Treatment of an ocular squamous cell carcinoma in a stallion with atrial fibrillation.
Abstract: A stallion was presented for surgical treatment of limbal squamous cell carcinoma. Excision with a conjunctival pedicle flap was done to prevent ocular invasion and preserve vision. A complication was the diagnosis of atrial fibrillation, which was not converted to sinus rhythm due to the potential complication of treatment with quinidine sulfate. Traitement d’un carcinome épidermoïde oculaire chez un étalon atteint de fibrillation auriculaire. Un étalon a été présenté pour une chirurgie d’un carcinome épidermoïde limbique. Après l’excision, un lambeau à pédicule conjonctival a été réalisé pour prévenir l’invasion oculaire et préserver la vue. Un diagnostic de fibrillation auriculaire est venu compliquer le cas : il n’y a pas eu de conversion en rythme sinusal à cause d’une possibilité de complication avec le traitement au sulfate de quinidine. (Traduit par Docteur André Blouin)
Publication Date: 2006-02-04 PubMed ID: 16454385PubMed Central: PMC1255595
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Summary
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This research paper discusses the surgical treatment of an eye cancer, specifically limbal squamous cell carcinoma, in a stallion (male horse) concurrently suffering from atrial fibrillation, a heart disorder. The heart disorder complicated treatment because the medicine typically used could potentially introduce other complications.
About the Case
- The study is based on a case of a stallion that was diagnosed with an ocular disorder, known as limbal squamous cell carcinoma.
- This is a form of cancer that affects the eye. Specifically, it develops in the limbus, which is the border area between the clear cornea at the front of the eye and the white sclera – the outer layer of the eye.
Surgical Treatment
- The stallion was presented for surgical treatment of this cancer. The chosen method of treatment was to excise the cancerous tissues.
- In order to prevent the cancer from spreading into the eye and to preserve the animal’s vision, a surgical technique called a conjunctival pedicle flap was performed after the excision.
- This technique involves creating a flap of healthy tissue from the conjunctiva – the clear tissue covering the white part of the eye, and using it to repair the area where the cancer has been removed.
Complication of the Case
- A complication of this case was that the stallion was also diagnosed with a heart disorder called atrial fibrillation. This is a condition characterized by irregular, often rapid heart rate that can lead to poor blood flow to the body.
- Under normal circumstances, atrial fibrillation can be treated and converted back to normal heart rhythm (sinus rhythm) using a medication called quinidine sulfate.
- However, in this case, the treatment could not be given due to the potential for it to cause complications in combination with the surgical treatment for the eye cancer.
Conclusion
- This case highlights the potential challenges of treating ocular squamous cell carcinoma in horses that have other underlying health conditions. In this scenario, the presence of atrial fibrillation complicated the treatment protocol, dictating a more cautious approach in managing the patient’s health.
Cite This Article
APA
Scheck JL.
(2006).
Treatment of an ocular squamous cell carcinoma in a stallion with atrial fibrillation.
Can Vet J, 46(10), 922-924.
Publication
Researcher Affiliations
- Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B7. jls250@mail.usask.ca
MeSH Terms
- Animals
- Atrial Fibrillation / complications
- Atrial Fibrillation / veterinary
- Carcinoma, Squamous Cell / surgery
- Carcinoma, Squamous Cell / veterinary
- Corneal Surgery, Laser / methods
- Corneal Surgery, Laser / veterinary
- Eye Neoplasms / surgery
- Eye Neoplasms / veterinary
- Horse Diseases / surgery
- Horses
- Male
- Neoplasm Recurrence, Local / veterinary
- Treatment Outcome
References
This article includes 9 references
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- Joyce JR. Cryosurgical treatment of tumors in horses and cattle. J Am Vet Med Assoc 1976;168:226–229.
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- McCalla TL, Moore CP, Collier LL. Immunotherapy of periocular squamous cell carcinoma with metastasis in a pony. J Am Vet Med Assoc 1992;200:1678–1680.
- English RV, Naisse MP, Davidson MG. Carbon dioxide laser ablation for treatment of limbal squamous cell carcinoma in horses. J Am Vet Med Assoc 1990;196:439–442.
- Reef VB, Levitan CW. Factors Affecting prognosis and conversion in equine atrial fibrillation. J Vet Int Med 1988;2:1–6.
- Taylor PM, Clarke KW. Handbook of Equine Anesthesia. London: WB Saunders, 1999:105–106.
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