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Polish journal of veterinary sciences2014; 17(2); 247-253; doi: 10.2478/pjvs-2014-0035

Usefulness of the assessment of discharge accumulation in the lower airways and tracheal septum thickening in the differential diagnosis of recurrent airway obstruction (RAO) and inflammatory airway disease (IAD) in the horse.

Abstract: The aim of the present study was to use endoscopic evaluation to compare the grade of accumulation of discharge in the lower airways of horses with recurrent airway obstruction (RAO) and inflammatory airway disease (IAD), and to estimate the usefulness of endoscopic evaluation in differential diagnosis of these diseases. Endoscopic evaluation consists of: the amount of discharge in the lower part of the trachea and tracheal bifurcation, and the assessment of tracheal septum thickness. This study was performed on 248 horses, 10 were healthy, 97 were diagnosed as RAO, and 141 were diagnosed as IAD. In all animals both a clinical and endoscopic examination were performed. During endoscopy, a score of mucus accumulation was estimated in 3/4 lower of the trachea and in the tracheal bifurcation. In addition to this, thickening of the tracheal septum was also assessed. According to the results of this study, it was estimated that the accumulation of mucus in the lower airways was much more advanced in RAO horses compared to horses with IAD. In horses with RAO there was a marked thickening of the tracheal septum compared to IAD horses. The results indicate the efficacy of scoring the amount of mucus in the tracheal lumen and tracheal bifurcation, as well as the efficacy of the assessment of tracheal septum thickness in the diagnosis of these diseases.
Publication Date: 2014-07-06 PubMed ID: 24988850DOI: 10.2478/pjvs-2014-0035Google Scholar: Lookup
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  • Journal Article

Summary

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The research focuses on the use of endoscopy to distinguish between recurrent airway obstruction (RAO) and inflammatory airway disease (IAD) in horses. Researchers used this method to assess the amount of discharge in the lower airways and the thickness of the tracheal septum, and concluded that this technique is effective in diagnosing these conditions.

Research Objective

  • The key aim was to differentiate between two equine respiratory disorders, Recurrent Airway Obstruction (RAO) and Inflammatory Airway Disease (IAD), using endoscopic evaluation. Specifically, the study compared the amount of mucus buildup in the lower respiratory tract and the thickness of the tracheal septum.

Methodology

  • The study used a sample size of 248 horses. They were divided into three categories: healthy horses (10), horses with RAO (97), and horses with IAD (141).
  • Each horse underwent both clinical and endoscopic examination. Endoscopy was performed to estimate the degree of mucus accumulation in the lower 3/4 of the trachea and the tracheal bifurcation, as well as to evaluate the thickness of the tracheal septum.

Findings

  • The study found that horses with RAO had a higher degree of mucus buildup in the lower airways compared to those with IAD. Furthermore, substantial thickening of the tracheal septum was noted in horses with RAO, in contrast to those identified with IAD.

Conclusions

  • The findings suggest that scoring the amount of discharge in the tracheal lumen and tracheal bifurcation, as well as assessing the thickness of the tracheal septum, can be effectively employed in diagnosing RAO and IAD. Thus, endoscopic evaluation is a useful tool in the differential diagnosis of these equine respiratory diseases.

Cite This Article

APA
Wysocka B, Kluciński W. (2014). Usefulness of the assessment of discharge accumulation in the lower airways and tracheal septum thickening in the differential diagnosis of recurrent airway obstruction (RAO) and inflammatory airway disease (IAD) in the horse. Pol J Vet Sci, 17(2), 247-253. https://doi.org/10.2478/pjvs-2014-0035

Publication

ISSN: 1505-1773
NlmUniqueID: 101125473
Country: Germany
Language: English
Volume: 17
Issue: 2
Pages: 247-253

Researcher Affiliations

Wysocka, B
    Kluciński, W

      MeSH Terms

      • Animals
      • Female
      • Horse Diseases / diagnosis
      • Horse Diseases / pathology
      • Horses
      • Inflammation / diagnosis
      • Inflammation / pathology
      • Inflammation / veterinary
      • Male
      • Mucus / metabolism
      • Pulmonary Disease, Chronic Obstructive / diagnosis
      • Pulmonary Disease, Chronic Obstructive / pathology
      • Pulmonary Disease, Chronic Obstructive / veterinary
      • Trachea / pathology

      Citations

      This article has been cited 5 times.
      1. Bartenschlager F, Kuropka B, Schmitz P, Dumke F, Landmann K, Gruber AD, Weise C, Schnabel CL, Gehlen H, Mundhenk L. Proteomic profiling of equine airway mucus reveals compositional changes in asthmatic phenotypes. Sci Rep 2026 Feb 10;16(1):5880.
        doi: 10.1038/s41598-026-38766-3pubmed: 41667845google scholar: lookup
      2. Kowalik S, O'reilly M, Niedźwiedź A, Kędzierski W. Equine Asthma Does Not Affect Circulating Myostatin Concentrations in Horses. Animals (Basel) 2024 Mar 4;14(5).
        doi: 10.3390/ani14050799pubmed: 38473184google scholar: lookup
      3. Frippiat T, Art T, Tosi I. Airway Hyperresponsiveness, but Not Bronchoalveolar Inflammatory Cytokines Profiles, Is Modified at the Subclinical Onset of Severe Equine Asthma. Animals (Basel) 2023 Aug 1;13(15).
        doi: 10.3390/ani13152485pubmed: 37570294google scholar: lookup
      4. Sheats MK, Davis KU, Poole JA. Comparative Review of Asthma in Farmers and Horses. Curr Allergy Asthma Rep 2019 Oct 10;19(11):50.
        doi: 10.1007/s11882-019-0882-2pubmed: 31599358google scholar: lookup
      5. Niedzwiedz A, Borowicz H, Januszewska L, Markiewicz-Gorka I, Jaworski Z. Serum 8-hydroxy-2-deoxyguanosine as a marker of DNA oxidative damage in horses with recurrent airway obstruction. Acta Vet Scand 2016 Jun 7;58(1):38.
        doi: 10.1186/s13028-016-0215-6pubmed: 27267076google scholar: lookup