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The Veterinary record2017; 180(1); 14-15; doi: 10.1136/vr.j8

Theiler’s disease.

Abstract: Ben Sturgeon discusses Theiler's disease, one of the most common causes of acute hepatitis in horses.
Publication Date: 2017-01-08 PubMed ID: 28062774DOI: 10.1136/vr.j8Google Scholar: Lookup
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  • Journal Article

Summary

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This article explores Theiler’s disease, a prevalent cause of sudden liver inflammation in horses, its causes, symptoms, diagnosis methods and treatment options.

Introduction to Theiler’s Disease

  • The author begins by providing an introduction to Theiler’s disease, describing it as one of the most common causes of acute hepatitis, an inflammation of the liver, in horses.

Causes and Risk Factors

  • Ben Sturgeon goes on to review potential causes and risk factors for Theiler’s disease. The research indicates that the disease might be linked to immunizations that horses receive, including those against equine herpesvirus and equine arteritis virus.
  • These vaccinations are made with equine serum, which could contain viral particles that cause Theiler’s disease. Also, the disease can be transmitted through contaminated equipment or during operations.

Symptoms and Clinical Features

  • The article also provides detailed information about the clinical features and symptoms of Theiler’s disease. Common symptoms include jaundice, fever, swelling in the legs, confusion, and even sudden death.

Diagnosis and Management

  • The article discusses various diagnostic methods for Theiler’s disease, including blood tests, liver biopsies, and ultrasonography.
  • In terms of managing the disease, Sturgeon states that there is currently no specific treatment for Theiler’s disease. However, supportive care, including fluid therapy, nutritional support, and medications to manage symptoms, can be provided.

Prevention and Future Research

  • Sturgeon concludes the paper by emphasizing the importance of preventative measures, such as regular vaccinations, good hygiene standards during medical procedures, and quarantine of infected horses, to reduce the incidence of Theiler’s disease.
  • The article concludes with a call for further research into the disease to enhance understanding and improve treatment options.

Cite This Article

APA
Sturgeon B. (2017). Theiler’s disease. Vet Rec, 180(1), 14-15. https://doi.org/10.1136/vr.j8

Publication

ISSN: 2042-7670
NlmUniqueID: 0031164
Country: England
Language: English
Volume: 180
Issue: 1
Pages: 14-15

Researcher Affiliations

Sturgeon, Ben
  • Greenside Veterinary Practice, Greenside Farm, St Boswells, Melrose TD6 0AJ.

MeSH Terms

  • Acute Disease
  • Animals
  • Disease Outbreaks / statistics & numerical data
  • Disease Outbreaks / veterinary
  • Hepatitis, Animal / epidemiology
  • Horse Diseases / epidemiology
  • Horses
  • Liver / pathology
  • Necrosis / epidemiology
  • Necrosis / veterinary
  • Sentinel Surveillance / veterinary

Citations

This article has been cited 4 times.
  1. Jager MC, Choi E, Tomlinson JE, Van de Walle G. Naturally acquired equine parvovirus-hepatitis is associated with a wide range of hepatic lesions in horses. Vet Pathol 2024 May;61(3):442-452.
    doi: 10.1177/03009858231214024pubmed: 38018088google scholar: lookup
  2. Lee SK, Park D, Lee I. Molecular Prevalence of Equine Parvovirus-Hepatitis in the Sera of Clinically Healthy Horses in South Korea. Vet Sci 2021 Nov 19;8(11).
    doi: 10.3390/vetsci8110282pubmed: 34822655google scholar: lookup
  3. Meister TL, Tegtmeyer B, Brüggemann Y, Sieme H, Feige K, Todt D, Stang A, Cavalleri JV, Steinmann E. Characterization of Equine Parvovirus in Thoroughbred Breeding Horses from Germany. Viruses 2019 Oct 18;11(10).
    doi: 10.3390/v11100965pubmed: 31635426google scholar: lookup
  4. Chen F, Knutson TP, Braun E, Jiang Y, Rossow S, Marthaler DG. Semi-quantitative duplex RT-PCR reveals the low occurrence of Porcine Pegivirus and Atypical Porcine Pestivirus in diagnostic samples from the United States. Transbound Emerg Dis 2019 May;66(3):1420-1425.
    doi: 10.1111/tbed.13154pubmed: 30806022google scholar: lookup