The effect of the interval from PGF treatment to ovulation on embryo recovery and pregnancy rate in the mare.
Abstract: The objective of this study was to determine the effect of the interval from induced luteolysis to ovulation on fertility of mares from two different farms. At farm 1, 215 mares were inseminated with frozen/thawed semen during 513 estrous cycles over seven consecutive breeding seasons. Estrus was induced with analogues of PGF2α in 179 cycles. At farm 2, 375 embryo flushings were performed in 65 donor mares inseminated with fresh semen; of which, 327 were performed following artificial insemination after PGF-induced luteolysis. In both farms, the intervals from PGF treatment to ovulation (ITO) data were divided into three interval groups: less than 6 days, 6 to 8 days, and greater than 8 days. A mixed regression model was created to determine the effect of different factors on the pregnancy rate (PR) and embryo recovery rate (ERR). Of all factors analyzed, the ITO was the only one that significantly influenced the PR and ERR (P < 0.05). In farm 1, the PR of mares with an ITO of less than 6 days, 6 to 8 days, and greater than 8 days was 26.6%, 39.4%, and 55.9%, respectively (P = 0.01). The PR for mares inseminated after spontaneous luteolysis (without PGF) was 42.5%. In farm 2, the ERR of donor mares for the same ITO groups was 55.0%, 62.6%, and 73.7%, respectively (P = 0.02). The ERR for mares flushed after a previous spontaneous estrus was 75.0%. In conclusion, the ITO had a significant effect on the PR and ERR in the mare. Fertility was reduced as the ITO became shorter.
Copyright © 2015 Elsevier Inc. All rights reserved.
Publication Date: 2015-01-16 PubMed ID: 25666044DOI: 10.1016/j.theriogenology.2015.01.010Google Scholar: Lookup
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- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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The research evaluates the impact of the time interval between the application of Prostaglandin (PGF) treatment and ovulation on the fertility rates of mares (female horses) in two different farms. The study, carried out over seven breeding seasons, deduces that a shorter interval between PGF treatment and ovulation tends to reduce fertility.
Research Methodology
- The study was conducted in two separate farms covering 513 estrous cycles of 215 mares on farm 1 and 375 embryo flushing procedures in 65 donor mares on farm 2.
- For artificial insemination, frozen/thawed semen was used on farm 1, while fresh semen was used on farm 2.
- Prostaglandin (PGF2α) analogues were used to induce estrus in 179 out of the overall cycles on farm 1, and artificial insemination following PGF-induced luteolysis was applied in 327 cycles on farm 2.
Results and Analysis
- Data from the two farms was divided into three groups based on the interval from PGF treatment to ovulation (ITO): less than 6 days, 6 to 8 days, and greater than 8 days.
- A regression model was used to analyze the effect of various factors on both pregnancy rate (PR) and embryo recovery rate (ERR) of the mares.
- Out of all factors, the ITO was the one to induce significant influence on both ERR and PR, as indicated with a P value less than 0.05.
- In Farm 1, mares with an ITO of less than 6 days, 6-8 days, and more than 8 days were observed to have PRs of 26.6%, 39.4%, and 55.9% respectively. The mares which were inseminated post spontaneous luteolysis (without PGF treatment) recorded a PR of 42.5%.
- In Farm 2, mares with the same ITO groups had ERRs of 55.%, 62.6%, and 73.7% respectively. Mares flushed after a spontaneous estrus had an ERR of 75%.
Conclusion
- The time interval between PGF treatment and ovulation had a significant impact on both ERR and PR in mares, with a shorter ITO reducing fertility rates.
Cite This Article
APA
Cuervo-Arango J, Mateu-Sánchez S, Aguilar JJ, Nielsen JM, Etcharren V, Vettorazzi ML, Newcombe JR.
(2015).
The effect of the interval from PGF treatment to ovulation on embryo recovery and pregnancy rate in the mare.
Theriogenology, 83(8), 1272-1278.
https://doi.org/10.1016/j.theriogenology.2015.01.010 Publication
Researcher Affiliations
- Departamento de Medicina y Cirugía Animal, Facultad de Veterinaria, Universidad CEU Cardenal Herrera, Valencia, Spain. Electronic address: juan.cuervo@uch.ceu.es.
- Departamento de Medicina y Cirugía Animal, Facultad de Veterinaria, Universidad CEU Cardenal Herrera, Valencia, Spain.
- Producción Equina, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto, Córdoba, Argentina.
- Ansager Dyrehospital, Ansager, Denmark.
- Producción Equina, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto, Córdoba, Argentina.
- Producción Equina, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto, Córdoba, Argentina.
- Warren House Farm, Equine Fertility Clinic, Brownhills, West Midlands, UK.
MeSH Terms
- Animals
- Embryo Transfer
- Female
- Horses / physiology
- Insemination, Artificial / veterinary
- Luteolysis / drug effects
- Ovarian Follicle / anatomy & histology
- Ovulation / drug effects
- Ovulation Induction / methods
- Ovulation Induction / veterinary
- Pregnancy
- Pregnancy Rate
- Pregnancy, Multiple
- Prostaglandins F / administration & dosage
- Seasons
- Time Factors
- Tissue and Organ Harvesting / methods
- Tissue and Organ Harvesting / veterinary
Citations
This article has been cited 4 times.- Newcombe JR, Cuervo-Arango J, Wilsher S. The Timing of the Maternal Recognition of Pregnancy Is Specific to Individual Mares. Animals (Basel) 2023 May 22;13(10).
- Silva ESM, Newcombe JR, Cuervo-Arango J. The Effect of Treatment with Oestradiol Benzoate on Oestrus Expression and Endometrial Oedema in Anovulatory and Cyclic Mares. Animals (Basel) 2023 Mar 5;13(5).
- Rosa LC, Dias ECS, Melo RS, do Rosário CJRM, Pereira FLC, Chung LBO, da Anunciação ARA, Moraes FJ, Souza FA, Chaves RM. The ovarian and uterine responses of Baixadeiro mares to prostaglandin synchronization during the dry and rainy seasons. Anim Reprod 2022;19(1):e20200050.
- Bottrel M, Ortiz I, Hidalgo M, Díaz-Jiménez M, Pereira B, Consuegra C, Yousef MS, Dorado J. Hormonal Management for the Induction of Luteolysis and Ovulation in Andalusian Jennies: Effect on Reproductive Performance, Embryo Quality and Recovery Rate. Animals (Basel) 2022 Jan 8;12(2).
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