Turbidimetric measurement of IgG(T) in the serum of healthy Thoroughbreds and ponies.
- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
This research explores the method of measuring IgG(T) in the serum of horses using turbidimetric analysis and provides reference values for different types of horses in varying health conditions.
Understanding the Research
This study employed a test method known as turbidimetric analysis to examine the level of Immunoglobulin G(T), abbreviated as IgG(T), in the blood serum of various horses. List of key points to understand are as follows:
- Turbidimetric analysis is a technique where the amount of light transmitted through a solution is measured to determine the concentration of particles within it. In this case, it’s used to gauge the concentration of IgG(T) within horse serum.
- IgG(T) refers to a type of antibody (Immunoglobulin G type T) found in blood serum. It’s part of the horse’s immune system and is typically engaged when the animal is fighting an infection or disease.
- The animals involved in this study comprised of ‘worm-free’ ponies, two-year-old and older stabled Thoroughbreds, Thoroughbred broodmares in grazing conditions, and regularly wormed adult and young ponies in a pasture with intestinal parasite eggs and larvae.
Significant Findings
Upon conducting the analysis, the study derives sets of reference values for different types of horses under varying conditions.
- ‘Worm-free’ ponies had an IgG(T) concentration of 2.6 +/- 0.7 g/litre.
- Stabled Thoroughbreds two years old and over had a slightly higher concentration at 4.1 +/- 1.3 g/litre.
- Grazing Thoroughbred broodmares had noticeably higher levels at 7.1 +/- 2.4 g/litre.
- Finally, regularly wormed adult and young ponies in a parasite-contaminated grazing environment had varied concentrations.
The research indicates that the environmental conditions, age, health status, and breed of the horse potentially affect the IgG(T) concentration in their serum. This understanding can be useful in veterinary medicine, aiding in diagnosing infections or immune-related conditions in horses. The established reference values can be a benchmark to compare future test results against, thus improving the accuracy and reliability of diagnoses.
Cite This Article
Publication
Researcher Affiliations
MeSH Terms
- Animals
- Female
- Horses / immunology
- Immunoglobulin G / metabolism
- Male
- Nephelometry and Turbidimetry
- Strongyle Infections, Equine / immunology
Citations
This article has been cited 1 times.- Eckersall PD, Conner JG, Harvie J. An immunoturbidimetric assay for canine C-reactive protein. Vet Res Commun 1991;15(1):17-24.