[The diagnostic value of venous blood gas parameters and pH value in newborn foals with pulmonary diseases].
Abstract: Analysis of blood gases in equine neonatology is regarded as a diagnostic tool to study the neonatal adaptation period. Aim of this study therefore was to compare the diagnostic value of venous blood gas parameters to arterial parameters in newborn foals with pulmonary disorders. Venous as well as arterial blood samples were taken from 24 foals (1 to 6 days old) and the partial pressure of oxygen (pO2), partial pressure of carbon dioxide (pCO2), pH, and oxygen parturition (S-O2) of these samples were investigated. In addition, the alveolar (A) to arterial (a) gradients (A-aDO2) were calculated. Due to changes in blood gas parameters during the first week postnatal the age was taken into consideration by using covariance analysis. All arterial parameters except paCO2 showed a significant difference among healthy foals (n = 15) and foals with respiratory disorders (n = 11) with A-aDO2 and paO2 being the most reliable arterial parameters. In venous blood there was a significant difference between healthy and sick foals only in S-O2 and pH.
Publication Date: 2001-06-21 PubMed ID: 11413714
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- Comparative Study
- English Abstract
- Journal Article
Summary
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This research paper examines the diagnostic value of venous blood gas parameters for identifying pulmonary disorders in newborn foals. The study demonstrates that there are significant differences between the blood gas parameters of healthy foals and foals with respiratory issues.
Research Methodology
- The study took blood samples from 24 newborn foals ranging between 1 to 6 days old.
- Both venous and arterial blood were tested for partial pressure of oxygen (pO2), partial pressure of carbon dioxide (pCO2), pH, and oxygen parturition (S-O2).
- The study also calculated the alveolar (A) to arterial (a) gradients (A-aDO2).
- Due to changes in blood gas parameters during the first week of a foal’s life, the age of the foal was also considered during the analysis.
Findings
- Arterial blood gas parameters, with the exception of paCO2, showed significant differences between healthy foals and those with respiratory disorders.
- A-aDO2 and paO2 were identified as the most reliable arterial parameters to differentiate between healthy and sick foals.
- For venous blood, only S-O2 and pH showed significant variations between healthy and sick foals.
Implications
- This research suggests that arterial blood gas parameters, specifically A-aDO2 and paO2, are crucial indicators of respiratory disorders in neonatal foals.
- The study also points out the potential importance of S-O2 and pH levels in venous blood as potential diagnostic indicators for these disorders.
Limitations
- The sample size of the study was limited to 24 foals, and the analysis was constrained by the variations in blood gas parameters during the first week after birth.
Cite This Article
APA
Hauser B, Wehrend A, Bostedt H, Failing K.
(2001).
[The diagnostic value of venous blood gas parameters and pH value in newborn foals with pulmonary diseases].
Berl Munch Tierarztl Wochenschr, 114(5-6), 197-201.
Publication
Researcher Affiliations
- Klinik für Geburtshilfe, Gynäkologie und Andrologie der Gross- und Kleintiere mit Tierärztlicher Ambulanz, Justus-Liebig-Universität Giessen.
MeSH Terms
- Animals
- Animals, Newborn / blood
- Blood Gas Analysis / veterinary
- Carbon Dioxide / blood
- Horse Diseases / blood
- Horse Diseases / diagnosis
- Horses / blood
- Hydrogen-Ion Concentration
- Lung Diseases / blood
- Lung Diseases / diagnosis
- Lung Diseases / veterinary
- Oxygen / blood
- Partial Pressure
- Reference Values
Citations
This article has been cited 1 times.- Osman T, Probo M, Monaco D, Shafiek HK, Freccero F. Blood Gas, Acid-Base and Electrolyte Analysis in Healthy Dromedary Camel Calves up to 21 Days of Life. Animals (Basel) 2023 Mar 22;13(6).
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