduit par Docteur André Blouin)
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Publication Date: 2008-06-03 PubMed ID: 18512462PubMed Central: PMC2359497
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study involves a 10-day old Quarter horse foal which had signs of disorientation and inability to nurse, and was diagnosed with severe electrolyte disturbance and hydronephrosis/hydroureters along with pyelonephritis. Its clinical findings were similar to those found in the syndrome of transient pseudohypoaldosteronism in human newborns.

Context of study

  • The research focuses on the case of a 10-day-old Quarter horse colt that exhibited symptoms of disorientation and inability to nurse, which are unusual and cause for concern in young equine offspring.

Clinical findings

  • Upon examination of the foal, it was found to be suffering from a severe electrolyte disturbance. Electrolytes are minerals that are essential for many vital functions in the body. Any disruption in their balance can lead to significant health issues.
  • The foal was also diagnosed with hydronephrosis/hydroureters, a condition characterized by the swelling of one or both of the kidneys due to the buildup of urine, and pyelonephritis, a type of urinary tract infection that generally starts in the urethra or bladder and travels up into the kidneys.

Connections to human conditions

  • The researchers note that these clinical findings resemble the symptoms exhibited in cases of a syndrome known as transient pseudohypoaldosteronism in human infants, a rare disorder characterized by an excess of aldosterone but clinical manifestations of aldosterone deficiency.
  • This connection may open potential avenues for further investigation into cross-species similarity of medical conditions, which could enhance our understanding and treatment of corresponding human illnesses.

Cite This Article

APA
Arroyo LG, Vengust M, Dobson H, Viel L. (2008). Suspected transient pseudohypoaldosteronism in a 10-day-old quarter horse foal. Can Vet J, 49(5), 494-498.

Publication

The Canadian veterinary journal = La revue veterinaire canadienne
ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 49
Issue: 5
Pages: 494-498

Researcher Affiliations

Arroyo, Luis G
  • Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1. larroyo@uoguelph.ca
Vengust, Modest
    Dobson, Howard
      Viel, Laurent

        MeSH Terms

        • Animals
        • Animals, Newborn
        • Chlorides / blood
        • Fluid Therapy / veterinary
        • Horse Diseases / diagnosis
        • Horse Diseases / pathology
        • Horse Diseases / therapy
        • Horses
        • Hyponatremia / veterinary
        • Kidney / diagnostic imaging
        • Male
        • Pseudohypoaldosteronism / diagnosis
        • Pseudohypoaldosteronism / pathology
        • Pseudohypoaldosteronism / therapy
        • Pseudohypoaldosteronism / veterinary
        • Treatment Outcome
        • Ultrasonography
        • Water-Electrolyte Balance / physiology
        • Water-Electrolyte Imbalance / etiology
        • Water-Electrolyte Imbalance / veterinary

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