Two different clinical forms of squamous cell carcinoma (SCC) in the perineum and vulva of two mares.
Abstract: Genital malignant neoplasms in mares are relatively rare. The treatment involve surgical removal of the tumour masses, chemotherapy or both. Methods: Two elderly warmblood mares, aged 16 and 20 were presented in University Clinic with the lumpy lesions at the region of perineum and left labia. Surgical removals of tumour masses were performed on standing animals. Removed tissues were subjected to histopathological examination which confirmed SCC. Conclusions: Clinical and ultrasound examination of reproductive organs in both mares showed no inflammatory or neoplastic changes. Both mares healed within 2 weeks after surgery and showed no signs of tumour recurrence for the following year despite no chemotherapy treatment.
Publication Date: 2020-11-30 PubMed ID: 33256709PubMed Central: PMC7708236DOI: 10.1186/s12917-020-02678-9Google Scholar: Lookup
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Summary
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The research article studies two instances of squamous cell carcinoma (SCC) in the genital region of two mares, highlighting successful treatment solely through surgery without the use of chemotherapy.
Objectives and Subjects of the Study
- The main objective of this study was to understand and explore the nature of squamous cell carcinoma (SCC) in the perineum and vulva of mares, which are generally rare occurrences.
- The study focused on two specific cases involving two aged warmblood mares, who were found to have lumpy lesions in the region of the perineum and left labia.
Methods
- The treatment protocol involved the surgical removal of the tumour masses, under local anesthesia, while the mares were standing.
- Post-surgical tissue samples were subjected to histopathological examination. This examination confirmed the presence of SCC in both mares.
Findings and Conclusions
- Subsequent clinical and ultrasound examination of the reproductive organs in both mares showed no signs of inflammation or neoplastic changes, indicating successful surgical intervention.
- Interestingly, both mares healed completely within two weeks after surgery, despite not undergoing any subsequent chemotherapy treatment.
- The study underlines the significance of careful clinical examination and consistent follow-up post-surgery, as no signs of tumour recurrence were found for a year following the surgical treatment.
- The cases strongly suggest surgery as a viable treatment option for such types of SCC in mares.
Cite This Article
APA
Raś A, Otrocka-Domagała I, Raś-Noryńska M.
(2020).
Two different clinical forms of squamous cell carcinoma (SCC) in the perineum and vulva of two mares.
BMC Vet Res, 16(1), 464.
https://doi.org/10.1186/s12917-020-02678-9 Publication
Researcher Affiliations
- Department of Animal Reproduction with Clinic, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, ul. Oczapowskiego 14, 10-781, Olsztyn, Poland. andrzej.ras@wp.pl.
- Department of Pathological Anatomy, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, ul. Oczapowskiego 13, 10-781, Olsztyn, Poland.
- Department of Parasitology and Invasive Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, ul. Oczapowskiego 13, 10-781, Olsztyn, Poland.
MeSH Terms
- Animals
- Carcinoma, Squamous Cell / surgery
- Carcinoma, Squamous Cell / veterinary
- Female
- Horse Diseases / pathology
- Horses
- Perineum / pathology
- Perineum / surgery
- Treatment Outcome
- Vulva / pathology
- Vulva / surgery
- Vulvar Neoplasms / surgery
- Vulvar Neoplasms / veterinary
Conflict of Interest Statement
The authors declare that they have no competing interests.
References
This article includes 8 references
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