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The Veterinary clinics of North America. Equine practice2013; 29(3); 541-550; doi: 10.1016/j.cveq.2013.08.005

Update on equine allergies.

Abstract: Horses develop many skin and respiratory disorders that have been attributed to allergy. These disorders include pruritic skin diseases, recurrent urticaria, allergic rhinoconjunctivitis, and reactive airway disease. Allergen-specific IgE has been detected in these horses, and allergen-specific immunotherapy is used to ameliorate clinical signs. The best understood atopic disease in horses is insect hypersensitivity, but the goal of effective treatment with allergen-specific immunotherapy remains elusive. In this review, updates in pathogenesis of allergic states and a brief mention of the new data on what is known in humans and dogs and how that relates to equine allergic disorders are discussed.
Publication Date: 2013-10-25 PubMed ID: 24267673DOI: 10.1016/j.cveq.2013.08.005Google Scholar: Lookup
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  • Journal Article

Summary

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This research article provides an updated overview on equine allergies, discussing their types, causes, and potential treatments, with a particular focus on insect hypersensitivity. It also covers new findings concerning allergy pathogenesis and how human and dog allergies might relate to those found in horses.

Allergy Types in Horses

  • The article explores various types of disorders in horses that are associated with allergy. These include pruritic skin diseases (itchy skin disorders), recurrent urticaria (frequent hives), allergic rhinoconjunctivitis (allergy-related inflammation of the conjunctiva and nasal mucosa), and reactive airway disease (a group of conditions that narrows the tubes in the lungs).

Allergen-specific IgE and Immunotherapy

  • The study confirms the presence of allergen-specific IgE antibodies (antibodies that react specifically to certain allergens, facilitating an allergic reaction) in these horses.
  • Allergen-specific immunotherapy (a treatment for allergies that involves introducing the body to small amounts of the allergen to develop immunity) is used to reduce clinical signs of the allergic reaction.

Insect Hypersensitivity

  • The article takes special attention to insect hypersensitivity, which is the most understood atopic disease in horses. Atopy is the genetic tendency to develop allergic diseases. However, finding an effective treatment for this specific allergy with allergen-specific immunotherapy remains a challenge.

Updates on Allergy Pathogenesis and Relation to Human and Dog Allergies

  • The article provides a brief overview of new information regarding the development and progression of allergies.
  • It also draws a comparison between equine allergies and those found in humans and dogs, suggesting potential similarities that may aid in further understanding and managing the allergic reactions in horses.

Cite This Article

APA
Fadok VA. (2013). Update on equine allergies. Vet Clin North Am Equine Pract, 29(3), 541-550. https://doi.org/10.1016/j.cveq.2013.08.005

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 29
Issue: 3
Pages: 541-550

Researcher Affiliations

Fadok, Valerie A
  • Dermatology Department, North Houston Veterinary Specialists, 1646 Spring Cypress Road #100, Spring, TX 77388, USA. Electronic address: vfadokdvm@nhvetspecialists.com.

MeSH Terms

  • Animals
  • Horse Diseases / diagnosis
  • Horse Diseases / immunology
  • Horse Diseases / therapy
  • Horses
  • Humans
  • Hypersensitivity / diagnosis
  • Hypersensitivity / immunology
  • Hypersensitivity / therapy
  • Hypersensitivity / veterinary

Citations

This article has been cited 9 times.
  1. Pessoa VC, Branco-Ferreira M, Jónsdóttir S, Marti E, Tilley P. Comparison of Skin Prick Tests (SPT), Intradermal Tests (IDT) and In Vitro Tests in the Characterization of Insect Bite Hypersensitivity (IBH) in a Population of Lusitano Horses: Contribution for Future Implementation of SPT in IBH Diagnosis. Animals (Basel) 2023 Aug 28;13(17).
    doi: 10.3390/ani13172733pubmed: 37684997google scholar: lookup
  2. Cox A, Stewart AJ. Insect Bite Hypersensitivity in Horses: Causes, Diagnosis, Scoring and New Therapies. Animals (Basel) 2023 Aug 4;13(15).
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  3. Sauvé F. Can equine urticaria be cured?. Can Vet J 2020 Sep;61(9):1001-1004.
    pubmed: 32879529
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    doi: 10.1111/all.13417pubmed: 29350763google scholar: lookup
  6. Marsella R, De Benedetto A. Atopic Dermatitis in Animals and People: An Update and Comparative Review. Vet Sci 2017 Jul 26;4(3).
    doi: 10.3390/vetsci4030037pubmed: 29056696google scholar: lookup
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    doi: 10.1111/all.12726pubmed: 26280544google scholar: lookup
  8. Basile RC, Rivera GG, Del Rio LA, de Bonis TC, do Amaral GP, Giangrecco E, Ferraz G, Yoshinari NH, Canola PA, Queiroz Neto A. Anaphylactoid reaction caused by sodium ceftriaxone in two horses experimentally infected by Borrelia burgdorferi. BMC Vet Res 2015 Aug 12;11:197.
    doi: 10.1186/s12917-015-0478-6pubmed: 26265349google scholar: lookup
  9. Jensen-Jarolim E, Einhorn L, Herrmann I, Thalhammer JG, Panakova L. Pollen Allergies in Humans and their Dogs, Cats and Horses: Differences and Similarities. Clin Transl Allergy 2015;5:15.
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