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Case reports in veterinary medicine2025; 2025; 4021047; doi: 10.1155/crve/4021047

Treatment of Iris Hypoplasia Using Semiconductor Diode Laser in the Horse Under Standing Sedation.

Abstract: This study is aimed at describing two unique case presentations of iris hypoplasia and the use of semiconductor diode laser for treatment in the horse. One 20-year-old American Quarter Horse gelding and one 11-year-old pony mare were studied. The presenting clinical signs, surgical technique, and postoperative results for two cases of iris hypoplasia treated with diode laser are described. Immediate postoperative complications-postoperative ocular hypertension (POH), corneal edema, and epithelial bullae-were possible anticipated effects but were controlled with topical medications in the first case. Following treatment, endothelial contact of the iris was eliminated, and a functional pupil was established in the first case. Anterior synechia occurred long-term but did not lead to pupil obstruction. Left untreated, the iris hypoplasia in the right eye progressed to a degree like that seen upon initial presentation in the left eye. In the second case, the area of the distended, hypoplastic iris was reduced, and the pupil remained functional. Diode laser ablation of hypoplastic iridal tissue was effective at eliminating anterior synechia in both cases presented here. The better functional results in Case 2 suggest that early intervention may result in more favorable outcomes.
Publication Date: 2025-03-24 PubMed ID: 40166363PubMed Central: PMC11957872DOI: 10.1155/crve/4021047Google Scholar: Lookup
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Summary

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This research article studies the treatment of a condition called Iris Hypoplasia in horses using a method involving a semiconductor diode laser. Two unique case studies are presented to demonstrate its effectiveness with the key findings highlighting that early intervention may produce better results.

Objective and Methodology

  • The study focuses on investigating two distinct cases of iris hypoplasia—a condition where the iris of the eye is underdeveloped—in horses and how semiconductor diode laser treatment can aid in alleviating the symptoms.
  • The subjects of the study were a 20-year-old American Quarter Horse gelding and an 11-year-old pony mare.
  • The researchers describe the clinical symptoms that were observed, the surgical procedure employing the semiconductor diode laser, and the postoperative results.

Results and Observations

  • In the first case, immediate postoperative complications were anticipated, including ocular hypertension (increased pressure in the eye), corneal edema (swelling of the cornea), and epithelial bullae (fluid-filled blisters on the eye’s surface).
  • However, these complications were managed with the use of topical medications.
  • The diagnosis post-treatment revealed that the iris no longer had direct contact with the endothelium (the interior layer of the eye), and a functional and responsive pupil was established.
  • In the long term, anterior synechia (attachment between the iris and cornea) was observed, but this did not obstruct the pupil.
  • In the untreated eye, the condition of iris hypoplasia advanced to a degree similar to the initial state of the treated eye.
  • In the second case, post-treatment observations revealed a reduction in the distended (swollen or extended) and underdeveloped area of the iris and a functional pupil was maintained.

Conclusions

  • The semiconductor diode laser treatment was found to be successful in eliminating anterior synechia in both the cases.
  • The results of the second case indicate that early intervention can potentially provide more favorable results, implying the importance of timely diagnosis and treatment.

Cite This Article

APA
Hefner EM, Stoppini R, McMullen RJ. (2025). Treatment of Iris Hypoplasia Using Semiconductor Diode Laser in the Horse Under Standing Sedation. Case Rep Vet Med, 2025, 4021047. https://doi.org/10.1155/crve/4021047

Publication

ISSN: 2090-701X
NlmUniqueID: 101586276
Country: United States
Language: English
Volume: 2025
Pages: 4021047
PII: 4021047

Researcher Affiliations

Hefner, Ethan M
  • JT Vaughan Large Animal Teaching Hospital, College of Veterinary Medicine, Auburn University College of Veterinary Medicine, Auburn, Alabama, USA.
  • Animal Eye Care of the Lowcountry, Ladson, South Carolina, USA.
Stoppini, Riccardo
  • Equine Ophthalmology Consultant, Cascina Gufa Equine Clinic, Merlino, Lodi, Italy.
McMullen, Richard J
  • JT Vaughan Large Animal Teaching Hospital, College of Veterinary Medicine, Auburn University College of Veterinary Medicine, Auburn, Alabama, USA.
  • Equine Department, University of Zurich, Zurich, Switzerland.

Conflict of Interest Statement

The authors declare no conflicts of interest.

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Citations

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