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Equine veterinary journal1979; 11(1); 3-10; doi: 10.1111/j.2042-3306.1979.tb01283.x

Treatment of periocular tumours of horses using radioactive gold198 grains.

Abstract: The literature is briefly reviewed concerning the clinical features of equine cutaneous tumours. The data from 19 horses with periocular skin tumours are reported together with the results of their treatment by implantation with radioactive gold198. The principles governing the implantation of radioactive sources are explained and a method for computing the initial activity of the sources is outlined. Five histologically different tumour types were treated in this series of 19 horses, 2 horses were bilaterally affected. The techniques of implantation using a simple needle/stillette combination and a purpose built gold grain implantation gun are described and the postoperative course of the animals is traced. The treatment was successful in ablating the tumour mass and preventing regrowth in 19 of 21 periocular tumour groups. The cosmetic effects of the treatment were found to be satisfactory. Emphasis is laid on the care needed in handling the radioactive material and on the need for a thorough understanding of the principles involved in radiotherapy. Doses received by the operator during an implantation procedure are quoted which show that the technique is safe as well as being effective.
Publication Date: 1979-01-01 PubMed ID: 428361DOI: 10.1111/j.2042-3306.1979.tb01283.xGoogle Scholar: Lookup
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  • Journal Article

Summary

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This research article reports on the treatment of periocular tumours in horses through the implantation of radioactive gold198, providing an overview of the procedure and demonstrating its effectiveness and safety.

Review of Equine Cutaneous Tumours

  • The paper begins with a brief review of previous literature on the clinical features of equine cutaneous tumours.
  • It provides necessary background knowledge and sets the context for the rest of the study.

Data Collection and Analysis

  • The researchers gathered data from 19 horses suffering from periocular skin tumours.
  • The results of the treatment of these tumours with radioactive gold198 are discussed in detail.
  • In addition, the principles governing the implantation of radioactive sources are explained, along with a method for calculating the initial activity of the sources.

Implantation Techniques

  • The article elaborates on the different techniques used for the implantation process, which involves a simple needle/stillette combination or a specially designed gold grain implantation gun.
  • They have also chronicled the postoperative progress of the animals, providing valuable insight into the recovery process.
  • From the 19 horses treated, five different tumour types were identified, with two horses having tumours on both sides.

Results of the Treatment

  • The results of the study were overwhelmingly positive, with successful ablation of the tumour mass and prevention of regrowth in 19 out of 21 periocular tumour groups.
  • The treatment also had satisfactory cosmetic effects, which may be an important consideration in many cases, especially for show animals.

Safety Precautions and Dose Assessment

  • The authors emphasize the need for safe handling of radioactive materials and a thorough understanding of radiotherapy principles, advocating for caution and education in the application of this treatment.
  • They also provide figures for the doses received by the operator during an implantation procedure, reinforcing the safety as well as effectiveness of the technique.

Cite This Article

APA
Wyn-Jones G. (1979). Treatment of periocular tumours of horses using radioactive gold198 grains. Equine Vet J, 11(1), 3-10. https://doi.org/10.1111/j.2042-3306.1979.tb01283.x

Publication

ISSN: 0425-1644
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 11
Issue: 1
Pages: 3-10

Researcher Affiliations

Wyn-Jones, G

    MeSH Terms

    • Animals
    • Carcinoma, Squamous Cell / radiotherapy
    • Carcinoma, Squamous Cell / veterinary
    • Eyelid Neoplasms / radiotherapy
    • Eyelid Neoplasms / veterinary
    • Female
    • Fibroma / radiotherapy
    • Fibroma / veterinary
    • Gold Radioisotopes / administration & dosage
    • Horse Diseases / radiotherapy
    • Horses
    • Male
    • Neoplasm Recurrence, Local

    Citations

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