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Use of sodium monoiodoacetate to fuse the distal hock joints in horses.
Abstract: Intra-articular injection of sodium monoiodoacetate (MIA) was investigated as an agent for chemical arthrodesis of the distal hock joints in the horse. Five horses diagnosed with either spavin (three horses), a small tarsal bone fracture or a failed surgical arthrodesis, had 150 mg of MIA injected into the tarsometatarsal (TMT) joint of the affected hock(s). Eight joints were treated in the five horses. Follow-up evaluation by clinical and radiological examination took place over 9 to 14 months. Two of the five horses were sound at the conclusion of the study and one horse, although lame after flexion, was considered by the owner to have been treated successfully. One of eight TMT joints showed complete radiographic fusion. Complications after treatment included pain, chronic lameness and swelling. It was concluded that chemical arthrodesis using this technique can not be recommended as being a superior treatment as compared with surgical arthrodesis at this time but is deserving of further clinical evaluation.
Publication Date: 1995-01-01 PubMed ID: 8787522DOI: 10.1111/j.1751-0813.1995.tb03471.xGoogle Scholar: Lookup The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
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Summary
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This study explores the use of sodium monoiodoacetate (MIA) to fuse the distal hock joints in horses, a procedure known as chemical arthrodesis. Results suggest that this technique may not be superior to surgical arthrodesis, given observed complications like pain, chronic lameness, and swelling, although further studies are suggested due to some promising outcomes.
Objective and Methodology of the Study
- The main focus of the research was to investigate the effectiveness of sodium monoiodoacetate (MIA) as an agent for chemical arthrodesis, a procedure involving fusion of a joint, of the distal hock joints in horses.
- The study involved five horses with various conditions, including spavin in three horses, a small tarsal bone fracture, or a failed surgical arthrodesis.
- 150 mg of MIA was injected into the tarsometatarsal (TMT) joint of the affected hocks in each horse. In total, eight joints were treated in the five horses.
- The progress of the horses post-treatment was monitored over a period of 9 to 14 months through clinical and radiological examination.
Key Findings and Outcomes
- Two out of the five horses were sound at the end of the study, indicating that they showed no signs of discomfort or lameness.
- Of the remaining horses, one was lame after flexion, but the owner found the treatment successful.
- In terms of the actual fusing of the joint, only one out of the eight TMT joints showed complete radiographic fusion, indicating successful arthrodesis.
- Following the treatment, some horses experienced complications including pain, chronic lameness, and swelling.
Conclusion
- Although this study’s results were mixed, it concludes that chemical arthrodesis, using the technique of MIA injection, cannot be recommended as a superior treatment against surgical arthrodesis for the time being.
- Despite some of the complications observed, the research suggests that the technique warrants further clinical evaluation, given the positive outcomes in some of the cases.
Cite This Article
APA
Sammut EB, Kannegieter NJ.
(1995).
Use of sodium monoiodoacetate to fuse the distal hock joints in horses.
Aust Vet J, 72(1), 25-28.
https://doi.org/10.1111/j.1751-0813.1995.tb03471.x Publication
Researcher Affiliations
- Department of Veterinary Clinical Sciences, University of Sydney, New South Wales.
MeSH Terms
- Animals
- Arthrodesis / methods
- Arthrodesis / veterinary
- Female
- Hindlimb / drug effects
- Hindlimb / injuries
- Horse Diseases / therapy
- Horses / injuries
- Injections, Intra-Articular / veterinary
- Iodoacetates / administration & dosage
- Iodoacetates / therapeutic use
- Iodoacetic Acid
- Male
- Osteoarthritis / therapy
- Osteoarthritis / veterinary
- Treatment Outcome
Citations
This article has been cited 1 times.- Penraat JH, Allen AL, Fretz PB, Bailey JV. An evaluation of chemical arthrodesis of the proximal interphalangeal joint in the horse by using monoiodoacetate. Can J Vet Res 2000 Oct;64(4):212-21.
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