The cosmopolitan maternal heritage of the Thoroughbred racehorse breed shows a significant contribution from British and Irish native mares.
Abstract: The paternal origins of Thoroughbred racehorses trace back to a handful of Middle Eastern stallions, imported to the British Isles during the seventeenth century. Yet, few details of the foundation mares were recorded, in many cases not even their names (several different maternal lineages trace back to 'A Royal Mare'). This has fuelled intense speculation over their origins. We examined mitochondrial DNA from 1929 horses to determine the origin of Thoroughbred foundation mares. There is no evidence to support exclusive Arab maternal origins as some historical records have suggested, or a significant importation of Oriental mares (the term used in historic records to refer to Middle East and western Asian breeds including Arab, Akhal-Teke, Barb and Caspian). Instead, we show that Thoroughbred foundation mares had a cosmopolitan European heritage with a far greater contribution from British and Irish Native mares than previously recognized.
Publication Date: 2010-10-06 PubMed ID: 20926431PubMed Central: PMC3061175DOI: 10.1098/rsbl.2010.0800Google Scholar: Lookup
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- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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This research article investigates the maternal origins of Thoroughbred racehorses, indicating a significant contribution from British and Irish native mares, contrary to common assumptions of exclusive Middle Eastern ancestry.
Study Approach
- The researchers studied the mitochondrial DNA from 1929 horses to trace back the origins of Thoroughbred foundation mares.
- Through this genetic study, they aimed at addressing the lack of historic records about the origins of Thoroughbred mares, particularly since most of these records did not even contain the mares’ names.
Speculations Debunked
- The study found no evidence to support historical claims suggesting exclusive Arab maternal origins for Thoroughbreds, a presumption likely influenced by the known Middle Eastern origin of their paternal lineage.
- Likewise, the study could not confirm significant importation of Oriental mares, a term used historically to refer to breeds from the Middle East and Western Asia, including Arab, Akhal-Teke, Barb, and Caspian horses.
New Insights
- Opposite to initial assumptions, the research revealed that Thoroughbred foundation mares instead had a cosmopolitan European heritage.
- Particularly, a greater contribution from British and Irish Native mares to the Thoroughbred lineage was identified, a fact previously unrecognized by existing recorded histories of the breed’s ancestry.
Cite This Article
APA
Bower MA, Campana MG, Whitten M, Edwards CJ, Jones H, Barrett E, Cassidy R, Nisbet RE, Hill EW, Howe CJ, Binns M.
(2010).
The cosmopolitan maternal heritage of the Thoroughbred racehorse breed shows a significant contribution from British and Irish native mares.
Biol Lett, 7(2), 316-320.
https://doi.org/10.1098/rsbl.2010.0800 Publication
Researcher Affiliations
- McDonald Institute for Archaeological Research, University of Cambridge, Cambridge, UK. mab1004@cam.ac.uk
MeSH Terms
- Animals
- Breeding
- DNA, Mitochondrial / chemistry
- Female
- Gene Frequency
- Genetic Variation
- Haplotypes
- Horses / genetics
- Ireland
- Male
- Middle East
- Pedigree
- United Kingdom
References
This article includes 24 references
- Cassidy R. The sport of kings: kinship, class and thoroughbred breeding in Newmarket. .
- Hewitt A. Sire lines. .
- Montgomery E S. The thoroughbred. .
- Prior C M. Early records of the Thoroughbred horse. .
- Rasmussen L, Faversham R. Inbreeding to superior females: using the Rasmussen Factor to produce better racehorses. .
- Harrison SP, Turrion-Gomez JL. Mitochondrial DNA: an important female contribution to thoroughbred racehorse performance.. Mitochondrion 2006 Apr;6(2):53-63.
- Wentworth L. Thoroughbred racing stock. .
- Wallace J. The horse of America in his derivation, history and development. .
- Landry D. Noble brutes: how eastern horses transformed English culture. .
- Hill EW, Bradley DG, Al-Barody M, Ertugrul O, Splan RK, Zakharov I, Cunningham EP. History and integrity of thoroughbred dam lines revealed in equine mtDNA variation.. Anim Genet 2002 Aug;33(4):287-94.
- Jansen T, Forster P, Levine MA, Oelke H, Hurles M, Renfrew C, Weber J, Olek K. Mitochondrial DNA and the origins of the domestic horse.. Proc Natl Acad Sci U S A 2002 Aug 6;99(16):10905-10.
- McGahern A, Bower MA, Edwards CJ, Brophy PO, Sulimova G, Zakharov I, Vizuete-Forster M, Levine M, Li S, MacHugh DE, Hill EW. Evidence for biogeographic patterning of mitochondrial DNA sequences in Eastern horse populations.. Anim Genet 2006 Oct;37(5):494-7.
- Lei CZ, Su R, Bower MA, Edwards CJ, Wang XB, Weining S, Liu L, Xie WM, Li F, Liu RY, Zhang YS, Zhang CM, Chen H. Multiple maternal origins of native modern and ancient horse populations in China.. Anim Genet 2009 Dec;40(6):933-44.
- Bandelt HJ, Forster P, Röhl A. Median-joining networks for inferring intraspecific phylogenies.. Mol Biol Evol 1999 Jan;16(1):37-48.
- Larson G, Dobney K, Albarella U, Fang M, Matisoo-Smith E, Robins J, Lowden S, Finlayson H, Brand T, Willerslev E, Rowley-Conwy P, Andersson L, Cooper A. Worldwide phylogeography of wild boar reveals multiple centers of pig domestication.. Science 2005 Mar 11;307(5715):1618-21.
- Edwards CJ, Bollongino R, Scheu A, Chamberlain A, Tresset A, Vigne JD, Baird JF, Larson G, Ho SY, Heupink TH, Shapiro B, Freeman AR, Thomas MG, Arbogast RM, Arndt B, Bartosiewicz L, Benecke N, Budja M, Chaix L, Choyke AM, Coqueugniot E, Döhle HJ, Göldner H, Hartz S, Helmer D, Herzig B, Hongo H, Mashkour M, Ozdogan M, Pucher E, Roth G, Schade-Lindig S, Schmölcke U, Schulting RJ, Stephan E, Uerpmann HP, Vörös I, Voytek B, Bradley DG, Burger J. Mitochondrial DNA analysis shows a Near Eastern Neolithic origin for domestic cattle and no indication of domestication of European aurochs.. Proc Biol Sci 2007 Jun 7;274(1616):1377-85.
- Excoffier L, Smouse PE, Quattro JM. Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data.. Genetics 1992 Jun;131(2):479-91.
- Excoffier L, Laval G, Schneider S. Arlequin (version 3.0): an integrated software package for population genetics data analysis.. Evol Bioinform Online 2007 Feb 23;1:47-50.
- Jombart T. adegenet: a R package for the multivariate analysis of genetic markers.. Bioinformatics 2008 Jun 1;24(11):1403-5.
- Tamura K, Dudley J, Nei M, Kumar S. MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0.. Mol Biol Evol 2007 Aug;24(8):1596-9.
- Debevec EM, Gates RB, Masuda M, Pella J, Reynolds J, Seeb LW. SPAM (version 3.2): statistics program for analyzing mixtures.. J Hered 2000 Nov-Dec;91(6):509-10.
- Park M, Lee J W, Kim C. Correspondence analysis approach for finding allele associations in population genetic study. Comput. Statist. Data Anal. 51, 3145–3155.
- Hendricks B L. International encyclopedia of horse breeds. .
- Luís C, Bastos-Silveira C, Cothran EG, Oom Mdo M. Iberian origins of New World horse breeds.. J Hered 2006 Mar-Apr;97(2):107-13.
Citations
This article has been cited 24 times.- Lindsay-McGee V, Sanchez-Molano E, Banos G, Clark EL, Piercy RJ, Psifidi A. Genetic characterisation of the Connemara pony and the Warmblood horse using a within-breed clustering approach.. Genet Sel Evol 2023 Aug 17;55(1):60.
- Tozaki T, Ohnuma A, Kikuchi M, Ishige T, Kakoi H, Hirota KI, Takahashi Y, Nagata SI. Short Insertion and Deletion Discoveries via Whole-Genome Sequencing of 101 Thoroughbred Racehorses.. Genes (Basel) 2023 Mar 3;14(3).
- Han H, McGivney BA, Allen L, Bai D, Corduff LR, Davaakhuu G, Davaasambuu J, Dorjgotov D, Hall TJ, Hemmings AJ, Holtby AR, Jambal T, Jargalsaikhan B, Jargalsaikhan U, Kadri NK, MacHugh DE, Pausch H, Readhead C, Warburton D, Dugarjaviin M, Hill EW. Common protein-coding variants influence the racing phenotype in galloping racehorse breeds.. Commun Biol 2022 Dec 13;5(1):1320.
- Schrurs C, Blott S, Dubois G, Van Erck-Westergren E, Gardner DS. Locomotory Profiles in Thoroughbreds: Peak Stride Length and Frequency in Training and Association with Race Outcomes.. Animals (Basel) 2022 Nov 24;12(23).
- Lee J, Shin D, Kim H. National genomic evaluation of Korean thoroughbreds through indirect racing phenotype.. Anim Biosci 2022 May;35(5):659-669.
- Tozaki T, Ohnuma A, Kikuchi M, Ishige T, Kakoi H, Hirota KI, Kusano K, Nagata SI. Rare and common variant discovery by whole-genome sequencing of 101 Thoroughbred racehorses.. Sci Rep 2021 Aug 6;11(1):16057.
- Winton CL, McMahon R, Hegarty MJ, McEwan NR, Davies-Morel MCG, Morgan C, Nash DM. Genetic diversity within and between British and Irish breeds: The maternal and paternal history of native ponies.. Ecol Evol 2020 Feb;10(3):1352-1367.
- McGivney BA, Han H, Corduff LR, Katz LM, Tozaki T, MacHugh DE, Hill EW. Genomic inbreeding trends, influential sire lines and selection in the global Thoroughbred horse population.. Sci Rep 2020 Jan 16;10(1):466.
- Rooney MF, Hill EW, Kelly VP, Porter RK. The "speed gene" effect of myostatin arises in Thoroughbred horses due to a promoter proximal SINE insertion.. PLoS One 2018;13(10):e0205664.
- Tozaki T, Karasawa K, Minamijima Y, Ishii H, Kikuchi M, Kakoi H, Hirota KI, Kusano K, Nagata SI. Detection of phosphorothioated (PS) oligonucleotides in horse plasma using a product ion (m/z 94.9362) derived from the PS moiety for doping control.. BMC Res Notes 2018 Oct 29;11(1):770.
- Tozaki T, Gamo S, Takasu M, Kikuchi M, Kakoi H, Hirota KI, Kusano K, Nagata SI. Digital PCR detection of plasmid DNA administered to the skeletal muscle of a microminipig: a model case study for gene doping detection.. BMC Res Notes 2018 Oct 10;11(1):708.
- Yoon SH, Lee W, Ahn H, Caetano-Anolles K, Park KD, Kim H. Origin and spread of Thoroughbred racehorses inferred from complete mitochondrial genome sequences: Phylogenomic and Bayesian coalescent perspectives.. PLoS One 2018;13(9):e0203917.
- Tozaki T, Kikuchi M, Kakoi H, Hirota KI, Nagata SI. A genome-wide association study for body weight in Japanese Thoroughbred racehorses clarifies candidate regions on chromosomes 3, 9, 15, and 18.. J Equine Sci 2017;28(4):127-134.
- Rooney MF, Porter RK, Katz LM, Hill EW. Skeletal muscle mitochondrial bioenergetics and associations with myostatin genotypes in the Thoroughbred horse.. PLoS One 2017;12(11):e0186247.
- Miyata H, Itoh R, Sato F, Takebe N, Hada T, Tozaki T. Effect of Myostatin SNP on muscle fiber properties in male Thoroughbred horses during training period.. J Physiol Sci 2018 Sep;68(5):639-646.
- Tozaki T, Kikuchi M, Kakoi H, Hirota KI, Mukai K, Aida H, Nakamura S, Nagata SI. Profiling of exercise-induced transcripts in the peripheral blood cells of Thoroughbred horses.. J Equine Sci 2016;27(4):157-164.
- Tozaki T, Sato F, Ishimaru M, Kikuchi M, Kakoi H, Hirota KI, Nagata SI. Sequence variants of BIEC2-808543 near LCORL are associated with body composition in Thoroughbreds under training.. J Equine Sci 2016;27(3):107-114.
- Petersen JL, Valberg SJ, Mickelson JR, McCue ME. Haplotype diversity in the equine myostatin gene with focus on variants associated with race distance propensity and muscle fiber type proportions.. Anim Genet 2014 Dec;45(6):827-35.
- Boyko AR, Brooks SA, Behan-Braman A, Castelhano M, Corey E, Oliveira KC, Swinburne JE, Todhunter RJ, Zhang Z, Ainsworth DM, Robinson NE. Genomic analysis establishes correlation between growth and laryngeal neuropathy in Thoroughbreds.. BMC Genomics 2014 Apr 3;15:259.
- Devi KM, Ghosh SK. Molecular phylogeny of Indian horse breeds with special reference to Manipuri pony based on mitochondrial D-loop.. Mol Biol Rep 2013 Oct;40(10):5861-7.
- Wallner B, Vogl C, Shukla P, Burgstaller JP, Druml T, Brem G. Identification of genetic variation on the horse y chromosome and the tracing of male founder lineages in modern breeds.. PLoS One 2013;8(4):e60015.
- Petersen JL, Mickelson JR, Cothran EG, Andersson LS, Axelsson J, Bailey E, Bannasch D, Binns MM, Borges AS, Brama P, da Câmara Machado A, Distl O, Felicetti M, Fox-Clipsham L, Graves KT, Guérin G, Haase B, Hasegawa T, Hemmann K, Hill EW, Leeb T, Lindgren G, Lohi H, Lopes MS, McGivney BA, Mikko S, Orr N, Penedo MC, Piercy RJ, Raekallio M, Rieder S, Røed KH, Silvestrelli M, Swinburne J, Tozaki T, Vaudin M, M Wade C, McCue ME. Genetic diversity in the modern horse illustrated from genome-wide SNP data.. PLoS One 2013;8(1):e54997.
- Achilli A, Olivieri A, Soares P, Lancioni H, Hooshiar Kashani B, Perego UA, Nergadze SG, Carossa V, Santagostino M, Capomaccio S, Felicetti M, Al-Achkar W, Penedo MC, Verini-Supplizi A, Houshmand M, Woodward SR, Semino O, Silvestrelli M, Giulotto E, Pereira L, Bandelt HJ, Torroni A. Mitochondrial genomes from modern horses reveal the major haplogroups that underwent domestication.. Proc Natl Acad Sci U S A 2012 Feb 14;109(7):2449-54.
- Bower MA, McGivney BA, Campana MG, Gu J, Andersson LS, Barrett E, Davis CR, Mikko S, Stock F, Voronkova V, Bradley DG, Fahey AG, Lindgren G, MacHugh DE, Sulimova G, Hill EW. The genetic origin and history of speed in the Thoroughbred racehorse.. Nat Commun 2012 Jan 24;3:643.
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