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Australian veterinary journal2013; 91(3); 102-107; doi: 10.1111/avj.12015

Use of ultrasound-guided autologous bone marrow transfer for treatment of suspensory ligament desmitis in 30 race horses (2003-2010).

Abstract: To evaluate the racing performance of horses that underwent ultrasound-guided intralesional injection of autologous bone marrow aspirate for treatment of selected forelimb suspensory ligament (body or branch) core lesions. Methods: Retrospective cohort study of 13 Standardbred and 17 Thoroughbred race horses. Methods: Autologous bone marrow aspirated from the sternebrae was injected, under ultrasound guidance, into suspensory ligament core lesions (body or branch). Racing records were reviewed for a comparison of performance before and after surgery. Results: Of the 13 Standardbreds, 9 (69%) had one or more starts within the follow-up period and 9 (69%) had five or more starts. Of the 17 Thoroughbreds, 15 (88%) had one or more starts within the follow-up period and 12 (71%) had five or more starts. Eight Standardbred horses had at least one start both before and after surgery. Earnings per start did not differ significantly between the three starts immediately after surgery compared with the three starts immediately prior to surgery. Thirteen Thoroughbred horses had at least one start both before and after surgery. Earnings per start were less for the three starts immediately after surgery compared with the three starts immediately prior to surgery. Conclusions: A horse with a core lesion in the branch or body of the suspensory ligament has a good prognosis for return to racing after treatment with intralesional injection of bone marrow aspirate.
Publication Date: 2013-01-29 PubMed ID: 23438462DOI: 10.1111/avj.12015Google Scholar: Lookup
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  • Journal Article

Summary

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The research paper presents an evaluation of the effectiveness of autologous bone marrow injections in treating ligament lesions in racehorses. The study found that afflicted horses demonstrate promising prospects for return to racing after the treatment.

Research Methodology

  • The study involved a retrospective cohort of 30 racehorses, comprised of 13 Standardbreds and 17 Thoroughbreds.
  • In the treatment process, autologous bone marrow was aspirated from the sternebrae (a segment of the horse’s sternum), and subsequently introduced, under ultrasound guidance, into suspensory ligament core lesions.
  • To gauge the treatment’s efficacy, the horses’ racing records were scrutinized to delineate their performance before and after the surgery.

Findings of the Research

  • Out of the 13 Standardbred horses, 9 (69%) managed to participate in at least one race within the post-treatment follow-up period. The same number also succeeded in five or more starts.
  • For the 17 Thoroughbred horses, 15 (88%) partook in at least one race within the follow-up period, and 12 (71%) had five or more starts.
  • There were 8 Standardbred horses and 13 Thoroughbreds that had at least one race both pre and post-surgery.
  • While the earnings per start did not significantly deviate in Standardbreds for the three races following surgery vis-a-vis the three races preceding it, there was a drop in earnings for Thoroughbreds post-surgery.

Conclusions

From the outcome of this study, it was inferred that a horse with a core lesion in the branch or body of the suspensory ligament exhibits a favorable prognosis for a return to racing, following treatment with intralesional injection of bone marrow aspirate. Consequently, the ultrasound-guided autologous bone marrow injection can be considered as a viable therapeutic approach in the treatment of ligament lesions in racehorses.

Cite This Article

APA
Hall MS, Vasey JR, Russell JW, Russell T. (2013). Use of ultrasound-guided autologous bone marrow transfer for treatment of suspensory ligament desmitis in 30 race horses (2003-2010). Aust Vet J, 91(3), 102-107. https://doi.org/10.1111/avj.12015

Publication

ISSN: 1751-0813
NlmUniqueID: 0370616
Country: England
Language: English
Volume: 91
Issue: 3
Pages: 102-107

Researcher Affiliations

Hall, M S
  • Goulburn Valley Equine Hospital, 905 Goulburn Valley Highway, Congupna, Victoria, 3633, Australia. maxhall@gmail.com
Vasey, J R
    Russell, J W
      Russell, T

        MeSH Terms

        • Animals
        • Bone Marrow Transplantation / diagnostic imaging
        • Bone Marrow Transplantation / veterinary
        • Cohort Studies
        • Female
        • Forelimb
        • Horse Diseases / therapy
        • Horses
        • Inflammation / therapy
        • Inflammation / veterinary
        • Injections, Intralesional / veterinary
        • Lameness, Animal
        • Ligaments / pathology
        • Male
        • Retrospective Studies
        • Sports
        • Treatment Outcome
        • Ultrasonography

        Citations

        This article has been cited 2 times.
        1. Martino NA, Reshkin SJ, Ciani E, Dell'Aquila ME. Calcium-sensing receptor-mediated osteogenic and early-stage neurogenic differentiation in umbilical cord matrix mesenchymal stem cells from a large animal model. PLoS One 2014;9(11):e111533.
          doi: 10.1371/journal.pone.0111533pubmed: 25379789google scholar: lookup
        2. Guest DJ, Birch HL, Thorpe CT. A review of the equine suspensory ligament: Injury prone yet understudied. Equine Vet J 2025 Sep;57(5):1167-1182.
          doi: 10.1111/evj.14447pubmed: 39604165google scholar: lookup