The D(+) xylose absorption test in the horse.
Abstract: SUMMARY
A D(+) xylose absorption test has been standardised for use in the horse. A dose of 2 g. xylose/Kg. body-weight is required to produce a maximum plasma xylose level of 30 mg./100ml. after two hours. There are limitations to the procedure being used as a routine clinical screening test of small intestinal dysfunction in the horse.
RÉSUMÉ
On a standardisé un test d'absorption du D(+) xylose pour le cheval.
Une dose de 2 gr de xylose par kilo de poids vif est nécessaire pour produire une élevation du xylose plasmatique jusqu'à 30 mg par 100 ml après deux heures.
Il y a des limitations à l'emploi de cette méthode pour l'exploration de routine des dysfonctionnements de l'intestin grele chez le cheval.
ZUSAMMENFASSUNG
Ein D(+)Xylose-Absorptionstest wurde für die Verwendung beim Pferd standardisiert. Eine Dosis von 2 g. Xylose/kg. Körpergewicht wird benötigt, um eine maximale Plasmakonzentration von 30 mg./100 ml. nach 2 Stunden zu erreichen. Die Grenze des Tests für den routinemässigen Einsatz als Screening-Test für Dünndarmdysfunktionen beim Pferd werden aufgezeigt.
Publication Date: 1974-01-01 PubMed ID: 4819828DOI: 10.1111/j.2042-3306.1974.tb03924.xGoogle Scholar: Lookup
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- Journal Article
Summary
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This research article focuses on the standardization of a D(+) xylose absorption test specifically for horses. While it has potential to be used as a routine clinical screening for small intestinal dysfunction in horses, the research recognizes certain limitations to this application.
The D(+) Xylose Absorption Test
- The research has been carried out to standardize a D(+) xylose absorption test used in horses. This test involves giving a specified amount of xylose, a simple sugar, to a horse and observing its absorption in the horse’s body.
- The researchers found that a dose of 2 grams of xylose per kilogram of body weight is necessary to produce a peak blood xylose concentration of 30 milligrams per 100 milliliters two hours after administration. The study thus provides a standard protocol for conducting this test in horses by defining the dose of xylose to be used and the expected outcome.
Potential Use for the Test
- The main potential use of the D(+) xylose absorption test as identified by the research is in the routine clinical screening of small intestinal dysfunction in horses. Intestinal dysfunction in horses can lead to severe health problems such as colic, and early detection through a routine test like this could result in earlier and more effective interventions.
Limitations to the Procedure
- However, the research also recognises that there are some limitations to using this test as a routine screening procedure. Although the specifics of these limitations are not detailed in the abstract, they could relate to practical issues such as the cost or complexity of the test, or other scientific factors like the potential for false positive or negative results.
Cite This Article
APA
Roberts MC.
(1974).
The D(+) xylose absorption test in the horse.
Equine Vet J, 6(1), 28-30.
https://doi.org/10.1111/j.2042-3306.1974.tb03924.x Publication
Researcher Affiliations
MeSH Terms
- Administration, Oral
- Animals
- Female
- Glucose Tolerance Test
- Horses / metabolism
- Intestinal Absorption
- Male
- Xylose / administration & dosage
- Xylose / blood
- Xylose / metabolism
Citations
This article has been cited 2 times.- Kaikkonen R, Niinistö K, Sykes B, Anttila M, Sankari S, Raekallio M. Diagnostic evaluation and short-term outcome as indicators of long-term prognosis in horses with findings suggestive of inflammatory bowel disease treated with corticosteroids and anthelmintics.. Acta Vet Scand 2014 Jun 3;56(1):35.
- Ijaz MK, Sabara MI, Frenchick PJ, Babiuk LA. Assessment of intestinal damage in rotavirus infected neonatal mice by a D-xylose absorption test.. J Virol Methods 1987 Nov;18(2-3):153-7.
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