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Home / Equine Research Bank / Vet Surg / The effect of cyanoacrylate on knot elongation in three sutu...
Veterinary surgery : VS2023; 52(3); 428-434; doi: 10.1111/vsu.13936

The effect of cyanoacrylate on knot elongation in three sutures used for prosthetic laryngoplasty in the horse.

Abstract: This study investigated the elongation following cyclic loading on square knots of 5 USP multifilament long-chain ultra-high molecular weight polyethylene core (UHMWPE), 2 mm woven UHMWPE tape, and 5 USP braided polyester, with and without cyanoacrylate glue. Methods: Experimental study. Methods: n = 4. Methods: Three conditions (suture without knot, suture with knot, suture with knot + cyanoacrylate) were evaluated for each suture material on a mechanical test stand by measuring the increased length of the construct after cycling from 25 to 50N for 1000 repetitions at 20 mm/second. Knot elongation was determined by subtracting the length of the control suture from the suture with knot or suture with knot + cyanoacrylate. The data were analyzed with a linear regression model with robust estimation of variance. Post-hoc analysis determined the model adjusted differences (square knot vs. cyanoacrylate) as a difference from control. t-tests were conducted to identify the significant findings. Results: Total elongation of polyester (6.2-7.8 mm) was greater than multifilament UHMWPE (3.4-6.4 mm) and UHMWPE tape (2-3.7 mm) for all conditions. Polyester had the lowest knot elongation (1.6 mm) and the addition of cyanoacrylate decreased knot elongation for polyester by 1 mm. Conclusions: Polyester had the most total construct elongation followed by multifilament UHMWPE and UHMWPE tape. Polyester showed the least knot elongation and cyanoacrylate decreased this knot elongation. Conclusions: Total construct and knot elongation should be considered as contributing factors to loss of arytenoid abduction following prosthetic laryngoplasty when using polyester, multifilament UHMWPE, or UHMWPE tape. Addition of cyanoacrylate to polyester knots should be explored to limit elongation.
© 2023 American College of Veterinary Surgeons.
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Publication Date: 2023-01-24 PubMed ID: 36691965DOI: 10.1111/vsu.13936Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This study compares elongation in three types of sutures used for prosthetic laryngoplasty in horses— multifilament ultra-high molecular weight polyethylene (UHMWPE), woven UHMWPE tape, and braided polyester—with and without cyanoacrylate glue, under conditions of repeated mechanical stress.

Study Design and Methodology

  • The study used an experimental design with each run-through comprising three conditions: suture without knot, suture with knot, and suture with knot plus cyanoacrylate.
  • These three conditions were tested for each of the three suture materials on a mechanical stand, with the increased length of the construct measured after being cycled from 25N to 50N for 1000 repetitions at a speed of 20 mm/second.
  • Knot elongation was then determined by subtracting the length of the control suture (without knot) from the suture with knot or suture with knot plus cyanoacrylate.
  • The data were then analyzed using a linear regression model with robust estimation of variance, with post-hoc analysis determining model adjusted differences. t-tests were conducted to ascertain significant findings.

Findings

  • The total elongation observed was greatest for polyester (6.2-7.8 mm) compared to multifilament UHMWPE (3.4-6.4 mm) and UHMWPE tape (2-3.7 mm) for all conditions.
  • Polyester demonstrated the lowest knot elongation at 1.6 mm and also showed the greatest decrease in knot elongation when cyanoacrylate was added, reducing elongation by 1 mm.

Conclusions

  • Accordingly, polyester had the most total construct elongation, followed by multifilament UHMWPE, and UHMWPE tape. It also exhibited the least knot elongation, a figure that was decreased even further with the addition of cyanoacrylate.
  • The authors concluded that both these factors should be considered as contributing factors to the loss of arytenoid abduction following prosthetic laryngoplasty when using polyester, multifilament UHMWPE, or UHMWPE tape sutures.
  • In light of these results, they recommended further exploration into the use of cyanoacrylate on polyester knots to limit elongation.

Cite This Article

APA
Watkins AR, Ford M, van Eps AW, Stefanovski D, Parente EJ. (2023). The effect of cyanoacrylate on knot elongation in three sutures used for prosthetic laryngoplasty in the horse. Vet Surg, 52(3), 428-434. https://doi.org/10.1111/vsu.13936

Publication

Veterinary surgery : VS
ISSN: 1532-950X
NlmUniqueID: 8113214
Country: United States
Language: English
Volume: 52
Issue: 3
Pages: 428-434

Researcher Affiliations

Watkins, Amanda R
  • University of Pennsylvania New Bolton Center, Kennett Square, Pennsylvania, USA.
Ford, Matt
  • University of Pennsylvania New Bolton Center, Kennett Square, Pennsylvania, USA.
van Eps, Andrew W
  • University of Pennsylvania New Bolton Center, Kennett Square, Pennsylvania, USA.
Stefanovski, Darko
  • University of Pennsylvania New Bolton Center, Kennett Square, Pennsylvania, USA.
Parente, Eric J
  • University of Pennsylvania New Bolton Center, Kennett Square, Pennsylvania, USA.

MeSH Terms

  • Horses / surgery
  • Animals
  • Cyanoacrylates / therapeutic use
  • Laryngoplasty / veterinary
  • Suture Techniques / veterinary
  • Tensile Strength
  • Polyesters
  • Sutures / veterinary
  • Materials Testing / veterinary

Grant Funding

  • 580-5805-1-400666-5340-2000-5887 / Raker-Tulleners Endowed Fund

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Citations

This article has been cited 1 times.
  1. Ysebaert MP, Johnson J, Marie U, Campos A, Verchrerin A, Ducharme NG, Rossignol F, Luedke LK. Biomechanical testing of three constructs for prosthetic laryngoplasty in horses demonstrates advantages of differing metallic implants in the arytenoid cartilage. Vet Surg 2026 Jan;55(1):69-77.
    doi: 10.1111/vsu.14328pubmed: 40785216google scholar: lookup
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