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Schweizer Archiv fur Tierheilkunde2012; 154(12); 513-519; doi: 10.1024/0036-7281/a000400

[Vigilance for veterinary medicinal products: reports of adverse reactions in the year 2011].

Abstract: 167 adverse reactions of Swissmedic-authorized veterinary medicinal products were reported during the year 2011 (2010: 160). Species and drug classes remain comparable with previous years: most of the reactions occurred following the use of antiparasitic products (39 %), antiinfectives (20 %) or non-steroidal antiinflammatory drugs (11 %) in companion animals (85 dogs and 27 cats) followed by cattle/calves (37). We received 15 cases of adverse reactions following reconverted use, 8 of them in treated cats. Additionally the Swiss Toxicological Information Centre in Zürich processed 84 enquiries and transmitted them to Swissmedic. One case of a successful new therapy to treat ivermectin poisoning in a pony is presented. Finally, the vaccinovigilance program received 60 declarations following the application of various vaccines, mainly to dogs or cats.
Publication Date: 2012-11-29 PubMed ID: 23188763DOI: 10.1024/0036-7281/a000400Google Scholar: Lookup
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  • English Abstract
  • Journal Article

Summary

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The research article presents a statistical review of adverse reactions reported in Swiss animals due to veterinary medicinal products in the year 2011. It outlines the types of medications causing reactions, the affected species, and also briefly mentions a new therapy for a specific case of poisoning.

Reported Adverse Reactions in Animals

The research reports on the adverse reactions experienced due to the use of authorized veterinary medicinal products in Switzerland in 2011. A total of 167 adverse reactions were reported, slightly up from 160 in 2010. Specifics include:

  • The types of drugs causing most of these reactions were antiparasitic products, which accounted for 39% of the cases, followed by antiinfectives (20%), and then non-steroidal anti-inflammatory drugs (11%).
  • The species most affected were companion animals, with 85 dogs and 27 cats experiencing adverse reactions. Cattle and calves also experienced a significant number of reactions, with 37 cases reported.

Cases of ReConverted Use

The research additionally highlights cases of reconverted use of these medicines, which refers to when a drug previously taken off the market due to its adverse effects is reused after some revision. In 2011:

  • 15 cases of adverse reactions were reported following reconverted use.
  • Out of these 15 cases, 8 occurred in treated cats.

Swiss Toxicological Information Centre Interactions

The article also reports on interactions between the Swiss Toxicological Information Centre in Zurich and Swissmedic in 2011.

  • The centre processed and transmitted 84 enquires related to these adverse reactions to Swissmedic.

New Therapy for Ivermectin Poisoning

The article mentions that a successful new therapy was introduced for treating ivermectin poisoning in a pony during the year under review.

Vaccinovigilance Program

The research report also provides information about the Swiss vaccinovigilance program in 2011. Specifically,

  • The program received 60 declarations of reactions following the application of various vaccines.
  • These reactions primarily occurred in dogs and cats.

Cite This Article

APA
Müntener CR, Bruckner L, Kupper J, Althaus F, Caduff-Janosa P. (2012). [Vigilance for veterinary medicinal products: reports of adverse reactions in the year 2011]. Schweiz Arch Tierheilkd, 154(12), 513-519. https://doi.org/10.1024/0036-7281/a000400

Publication

ISSN: 0036-7281
NlmUniqueID: 0424247
Country: Switzerland
Language: ger
Volume: 154
Issue: 12
Pages: 513-519

Researcher Affiliations

Müntener, C R
  • Institut für Veterinärpharmakologie und -toxikologie, Universität Zürich, Zürich. cedric.muentener@vetpharm.uzh.ch
Bruckner, L
    Kupper, J
      Althaus, F
        Caduff-Janosa, P

          MeSH Terms

          • Adverse Drug Reaction Reporting Systems
          • Animals
          • Animals, Domestic
          • Anti-Infective Agents / adverse effects
          • Cats
          • Cattle
          • Dogs
          • Horses
          • Switzerland
          • Veterinary Drugs / adverse effects