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Home / Equine Research Bank / J Vet Intern Med / Transvenous electrical cardioversion of atrial fibrillation ...
Journal of veterinary internal medicine2022; 36(2); 758-769; doi: 10.1111/jvim.16395

Transvenous electrical cardioversion of atrial fibrillation in horses: Horse and procedural factors correlated with success and recurrence.

Abstract: Transvenous electrical cardioversion (TVEC) is 1 of the main treatment options for atrial fibrillation (AF) in horses. Large-scale studies on factors affecting success and prognosis have primarily been performed in Standardbred populations. Objective: To determine factors affecting cardioversion success, cardioversion difficulty and recurrence in a predominant Warmblood study sample. Methods: TVEC records of 199 horses. Methods: Retrospective study of TVEC procedures of horses admitted for AF without severe echocardiographic abnormalities. Horse and procedural factors for success and cumulative amount of energy (≤ 600 J vs > 600 J) were determined using multivariable logistic regression. A survival analysis was performed to determine risk factors for recurrence. Results: Two hundred and thirty-one TVEC procedures were included, with a 94.4% success rate and 31.9% recurrence rate (51/160). Mitral regurgitation (OR 0.151, 95% CI 0.032-0.715, P = .02) and AF cycle length (OR 1.05, 95% CI 1.01-1.09, P = .02) were independent determinants for success. Catheter type (OR 0.154, 95% CI 0.074-0.322, P < .001), previous AF episode (OR 3.10, 95% CI 1.20-8.01, P = .02), tricuspid regurgitation (OR 2.54, 95% CI 1.25-5.13, P = .01), and body weight (OR 1.009, 95% CI 1.003-1.015, P = .004) were significantly correlated with cumulative amount of energy delivered. Significant risk factors for recurrence after a first AF episode were sex (stallion; HR 3.05, 95% CI 1.34-6.95, P = .008), mitral regurgitation (HR 1.91, 95% CI 1.08-3.38, P = .03), and AF duration (HR 1.001, 95% CI 1.0001-1.0026, P = .04). Conclusions: Both horse and procedural factors should be considered when assessing treatment options and prognosis in horses with AF.
© 2022 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine.
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Publication Date: 2022-03-05 PubMed ID: 35246994PubMed Central: PMC8965264DOI: 10.1111/jvim.16395Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article is about a study conducted to identify factors that impact the success and recurrence rate of transvenous electrical cardioversion (TVEC), a main treatment option for atrial fibrillation (AF) in horses. The study specifically focused on a major Warmblood study sample.

Introduction

The study conducted researched the successful results of transvenous electrical cardioversion (TVEC), one of the primary treatments for atrial fibrillation (AF) in horses. It took into account a predominantly Warmblood sample size and aimed to determine the factors affecting the success and frequency of recurrence post-procedure.

Methodology

  • The study used a sample size of 199 horses and analyzed retrospective data of TVEC procedures.
  • These horses were suffering from AF but did not show severe echocardiographic abnormalities.
  • To identify influencing factors, multivariable logistic regression was utilized considering both the horse’s characteristics and procedure details.
  • The amount of energy used during these procedures was also a major factor considered and two categories were established for analysis: energy less than or equal to 600 J, and energy greater than 600 J.

Results

  • The success rate was notably high, standing at 94.4% out of 231 examined TVEC procedures.
  • The recurrence rate of AF was found to be 31.9% (51 out of 160 cases).
  • In terms of factors influencing success, independent determinants were found to be the presence of mitral regurgitation and the AF cycle length.
  • Determinants correlating with the cumulative amount of energy delivered were catheter type, previous AF episodes, tricuspid regurgitation, and the body weight of the horse.
  • Risk factors for recurrence post-AF episode were identified as sex of the horse (stallions had higher recurrence), mitral regurgitation, and the duration of AF.

Conclusions

In conclusion, the study reinforced the importance of considering both horse-specific and procedural factors when forecasting treatment options and prognosis for horses suffering from AF. Evidently, with certain factors, TVEC procedures had high success rates but risk of recurrence requires further exploration.

Cite This Article

APA
Vernemmen I, Van Steenkiste G, Dufourni A, Decloedt A, van Loon G. (2022). Transvenous electrical cardioversion of atrial fibrillation in horses: Horse and procedural factors correlated with success and recurrence. J Vet Intern Med, 36(2), 758-769. https://doi.org/10.1111/jvim.16395

Publication

Journal of veterinary internal medicine
ISSN: 1939-1676
NlmUniqueID: 8708660
Country: United States
Language: English
Volume: 36
Issue: 2
Pages: 758-769

Researcher Affiliations

Vernemmen, Ingrid
  • Equine Cardioteam, Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Van Steenkiste, Glenn
  • Equine Cardioteam, Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Dufourni, Alexander
  • Equine Cardioteam, Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Decloedt, Annelies
  • Equine Cardioteam, Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
van Loon, Gunther
  • Equine Cardioteam, Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.

MeSH Terms

  • Animals
  • Atrial Fibrillation / therapy
  • Atrial Fibrillation / veterinary
  • Echocardiography / veterinary
  • Electric Countershock / veterinary
  • Horse Diseases / etiology
  • Horse Diseases / therapy
  • Horses
  • Male
  • Recurrence
  • Retrospective Studies

Grant Funding

  • 1S56217N / Fonds Wetenschappelijk Onderzoek

Conflict of Interest Statement

Authors declare no conflict of interest.

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Citations

This article has been cited 3 times.
  1. Natterson-Horowitz B, Wright K, Van Steenkiste G, Decloedt A, Gagnon AL, Cai X, Mazmanian A. Arrhythmias across the tree of life: comparative insights for human electrophysiology. Front Cardiovasc Med 2025;12:1652591.
    doi: 10.3389/fcvm.2025.1652591pubmed: 41567384google scholar: lookup
  2. Nath LC, Elliott A, La Gerche A, Weir J, Forbes G, Thomas G, Franklin S. Associations between postrace atrial fibrillation and measures of performance, racing history and airway disease in horses. J Vet Intern Med 2023 Nov-Dec;37(6):2573-2583.
    doi: 10.1111/jvim.16878pubmed: 37740606google scholar: lookup
  3. Van Steenkiste G, Boussy T, Duytschaever M, Vernemmen I, Schauvlieghe S, Decloedt A, van Loon G. Detection of the origin of atrial tachycardia by 3D electro-anatomical mapping and treatment by radiofrequency catheter ablation in horses. J Vet Intern Med 2022 Jul;36(4):1481-1490.
    doi: 10.1111/jvim.16473pubmed: 35686355google scholar: lookup
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