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Tijdschrift voor diergeneeskunde2001; 125(24); 743-747;

[The use of electromyographic examination as a diagnostic tool and phenytoin sodium as treatment in a case of classic springhalt in a Dutch warmblood horse].

Abstract: This paper describes a case of unilateral stringhalt present for 18 months in the right hind limb of a 4-year-old Warmblood gelding. The only abnormalities detected by electromyography (EMG) were a prolonged insertion activity, fibrillation potentials, and positive waves at rest and enhanced EMG activity in the right lateral digital extensor muscle on muscle contraction. This was interpreted as denervation and hyperirritability of this muscle. Both similarities and differences with Australian stringhalt could be found. As described for horses suffering from Australian stringhalt, phenytoin sodium was administered orally in a dosage ranging from 15 to 9.3 mg/kg body weight in order to try to influence the hyperflexia. Therapeutic effects without side effects could be achieved at plasma concentrations between 5.1 and 9.9 mg/L at a dosage of 12 mg/kg body weight twice daily, which is consistent with data in the literature (5-10 mg/L). The EMG examination seems to help to clarify the aetiology of the classical form of stringhalt, since the only abnormality in this patient was an abnormal electrical activity in the lateral digital extensor muscle. As in Australian stringhalt, in this type of stringhalt phenytoin also relieved the hyperflexion of the tarsus.
Publication Date: 2001-02-24 PubMed ID: 11189905
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Summary

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The study focuses on the diagnosis and treatment of a condition known as stringhalt in a horse, using electromyographic examination as a diagnostic tool and phenytoin sodium as a treatment.

Understanding Stringhalt

  • Stringhalt is a neuromuscular disorder in horses that causes a sudden, jerking lifting of one or both of the hind legs. The consequent abnormal movement is involuntary and often happens when the horse is turning, backing up, or starting to move.
  • In this study, the particular case is of a unilateral stringhalt exhibited for 18 months in a 4-year-old Warmblood gelding’s right hind limb.

Use of Electromyography (EMG)

  • The only abnormalities detected through the EMG were a prolonged insertion activity, fibrillation potentials, and positive waves at rest. There was also enhanced EMG activity in the right lateral digital extensor muscle on muscle contraction.
  • This was interpreted as denervation (loss of nerve supply) and hyperirritability of the said muscle.
  • The study found both similarities and differences in this case with Australian stringhalt, another variant of the disorder.
  • The EMG examination was found to be helpful in clarifying the etiology (cause) of the classical form of stringhalt, as the only abnormality in this patient was an abnormal electrical activity in one specific muscle.

Phenytoin Sodium as Treatment

  • Phenytoin sodium was administered orally. The dosage varied between 15 and 9.3 mg/kg body weight in an attempt to influence the hyper-flexia (excessive flexion).
  • Therapeutic effects without any side effects were seen at plasma concentrations between 5.1 and 9.9 mg/L at a dosage of 12 mg/kg body weight given twice daily. This is in line with data referenced in other research literature that suggests effective plasma concentrations fall within the 5-10 mg/L range.
  • In this type of stringhalt, the horse was relieved of the excessive tarsal (ankle) hyperflexion by phenytoin, similar to its effect in cases of Australian stringhalt.

Cite This Article

APA
Wijnberg ID, Back W, van der Kolk JH. (2001). [The use of electromyographic examination as a diagnostic tool and phenytoin sodium as treatment in a case of classic springhalt in a Dutch warmblood horse]. Tijdschr Diergeneeskd, 125(24), 743-747.

Publication

ISSN: 0040-7453
NlmUniqueID: 0031550
Country: Netherlands
Language: dut
Volume: 125
Issue: 24
Pages: 743-747

Researcher Affiliations

Wijnberg, I D
  • Hoofdafdeling Gezondheidszorg Paard, Discipline Inwendige Ziekten, Universiteit Utrecht, Faculteit der Diergeneeskunde, Yalelaan 16, 3584 CM Utrecht.
Back, W
    van der Kolk, J H

      MeSH Terms

      • Animals
      • Electromyography / veterinary
      • Female
      • Hindlimb / physiopathology
      • Horse Diseases / diagnosis
      • Horse Diseases / drug therapy
      • Horse Diseases / physiopathology
      • Horses
      • Lameness, Animal / diagnosis
      • Lameness, Animal / drug therapy
      • Lameness, Animal / physiopathology
      • Muscle, Skeletal / physiopathology
      • Neuromuscular Agents / therapeutic use
      • Phenytoin / therapeutic use
      • Time Factors
      • Walking

      Citations

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