The evaluation of selected parameters of cellular nonspecific immunity in normal and allergic horses.

This research compares certain nonspecific immunity parameters in allergic horses and healthy horses, finding differences in cell functionality and certain test values between the two groups.

Objective of the Research

• The goal of this research was to study and differentiate the nonspecific immunity parameters of horses who have allergies from those of horses in healthy condition.

Methodology of the Study

• 14 allergic horses and 12 healthy horses were examined in order to compare their immunity parameters.
• The parameters were assessed based on the in vitro functional capacity of their phagocytic cells through the use of the nitro blue tetrazolium chloride reduction test. Both the spontaneous (NBT) and zymosan-stimulated (NBTs) versions of the test were used.
• Their ingestion capacity of phagocytic cells was gauged employing a phagocytic index test (IF), as well as the activity percentage of phagocytosing neutrophils (%KF).

Results and Findings

• Differences were indeed observed between allergic and healthy horses, particularly horses with severe allergy symptoms.
• NBTs values were higher in healthy horses compared to allergic horses.
• The phagocytic index values were found to be significantly higher in horses with allergies.

Implications of the Findings

• This research showcases the variable immunity parameters in allergic and healthy horses. The study could notably increase the understanding of how allergies impact the nonspecific immune system in horses.
• The higher phagocytic index values in allergic horses might suggest that these horses’ immune systems are working harder to fight off allergens, which could be an area for future research.
• These results could influence future horse care, providing some considerations for veterinarians dealing with horses suffering from allergies.