Use of a novel silk mesh for ventral midline hernioplasty in a mare.
Abstract: Ventral midline hernia formation following abdominal surgery in horses is an uncommon complication; however, it can have serious consequences leading to increased morbidity and mortality. Currently, mesh hernioplasty is the treatment of choice for large ventral midline hernias in horses to allow potential return to normal function. Complications following mesh hernioplasty using polypropylene or polyester mesh in horses can be serious and similar to complications seen in human patients, including persistent incisional drainage, mesh infection, hernia recurrence, intra-abdominal adhesions, mesh or body wall failure, recurrent abdominal pain (colic), and peritonitis. This report describes the use of a novel bioresorbable silk mesh for repair of a large ventral midline incisional hernia in a mature, 600-kg horse. To our knowledge, this is the first report of its kind in the literature. Methods: A 9-year-old, 600-kg Warmblood mare presented with a ventral midline hernia following emergency exploratory celiotomy 20 months prior. The mare was anesthetized and a hernioplasty was performed using a novel bioresorbable silk mesh (SERI(®) Surgical Scaffold; Allergan Medical, Boston, MA). No complications were encountered either intra- or postoperatively. The mare was discharged from the hospital at 3 days postoperatively in an abdominal support bandage. At 8 and 20 weeks postoperatively, ultrasonographic assessment showed evidence of tissue ingrowth within and around the mesh. The mare was able to be bred 2 years in a row, carrying both foals to full gestation with no complications. Following both foalings, the abdomen has maintained a normal contour with no evidence of hernia recurrence. Conclusions: Ventral abdominal hernias can be repaired in horses using a bioresorbable silk mesh, which provides adequate biomechanical strength while allowing for fibrous tissue ingrowth. The use of a bioresorbable silk mesh for the repair of ventral hernias can be considered as a realistic option as it potentially provides significant benefits over traditional non-resorbable mesh.
Publication Date: 2015-03-13 PubMed ID: 25879822PubMed Central: PMC4426545DOI: 10.1186/s12917-015-0379-8Google Scholar: Lookup
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- Case Reports
- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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The researchers studied the use of a new type of bioresorbable silk mesh to treat ventral midline hernias in horses. The study on a single mare achieved successful results with the mesh, suggesting potential benefits over traditional non-resorbable mesh.
Introduction and Background
- Ventral midline hernias are a relatively rare complication in horses after abdominal surgery. However, such complications, when they occur, can be serious, increasing the instances of further health complications and mortality in the affected horses.
- For large ventral midline hernias, the current treatment of choice is mesh hernioplasty, a surgical procedure using a mesh implant to reinforce the weakened area.
- However, the mesh implants often used (made of polypropylene or polyester) can lead to serious complications in human patients and horses. These complications may include persistent incisional drainage, mesh infection, hernia recurrence, intra-abdominal adhesions, mesh or body wall failure, recurrent abdominal pain (colic), and peritonitis.
Methodology and Findings
- The study involved a 9-year-old mare presenting with a ventral midline hernia after emergency exploratory celiotomy 20 months before the treatment.
- The hernia was treated using a new kind of bioresorbable silk mesh (SERI(®) Surgical Scaffold; Allergan Medical, Boston, MA) in a hernioplasty procedure. There were no complications during or after surgery, and the horse was discharged after three days.
- Follow-up ultrasonographic examinations at 8 and 20 weeks post-surgery showed that tissue was growing within and around the mesh.
- Two years post-surgery, the mare successfully bred on two occasions, carrying both foals to full term without any complications and with no incidence of hernia recurrence.
Conclusion
- The results of this single case study suggest that bioresorbable silk mesh can be effectively used to treat ventral abdominal hernias in horses.
- This type of mesh offers sufficient biomechanical strength and allows for fibrous tissue ingrowth, potentially providing certain advantages over traditional non-resorbable mesh.
Significance and Future Research
- This is reportedly the first study of its kind to use bioresorbable silk mesh for ventral midline hernioplasty in a horse.
- Further empirical research, ideally involving larger sample sizes, is recommended to corroborate these findings and fully explore the potential benefits and limitations of this novel treatment method.
Cite This Article
APA
Haupt J, García-López JM, Chope K.
(2015).
Use of a novel silk mesh for ventral midline hernioplasty in a mare.
BMC Vet Res, 11, 58.
https://doi.org/10.1186/s12917-015-0379-8 Publication
Researcher Affiliations
- Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, 200 Westboro Road, North Grafton, MA, 01536, USA. jlhaupt@mit.edu.
- Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, 200 Westboro Road, North Grafton, MA, 01536, USA. jose.garcia-lopez@tufts.edu.
- Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, 200 Westboro Road, North Grafton, MA, 01536, USA. katherine.chope@tufts.edu.
MeSH Terms
- Animals
- Female
- Hernia / veterinary
- Herniorrhaphy / instrumentation
- Herniorrhaphy / veterinary
- Horse Diseases / surgery
- Horses
- Silk
- Surgical Mesh / veterinary
References
This article includes 12 references
- Mair TS, Smith LJ. Survival and complication rates in 300 horses undergoing surgical treatment of colic. Part 2: Short-term complications.. Equine Vet J 2005 Jul;37(4):303-9.
- Mair TS, Smith LJ. Survival and complication rates in 300 horses undergoing surgical treatment of colic. Part 3: Long-term complications and survival.. Equine Vet J 2005 Jul;37(4):310-4.
- Gibson KT, Curtis CR, Turner AS, McIlwraith CW, Aanes WA, Stashak TS. Incisional hernias in the horse. Incidence and predisposing factors.. Vet Surg 1989 Sep-Oct;18(5):360-6.
- French NP, Smith J, Edwards GB, Proudman CJ. Equine surgical colic: risk factors for postoperative complications.. Equine Vet J 2002 Jul;34(5):444-9.
- Elce YA, Kraus BM, Orsini JA. Mesh hernioplasty for repair of incisional hernias of the ventral body wall in large horses.. Equine Vet Educ 2005;17:252–6.
- Kelmer G, Schumacher J. Repair of abdominal wall hernias in horses using primary closure and subcutaneous implantation of mesh.. Vet Rec 2008 Dec 6;163(23):677-9.
- Tulleners EP, Fretz PB. Prosthetic repair of large abdominal wall defects in horses and food animals.. J Am Vet Med Assoc 1983 Feb 1;182(3):258-62.
- Horan RL, Bramono DS, Stanley JR, Simmons Q, Chen J, Boepple HE, Altman GH. Biological and biomechanical assessment of a long-term bioresorbable silk-derived surgical mesh in an abdominal body wall defect model.. Hernia 2009 Apr;13(2):189-99.
- Hawkins JF, Bowman KF, Roberts MC, Cowen P. Peritonitis in horses: 67 cases (1985-1990).. J Am Vet Med Assoc 1993 Jul 15;203(2):284-8.
- Mair TS, Hillyer MH, Taylor FG. Peritonitis in adult horses: a review of 21 cases.. Vet Rec 1990 Jun 9;126(23):567-70.
- Altman GH, Diaz F, Jakuba C, Calabro T, Horan RL, Chen J, Lu H, Richmond J, Kaplan DL. Silk-based biomaterials.. Biomaterials 2003 Feb;24(3):401-16.
- Gross JE, Horan RL, Gaylord M, Olsen RE, McGill LD, García-López JM, Biber K, Barnico K, Toponarski I, Altman G. An evaluation of SERI surgical scaffold for soft-tissue support and repair in an ovine model of two-stage breast reconstruction.. Plast Reconstr Surg 2014 Nov;134(5):700e-704e.
Citations
This article has been cited 3 times.- Yadav I, Kumar R. Surgical repair of indirect inguinal hernia in bonnet macaque (Macaca radiata). Open Vet J 2022 Jul-Aug;12(4):434-438.
- Orlandini CF, Steiner D, Boscarato AG, Gimenes GC, Alberton LR. Surgical treatment of traumatic eventration with polyester button and polypropylene mesh to strengthen the suture technique in equine. BMC Vet Res 2016 Mar 19;12:58.
- Guillaume O, Park J, Monforte X, Gruber-Blum S, Redl H, Petter-Puchner A, Teuschl AH. Fabrication of silk mesh with enhanced cytocompatibility: preliminary in vitro investigation toward cell-based therapy for hernia repair. J Mater Sci Mater Med 2016 Feb;27(2):37.
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