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Equine veterinary journal1994; 26(2); 140-142; doi: 10.1111/j.2042-3306.1994.tb04353.x

The prevalence of latent Equid herpesviruses in the tissues of 40 abattoir horses.

Abstract: Equid herpesviruses 1 or 4 (EHV-1 or -4) were isolated by cocultivation from 60% of 40 horses examined at slaughter. The lymph nodes draining the respiratory tract were the most common source of virus. EHV-1 or EHV-4 was never isolated from the trigeminal ganglia (SLG). The polymerase chain reaction (PCR) detected virus in 87.5% of bronchial lymph nodes and a similar level in the trigeminal ganglia that were examined. By both assays approximately one third of the positive animals harboured both viruses. Equid herpesvirus 2 (EHV-2) was isolated from all but one of the horses and from > 75% of the lymph nodes draining the respiratory tract; alpha viruses were isolated only in the presence of EHV-2. The results indicate that latent EHV-1 and EHV-4 are widespread in the equine population and that the primary site of latency is the lymph nodes of the respiratory tract.
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Publication Date: 1994-03-01 PubMed ID: 8575377DOI: 10.1111/j.2042-3306.1994.tb04353.xGoogle Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study investigates the widespread presence of Equid herpesviruses 1 and 4 (EHV-1 or EHV-4) in 40 horses and finds that the primary site of latency is the lymph nodes of the respiratory tract.

Objective of the Research

The research aims to discern the presence and prevalence of latent Equid herpesviruses 1 and 4 (EHV-1 or EHV-4) in horses. By analysing the tissues of 40 horses examined at slaughter, the researchers were able to ascertain the occurrence and distribution of these herpesviruses in the equine population.

Methodology

  • The researchers used co-cultivation to isolate EHV-1 or -4 from the horses.
  • The lymph nodes draining the respiratory tract were found to be the most common virus source.
  • The researchers used the Polymerase Chain Reaction (PCR) to detect the presence of theses viruses in the bronchial lymph nodes and the trigeminal ganglia.

Findings

  • EHV-1 or -4 was isolated from 60% of the 40 horses examined.
  • These viruses were never isolated from trigeminal ganglia (SLG).
  • Virus presence was detected in 87.5% of bronchial lymph nodes and a similar percentage in the trigeminal ganglia that were examined.
  • Approximately a third of the positive animals harbored both EHV-1 and EHV-4.
  • Equid herpesvirus 2 (EHV-2) was isolated from all but one of the horses and from more than 75% of the lymph nodes draining the respiratory tract.
  • Alpha viruses were isolated only in the presence of EHV-2.

Conclusion

The results of the study imply that latent EHV-1 and EHV-4 are widespread in the equine population. Moreover, the lymph nodes of the respiratory tract were identified as the primary site of latency.

Cite This Article

APA
Edington N, Welch HM, Griffiths L. (1994). The prevalence of latent Equid herpesviruses in the tissues of 40 abattoir horses. Equine Vet J, 26(2), 140-142. https://doi.org/10.1111/j.2042-3306.1994.tb04353.x

Publication

Equine veterinary journal
ISSN: 0425-1644
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 26
Issue: 2
Pages: 140-142

Researcher Affiliations

Edington, N
  • Department of Pathology and Infectious Disease, Royal Veterinary College, London, UK.
Welch, H M
    Griffiths, L

      MeSH Terms

      • Abattoirs
      • Animals
      • Antibodies, Monoclonal / analysis
      • Antibodies, Monoclonal / immunology
      • DNA, Viral / analysis
      • DNA, Viral / genetics
      • Female
      • Herpesviridae Infections / epidemiology
      • Herpesviridae Infections / veterinary
      • Herpesviridae Infections / virology
      • Herpesvirus 1, Equid / genetics
      • Herpesvirus 1, Equid / immunology
      • Herpesvirus 1, Equid / isolation & purification
      • Herpesvirus 1, Equid / physiology
      • Horse Diseases / epidemiology
      • Horse Diseases / virology
      • Horses
      • Lymph Nodes / virology
      • Male
      • Polymerase Chain Reaction
      • Prevalence
      • United Kingdom / epidemiology
      • Virus Latency

      Citations

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