[Two horses with neurological symptoms: could this be equine botulism?].
Abstract: Symptoms, diagnosis and therapy of equine botulism are discussed by the presentation of two detailed reports of horses with neurological symptoms and the results of laboratory investigations over the period 2003-2008 in the Netherlands. In addition a brief summary of the available literature is presented. Prevailing symptoms of botulism in horses include paralysis of the tongue, salvation, dysphagia and paresis and paralysis of the skeletal muscles, as well as signs of colic. Symptoms and prognosis vary with the amount of botulinum neurotoxin (BoNT) involved. For early clinical diagnosis of botulism thorough investigation of the facial nerves is important, for instance by the use of the 'Tongue Stress Test'. Laboratory results often remain negative, probably due to the sampling time, the high sensitivity of horses for botulinum neurotoxin or treatment with antitoxins. Most clinical cases in horses are caused by botulinum neurotoxin B (BoNT/B). For therapy to be successful antiserum needs to be administered in the earliest possible stage of the disease and this should be supported by symptomatic therapy. Botulism is a feed-related intoxication caused by either carcasses in the roughage or BoNT/B production after poor conservation of grass silage. This is the main source of botulism in horses due to the popularity of individually packed grass silage as feed for horses. As long as no vaccine is available in the Netherlands quality control of silage and haylage is strictly recommended in order to reduce the risk of botulism in horses.
Publication Date: 2009-11-07 PubMed ID: 19891336
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Summary
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This research article discusses the symptoms, diagnosis, and treatment of botulism in horses, illustrated through case studies from the Netherlands between 2003 and 2008, and proposes silage quality control as a preventive measure given the absence of a vaccine.
Overview of Equine Botulism
- Equine botulism is a feed-related intoxication in horses primarily caused by the ingestion of botulinum neurotoxin B (BoNT/B), often produced following inadequate preservation of grass silage.
- While signs of botulism vary depending on the amount of BoNT ingested, common symptoms include tongue paralysis, salvation, difficulty in swallowing (dysphagia), partial (paresis) or complete paralysis of the skeletal muscles, and signs of colic.
Diagnosis and Treatment of Botulism in Horses
- The diagnosis of botulism relies heavily on clinical signs. However, a thorough investigation of the facial nerves, such as through the ‘Tongue Stress Test’, can aid in early diagnosis.
- One of the challenges in diagnosing botulism in horses is that laboratory results often remain negative. This could be attributed to the timing of the sample collection, the high sensitivity of horses to BoNT, or antitoxin treatment.
- Botulism treatment in horses involves the earliest possible administration of antiserum, complemented by symptomatic therapy.
Prevention of Botulism in Horses
- Since the main source of botulism in horses is the ingestion of poorly preserved grass silage, ensuring the grass silage quality control can significantly reduce the risk of the disease.
- In the absence of a botulism vaccine in the Netherlands, the researchers emphasize the importance of strict quality control of silage and haylage to minimize the risk of botulism in horses.
Cite This Article
APA
Roest HI, de Bruijn CM, Picavet MT, Prins B, Parmentier D, de Zwart GM, Dijkstra YE, van Zijderveld FG.
(2009).
[Two horses with neurological symptoms: could this be equine botulism?].
Tijdschr Diergeneeskd, 134(19), 790-795.
Publication
Researcher Affiliations
- Divisie Bacteriologie en TSE'S, Centraal Veterinair Instituut van Wageningen UR, Lelystad, Nederland. hendrikjan.roest@wur.nl
MeSH Terms
- Animals
- Antitoxins / therapeutic use
- Botulism / diagnosis
- Botulism / drug therapy
- Botulism / veterinary
- Clostridium botulinum type B / isolation & purification
- Fatal Outcome
- Female
- Food Contamination
- Horse Diseases / diagnosis
- Horse Diseases / drug therapy
- Horses
- Male
References
This article includes 26 references
Citations
This article has been cited 1 times.- Lang HM, Panizzi L, Smyth TT, Plaxton AE, Lohmann KL, Barber SM. Management and long-term outcome of partial glossectomy in 2 horses. Can Vet J 2014 Mar;55(3):263-7.
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