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[Use of biochemical markers of bone metabolism in veterinary medicine].

Abstract: Effective, non-invasive bone assessment methods for screening, diagnosis and follow-up of the skeleton are more and more requested in veterinary medicine. In contrast to clinical parameters, invasive methods and imaging techniques, indices of bone turnover is a tool for bone metabolism evaluation of the whole skeleton. Biochemical bone markers therefore provide a more real-time assessment of the bone status with simple blood- or urine-analysis. This article surveys currently available biochemical marker of bone metabolism used in veterinary medicine. Additionally, information is provided about physiological and pathological, as well as therapeutic variations of biochemical bone marker concentrations in various species.
Publication Date: 2006-09-30 PubMed ID: 17007471
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Summary

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This study assesses the use of biochemical markers of bone metabolism in animals, considering their applications in diagnosis, screening and treatment. The discussed markers provide a more real-time and non-invasive assessment of bone health compared to traditional methods.

Overview of Biochemical Markers in Veterinary Medicine

  • The article starts with a general overview of the application of biochemical markers in veterinary medicine. Unlike clinical parameters, invasive methods, and imaging techniques which provide localized information about bone condition, these markers give a comprehensive view of the whole skeletal metabolism.
  • The authors are suggesting that the use of biochemical markers is much more efficient as it allows real-time evaluation of bone status. This is achieved through simple blood or urine analyses which are less invasive and burdensome for the animal.

Current Biochemical Markers Used in Veterinary Medicine

  • This part of the article discusses the currently available biochemical markers used in the evaluation of bone metabolism in animals. The specifics of each marker are analyzed, providing veterinarians with the information necessary to select the most appropriate tool according to the circumstances.
  • It’s also mentioned that these biochemical markers are not only useful in diagnosing and screening for bone diseases, but also in the follow-up of therapeutic responses.

Physiological and Pathological Variations of Biochemical Bone Markers

  • The article further delves into the variations of concentrations of these biochemical bone markers in physiological and pathological conditions across different animal species. Such information proves to be crucial in interpreting the results and making an accurate diagnosis.
  • Understanding these variations can help in deducing the specific bone condition of the animal, making the diagnosis more accurate and the recommended treatment more targeted.

Therapeutic Variations of Biochemical Bone Markers

  • In addition, the article provides insights into how biochemical bone marker concentrations can change in response to therapy. This underscores their value in monitoring therapeutic effectiveness over time.
  • Through this, the veterinarian can assess whether the current treatment approach is working or if it needs to be adjusted accordingly, supporting a more targeted and effective approach to bone health in animals.

Cite This Article

APA
Carstanjen B. (2006). [Use of biochemical markers of bone metabolism in veterinary medicine]. Berl Munch Tierarztl Wochenschr, 119(9-10), 425-435.

Publication

ISSN: 0005-9366
NlmUniqueID: 0003163
Country: Germany
Language: ger
Volume: 119
Issue: 9-10
Pages: 425-435

Researcher Affiliations

Carstanjen, Bianca
  • Clinique Equine, Ecole Nationale Vétérinaire d'Alfort, Frankreich. carstanjen@t-online.de

MeSH Terms

  • Animal Diseases / diagnosis
  • Animals
  • Biomarkers / analysis
  • Bone Development / physiology
  • Bone Diseases / diagnosis
  • Bone Diseases / veterinary
  • Bone Resorption / diagnosis
  • Bone Resorption / veterinary
  • Bone and Bones / metabolism
  • Osteogenesis / physiology
  • Species Specificity

Citations

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