Toward the incrimination of epidemic vectors of eastern equine encephalomyelitis virus in Massachusetts: abundance of mosquito populations at epidemic foci.
- Journal Article
- Research Support
- Non-U.S. Gov't
- Research Support
- U.S. Gov't
- Non-P.H.S.
Summary
The research investigates the mosquito populations carrying the Eastern equine encephalomyelitis virus (EEE) in Massachusetts, indicating that Coquillettidia perturbans, Aedes canadensis, and Culex salinarius mosquito species are more likely to spread EEE compared to Aedes vexans, Anopheles punctipennis, and Anopheles quadrimaculatus.
Objective and Methodology
- The research’s primary aim was to identify the key vectors, or transmitters, of the Eastern equine encephalomyelitis virus in southeastern Massachusetts, specifically in Bristol and Plymouth counties.
- 15 sites, where recent cases of EEE had been reported between 1982 and 1990 among horses and humans, were analyzed.
- Adult mosquitoes were trapped using light traps baited with carbon dioxide, a method used to estimate the biting risk in these areas known for transmission. This method imitates the presence of a potential host to attract mosquitoes.
- The research data indicated a high abundance of three specific mosquito species: Coquillettidia perturbans, Aedes canadensis, and Culex salinarius.
- This suggests that these species are more likely vectors or carriers of the EEE virus in Massachusetts.
- By contrast, other species such as Aedes vexans, Anopheles punctipennis, and Anopheles quadrimaculatus were found to be less likely responsible for the virus’s spread.
- This study is significant for public health as it helps pinpoint the mosquito species that should be the primary targets of eradication and control efforts in Massachusetts to curtail the spread of the EEE virus.
Findings and Conclusion
Without an understanding of the actual vectors of the disease, efforts to control the spread of this virus could be misdirected, potentially leading to wasted resources and ineffective disease control measures. Therefore, the researchers’ findings can help guide targeted interventions and disease control measures toward specific mosquito populations most likely causing EEE virus outbreaks.
Cite This Article
Publication
Researcher Affiliations
- Department of Entomology, University of Massachusetts, Amherst 01003, USA.
MeSH Terms
- Animals
- Culicidae
- Disease Outbreaks / veterinary
- Encephalitis Virus, Eastern Equine / pathogenicity
- Encephalomyelitis, Equine / transmission
- Horses
- Humans
- Insect Vectors
- Massachusetts / epidemiology
- Population Dynamics
Citations
This article has been cited 7 times.- Armstrong PM, Andreadis TG. Ecology and Epidemiology of Eastern Equine Encephalitis Virus in the Northeastern United States: An Historical Perspective. J Med Entomol 2022 Jan 12;59(1):1-13.
- Hughes HR, Velez JO, Davis EH, Laven J, Gould CV, Panella AJ, Lambert AJ, Staples JE, Brault AC. Fatal Human Infection with Evidence of Intrahost Variation of Eastern Equine Encephalitis Virus, Alabama, USA, 2019. Emerg Infect Dis 2021 Jul;27(7):1886-1892.
- Sherwood JA, Stehman SV, Howard JJ, Oliver J. Cases of Eastern equine encephalitis in humans associated with Aedes canadensis, Coquillettidia perturbans and Culiseta melanura mosquitoes with the virus in New York State from 1971 to 2012 by analysis of aggregated published data. Epidemiol Infect 2020 Apr 1;148:e72.
- Oliver J, Lukacik G, Kokas J, Campbell SR, Kramer LD, Sherwood JA, Howard JJ. Twenty years of surveillance for Eastern equine encephalitis virus in mosquitoes in New York State from 1993 to 2012. Parasit Vectors 2018 Jun 25;11(1):362.
- Shepard JJ, Andreadis TG, Thomas MC, Molaei G. Host associations of mosquitoes at eastern equine encephalitis virus foci in Connecticut, USA. Parasit Vectors 2016 Aug 30;9(1):474.
- Molaei G, Armstrong PM, Graham AC, Kramer LD, Andreadis TG. Insights into the recent emergence and expansion of eastern equine encephalitis virus in a new focus in the Northern New England USA. Parasit Vectors 2015 Oct 9;8:516.
- Weaver SC, Winegar R, Manger ID, Forrester NL. Alphaviruses: population genetics and determinants of emergence. Antiviral Res 2012 Jun;94(3):242-57.