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Home / Equine Research Bank / Pflugers Arch / The effect of high-intensity exercise on the respiratory cap...
Pflugers Archiv : European journal of physiology1990; 415(4); 407-413; doi: 10.1007/BF00373617

The effect of high-intensity exercise on the respiratory capacity of skeletal muscle.

Abstract: The effect of high-intensity exercise on the respiratory capacity of skeletal muscle was studied in horses which ran five 600-m bouts on a track with 2 min of rest between exercise bouts, or once to fatigue on a treadmill at an intensity that elicited the maximal oxygen uptake. Venous blood and biopsy samples of the middle gluteal muscle were collected at rest, after each exercise bout, and 30 and 60 min post-exercise. Blood samples were analyzed for lactate concentration and pH and muscle samples for metabolites, pH, and respiratory capacity. Venous blood and muscle pH declined to 6.91 +/- 0.02 and 6.57 +/- 0.02, respectively, after the fifth track run and to 6.98 +/- 0.02 and 6.71 +/- 0.07, respectively, after treadmill running. Muscle metabolite changes were consistent with the metabolic response to high-intensity exercise. Muscle respiratory capacity declined greater than 20% (P less than 0.05) after a single exercise bout and was 45% of the control value after the fifth track run. Tissue respiration was depressed 60 min post-exercise but was normal 24 h later. These observations suggest that high-intensity exercise impairs the respiratory capacity of the working muscle. Although this occurred in parallel with reductions in pH, other factors could be responsible for this response.
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Publication Date: 1990-01-01 PubMed ID: 2315003DOI: 10.1007/BF00373617Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research explores the impacts of high-intensity exercise on the respiratory capacity of skeletal muscle, highlighting how such exercise performs in horses can reduce this capacity significantly.

Background and Methodology

  • The study was focused on examining the impact of high-intensity exercise on the respiratory capacity of skeletal muscles.
  • Two kinds of exercises were investigated: five 600-m track bouts with 2-min rests between them and a single run to fatigue on a treadmill at a maximum oxygen uptake level.
  • The subjects of this experiment were horses, and both venous blood and biopsy samples of the middle gluteal muscle were taken at different points before, during, and after the exercise.

Findings Observations

  • After conducting the exercises and analyzing the collected samples, researchers found that venous blood and muscle pH significantly dropped.
  • The five rounds of high-intensity track running led to more accentuated declines in pH levels in both venous blood and muscle compared to the treadmill run.
  • Changes in muscle metabolite were also noticed, and those were in line with the expected metabolic response to high-intensity exercise.
  • Notably, a single bout of exercise led to a greater than 20% decline in muscle respiratory capacity, with this figure rising to 45% after the fifth track run.

Interpretations and Implications

  • These findings suggest that high-intensity exercise can impair the respiratory capacity of the muscles involved in the exercise, with the impact apparently proportional to the intensity of the exercise.
  • Though these effects seemed to occur together with reductions in pH, the researchers acknowledged that other factors might contribute to the reduction in the respiratory capacity of skeletal muscles during high-intensity exercise.
  • The capacity declined significantly immediately after the exercise (60 minutes later) but was back to normal 24 hours after exercise, suggesting that the effect is temporary and timebound.

Cite This Article

APA
Gollnick PD, Bertocci LA, Kelso TB, Witt EH, Hodgson DR. (1990). The effect of high-intensity exercise on the respiratory capacity of skeletal muscle. Pflugers Arch, 415(4), 407-413. https://doi.org/10.1007/BF00373617

Publication

Pflugers Archiv : European journal of physiology
ISSN: 0031-6768
NlmUniqueID: 0154720
Country: Germany
Language: English
Volume: 415
Issue: 4
Pages: 407-413

Researcher Affiliations

Gollnick, P D
  • Department of Veterinary and Comparative Anatomy, Washington State University, Pullman 99164-6520.
Bertocci, L A
    Kelso, T B
      Witt, E H
        Hodgson, D R

          MeSH Terms

          • Animals
          • Female
          • Horses / physiology
          • Male
          • Mitochondria, Muscle / metabolism
          • Muscles / metabolism
          • Muscles / physiology
          • Oxygen Consumption / physiology
          • Physical Exertion / physiology

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          Citations

          This article has been cited 10 times.
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