Treatment with a High Dose Combination of PMSG/hCG Preparation of Mares Clinically Diagnosed with Ovarian Quiescence during the Breeding Season (Investigation from 1975 to 2000).
Abstract: A total of 88 thoroughbred mares were diagnosed with clinical ovarian quiescence and subjected to four treatment regimens. Using PMSG, hCG or combinations of both. A high dose combination of 5,000IU PMSG with 5,000IU hCG showed significantly higher rates of marked estrus and ovulation induction (P<0.01) as well as conception rates (P<0.05). In the present study, the administration of a high-dose combination of PMSG with hCG was shown to be an effective treatment of ovarian quiescence in light mares.
Publication Date: 2008-07-09 PubMed ID: 24833954PubMed Central: PMC4013944DOI: 10.1294/jes.19.35Google Scholar: Lookup
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Summary
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The study indicates that using a high dose combination of PMSG and hCG hormones effectively treats ovarian quiescence in thoroughbred mares, improving estrus, ovulation, and conception rates significantly.
Understanding Ovarian Quiescence
- Ovarian quiescence refers to a state of inactivity or rest of the ovaries where they don’t release eggs regularly. This condition can hinder the breeding process in mares as the regular release of eggs, a process known as ovulation, is necessary for conception.
The Scope of the Study
- The study spanned from 1975 to 2000, consisting of 88 thoroughbred mares diagnosed with clinical ovarian quiescence.
- The researchers subjected these mares to four different treatment regimens. These treatments comprised varying combinations of two hormones – PMSG (Pregnant Mare’s Serum Gonadotropin) and hCG (Human Chorionic Gonadotropin).
- The purpose of these treatments was to investigate the most effective method to treat ovarian quiescence, stimulate estrus (the period of sexual receptivity), induce ovulation, and increase conception rates.
Efficacy of the PMSG/hCG Combination
- The most significant results were seen in the group of mares treated with a high-dose combination of PMSG and hCG. Specifically, this regimen consisted of 5,000 International Unit (IU) PMSG and 5,000 IU hCG.
- The mares treated with this regimen showed significantly higher rates of marked estrus, ovulation induction, and conception rates compared to the other groups.
Implications of the Study
- The results, therefore, support that a high-dose combination of PMSG and hCG is an effective treatment method for dealing with ovarian quiescence in light mares.
- This has valuable implications for the horse breeding industry since improving ovulation and conception rates of mares can result in increased efficiency, productivity, and success in breeding thoroughbreds.
Cite This Article
APA
Tsukada T, Sato K, Moriyoshi M, Koyago M, Sawamukai Y.
(2008).
Treatment with a High Dose Combination of PMSG/hCG Preparation of Mares Clinically Diagnosed with Ovarian Quiescence during the Breeding Season (Investigation from 1975 to 2000).
J Equine Sci, 19(2), 35-38.
https://doi.org/10.1294/jes.19.35 Publication
Researcher Affiliations
- Tsukada Livestock Clinic, Mitsuishi, Hokkaido 059-3231, Japan.
- Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan.
- Department of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan.
- Department of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan.
- Department of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan.
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