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Home / Equine Research Bank / J Vet Sci / Training-induced changes in clotting parameters of athletic ...
Journal of veterinary science2013; 15(1); 45-49; doi: 10.4142/jvs.2014.15.1.45

Training-induced changes in clotting parameters of athletic horses.

Abstract: The purpose of this study was to investigate the effects of training on prothrombin time, activated partial thromboplastin time, and fibrinogen (Fb) concentrations in horses to assess potential adaptive response to training. Fifteen clinically healthy horses were enrolled in the present study and equally divided into three groups. Group A completed an intense training program, group B participated in a light training program, and group C included sedentary horses. After 5 weeks, group B was subjected to the same training program completed by group A and renamed group B1. Blood samples were collected by jugular venipuncture from each animal at rest and analyzed within 2 h after sampling. A two-way ANOVA for repeated measures showed a significant effect of training (p < 0.05) on Fb concentrations in group B1 alone during the first week after changing the training program. Our findings demonstrated that Fb is a parameter susceptible to training. Fb plasma levels increase with a more intense training program. However, Fb plasma levels decreased after the first week and returned to basel levels, suggesting that the horses had adapted to the new training program.
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Publication Date: 2013-10-18 PubMed ID: 24136203PubMed Central: PMC3973765DOI: 10.4142/jvs.2014.15.1.45Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research investigates how training impacts certain blood clotting parameters in athletic horses. The findings show that certain components of blood clotting are susceptible to training, with more intense training programs causing initial increases, followed by a decrease as the horses’ bodies adapt.

Research Objective

  • The aim of this study was to gauge the effects of different intensities of training on the blood clotting parameters of prothrombin time, activated partial thromboplastin time, and fibrinogen levels in horses. The study was designed to assess the potential adaptive response of these parameters to training alterations.

Methodology

  • Five horses were evenly assigned to three groups – Group A (intense training), Group B (light training), and Group C (sedentary or no training).
  • Group B, after five weeks, was subjected to the same intense training as Group A and renamed Group B1.
  • Blood samples were taken from the jugular vein of each horse at rest and analyzed within two hours of sampling.
  • Two-way ANOVA statistical analysis was used to determine any significant effect of the training on these blood clotting parameters.

Results

  • A significant effect of training on fibrinogen levels was observed in Group B1 in the first week after the training program was switched from light to intense. This indicates that fibrinogen levels are sensitive to alterations in training intensity.
  • The levels of fibrinogen in the plasma increased with the introduction of a more intense training program.
  • However, these increased fibrinogen levels decreased after the first week and returned back to baseline levels. This trend suggests that the horses’ bodies adapted to the new training program over time.

Conclusions

  • The study revealed that fibrinogen, a key component involved in blood clotting, responds notably to changes in training intensity. It highlighted that an intense training program initially elevates fibrinogen levels, which then decrease and normalize as the horse adapts to its new training routine.

Cite This Article

APA
Piccione G, Bazzano M, Giannetto C, Marafioti S, Fazio F. (2013). Training-induced changes in clotting parameters of athletic horses. J Vet Sci, 15(1), 45-49. https://doi.org/10.4142/jvs.2014.15.1.45

Publication

Journal of veterinary science
ISSN: 1976-555X
NlmUniqueID: 100964185
Country: Korea (South)
Language: English
Volume: 15
Issue: 1
Pages: 45-49

Researcher Affiliations

Piccione, Giuseppe
  • Department of Veterinary Science, University of Messina, Polo Universitario dell'Annunziata, 98168 Messina, Italy.guiseppe.piccione@unime.it.
Bazzano, Marilena
    Giannetto, Claudia
      Marafioti, Simona
        Fazio, Francesco

          MeSH Terms

          • Animals
          • Female
          • Fibrinogen / metabolism
          • Horses / physiology
          • Male
          • Partial Thromboplastin Time / veterinary
          • Physical Conditioning, Animal
          • Prothrombin Time / veterinary

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          Citations

          This article has been cited 5 times.
          1. Miglio A, Falcinelli E, Mezzasoma AM, Cappelli K, Mecocci S, Gresele P, Antognoni MT. Effect of First Long-Term Training on Whole Blood Count and Blood Clotting Parameters in Thoroughbreds. Animals (Basel) 2021 Feb 9;11(2).
            doi: 10.3390/ani11020447pubmed: 33572086google scholar: lookup
          2. Piccione G, Arfuso F, Giudice E, Aragona F, Pugliatti P, Panzera MF, Zumbo A, Monteverde V, Bartolo V, Barbera A, Giannetto C. Dynamic Adaptation of Hematological Parameters, Albumin, and Non-Esterified Fatty Acids in Saddlebred and Standardbred Horses During Exercise. Animals (Basel) 2025 Jan 21;15(3).
            doi: 10.3390/ani15030300pubmed: 39943070google scholar: lookup
          3. Miglio A, Falcinelli E, Mezzasoma AM, Busechian S, Rueca F, Gresele P, Antognoni MT. Biomarkers of in vivo platelet activation in thoroughbreds during their first long-term training. Front Vet Sci 2024;11:1395423.
            doi: 10.3389/fvets.2024.1395423pubmed: 38831955google scholar: lookup
          4. Tkaczenko H, Lukash O, Kurhaluk N. Analysis of the season-dependent component in the evaluation of morphological and biochemical blood parameters in Shetland ponies of both sexes during exercise. J Vet Res 2024 Mar;68(1):155-166.
            doi: 10.2478/jvetres-2024-0017pubmed: 38525221google scholar: lookup
          5. Miglio A, Falcinelli E, Cappelli K, Mecocci S, Mezzasoma AM, Antognoni MT, Gresele P. Effect of Regular Training on Platelet Function in Untrained Thoroughbreds. Animals (Basel) 2024 Jan 27;14(3).
            doi: 10.3390/ani14030414pubmed: 38338057google scholar: lookup
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