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Home / Equine Research Bank / Eur J Clin Microbiol Infect Dis / West Nile virus: an overview of its spread in Europe and the...
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2004; 23(3); 147-156; doi: 10.1007/s10096-003-1085-1

West Nile virus: an overview of its spread in Europe and the Mediterranean basin in contrast to its spread in the Americas.

Abstract: West Nile (WN) virus is a mosquito-transmitted flavivirus. It is widely distributed in Africa, the Middle East, Asia, and southern Europe and was recently introduced to North America. Birds are involved in the cycle of transmission as amplifying hosts. Humans and horses are considered accidental dead-end hosts. WN fever was initially considered a minor arbovirosis, usually inducing a nonsymptomatic or a mild flu-like illness in humans, but some cases of encephalitis associated with fatalities were reported in Israel in the 1950s. After two silent decades, several human and equine outbreaks of fatal encephalitis occurred from 1996 to 2000 in Romania, Morocco, Tunisia, Italy, Russia, Israel, and France. In Romania, a few cases of WN encephalitis in humans are noticed every year, and in France, recent WN infections have been detected in monitored sentinel birds in 2001 and 2002. Phylogenetic studies have shown two main lineages of WN strains. Strains from lineage I are present in Africa, India, and Australia and are responsible for the outbreaks in Europe and in the Mediterranean basin, and strains from lineage II have been reported only in sub-Saharan Africa. In 1998, a virulent WN strain from lineage I was identified in dying migrating storks and domestic geese showing clinical symptoms of encephalitis and paralysis in Israel. A nearly identical WN strain suddenly emerged in New York in 1999, killing thousands of native birds and causing fatal cases in humans. The virus is now well established in the New World, and it disseminates rapidly. New modes of transmission through blood donations, organ transplants, and the intrauterine route have been reported. In Europe, an enhanced surveillance of WN infection in humans, horses, birds, and vectors may reveal the presence of the virus in different locations. Nevertheless, outbreaks of WN virus remain unpredictable. Further coordinated studies are needed for a better understanding of the ecology and the pathogenicity of the WN virus.
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Publication Date: 2004-02-19 PubMed ID: 14986160DOI: 10.1007/s10096-003-1085-1Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This study presents an overview of the distribution and impact of West Nile (WN) virus, particularly highlighting its rapid spread in Europe, the Mediterranean basin and the Americas. The research underscores the unpredictable nature of WN virus outbreaks and the need for enhanced surveillance and comprehensive studies for better comprehension of its ecology and pathogenicity.

Understanding West Nile Virus

  • West Nile virus is a flavivirus transmitted primarily by mosquitoes. It is found extensively in Africa, the Middle East, Asia, and southern Europe and has recently been introduced to North America.
  • Birds play a significant role in the transmission cycle, acting as amplifying hosts. Humans and horses, on the other hand, are seen as accidental hosts, usually encountering a dead-end with the virus.

History of Pathogenicity and Spread

  • While WN was initially deemed a minor arbovirosis causing non-symptomatic or mild flu-like illness, cases of fatal encephalitis tied to the virus were reported in Israel in the 1950s.
  • After approximately two decades of relative silence, several outbreaks struck between 1996 and 2000 in Romania, Morocco, Tunisia, Italy, Russia, Israel, and France. These outbreaks comprised notable occurrences of fatal encephalitis in humans and horses.
  • In Romania, cases of WN encephalitis continue to be reported annually. Meanwhile, in France, recent WN infections have been detected in monitored sentinel birds in 2001 and 2002.

Phylogenetic Lineages and Emergence in the Americas

  • The phylogenetic analysis conducted by the researchers identifies two main lineages of WN strains. Lineage I strains, found in Africa, India, and Australia, have been responsible for outbreaks in Europe and the Mediterranean basin. On the other hand, Lineage II strains have only been reported in sub-Saharan Africa.
  • In 1998, a virulent strain originating from Lineage I was identified in migrating storks and domestic geese showing clinical signs of encephalitis and paralysis in Israel.
  • A key highlight of the study was the emergence of an almost identical WN strain in New York in 1999, which resulted in the deaths of thousands of native birds and several fatal cases in humans. This signified the virus’ firm establishment in the Americas and its swift dissemination throughout the region.
  • New modes of transmission through blood donations, organ transplants, and intrauterine exposure were also reported, further complicating the containment and management of the virus.

Monitoring and Future Research

  • The study emphasizes that despite an increased surveillance of WN infection in humans, horses, birds, and vectors in Europe, the outbreaks remain unpredictably sporadic, making it challenging to forecast and control.
  • The authors conclude that further coordinated research efforts are essential to gain a deeper understanding of the virus’s ecology and pathogenicity which can lead to more effective prevention and control strategies.

Cite This Article

APA
Zeller HG, Schuffenecker I. (2004). West Nile virus: an overview of its spread in Europe and the Mediterranean basin in contrast to its spread in the Americas. Eur J Clin Microbiol Infect Dis, 23(3), 147-156. https://doi.org/10.1007/s10096-003-1085-1

Publication

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
ISSN: 0934-9723
NlmUniqueID: 8804297
Country: Germany
Language: English
Volume: 23
Issue: 3
Pages: 147-156

Researcher Affiliations

Zeller, H G
  • Institut Pasteur, National Reference Center for Arboviruses, 21 Avenue Tony Garnier, 69365 Lyon Cedex 07, France. zeller@cervi-lyon.inserm.fr
Schuffenecker, I

    MeSH Terms

    • Americas / epidemiology
    • Animals
    • Classification
    • Disease Outbreaks
    • Disease Reservoirs
    • Europe / epidemiology
    • Female
    • Humans
    • Incidence
    • Infection Control
    • Male
    • Mediterranean Region / epidemiology
    • Risk Factors
    • Survival Rate
    • West Nile Fever / epidemiology
    • West Nile Fever / prevention & control
    • West Nile virus / isolation & purification

    References

    This article includes 90 references
    1. Joubert L, Oudar J, Hannoun C, Beytout D, Corniou B, Guillon JC, Panthier R. [Epidemiology of the West Nile virus: study of a focus in Camargue. IV. Meningo-encephalomyelitis of the horse].. Ann Inst Pasteur (Paris) 1970 Feb;118(2):239-47.
      pubmed: 5461277
    2. Chowers MY, Lang R, Nassar F, Ben-David D, Giladi M, Rubinshtein E, Itzhaki A, Mishal J, Siegman-Igra Y, Kitzes R, Pick N, Landau Z, Wolf D, Bin H, Mendelson E, Pitlik SD, Weinberger M. Clinical characteristics of the West Nile fever outbreak, Israel, 2000.. Emerg Infect Dis 2001 Jul-Aug;7(4):675-8.
      pubmed: 11585531doi: 10.3201/eid0704.010414google scholar: lookup
    3. Bunning ML, Bowen RA, Cropp CB, Sullivan KG, Davis BS, Komar N, Godsey MS, Baker D, Hettler DL, Holmes DA, Biggerstaff BJ, Mitchell CJ. Experimental infection of horses with West Nile virus.. Emerg Infect Dis 2002 Apr;8(4):380-6.
      pubmed: 11971771doi: 10.3201/eid0804.010239google scholar: lookup
    4. Tesh RB, Travassos da Rosa AP, Guzman H, Araujo TP, Xiao SY. Immunization with heterologous flaviviruses protective against fatal West Nile encephalitis.. Emerg Infect Dis 2002 Mar;8(3):245-51.
      pubmed: 11927020doi: 10.3201/eid0803.010238google scholar: lookup
    5. Dupuis AP 2nd, Marra PP, Kramer LD. Serologic evidence of West Nile virus transmission, Jamaica, West Indies.. Emerg Infect Dis 2003 Jul;9(7):860-3.
      pubmed: 12890329doi: 10.3201/eid0907.030249google scholar: lookup
    6. Lvov DK, Butenko AM, Gromashevsky VL, Larichev VP, Gaidamovich SY, Vyshemirsky OI, Zhukov AN, Lazorenko VV, Salko VN, Kovtunov AI, Galimzyanov KM, Platonov AE, Morozova TN, Khutoretskaya NV, Shishkina EO, Skvortsova TM. Isolation of two strains of West Nile virus during an outbreak in southern Russia, 1999.. Emerg Infect Dis 2000 Jul-Aug;6(4):373-6.
      pubmed: 10905970doi: 10.3201/eid0604.000408google scholar: lookup
    7. Deubel V, Fiette L, Gounon P, Drouet MT, Khun H, Huerre M, Banet C, Malkinson M, Desprès P. Variations in biological features of West Nile viruses.. Ann N Y Acad Sci 2001 Dec;951:195-206.
      pubmed: 11797777doi: 10.1111/j.1749-6632.2001.tb02697.xgoogle scholar: lookup
    8. Weiss D, Carr D, Kellachan J, Tan C, Phillips M, Bresnitz E, Layton M. Clinical findings of West Nile virus infection in hospitalized patients, New York and New Jersey, 2000.. Emerg Infect Dis 2001 Jul-Aug;7(4):654-8.
      pubmed: 11589170doi: 10.3201/eid0704.010409google scholar: lookup
    9. Murgue B, Murri S, Zientara S, Durand B, Durand JP, Zeller H. West Nile outbreak in horses in southern France, 2000: the return after 35 years.. Emerg Infect Dis 2001 Jul-Aug;7(4):692-6.
      pubmed: 11585534doi: 10.3201/eid0704.010417google scholar: lookup
    10. Klein C, Kimiagar I, Pollak L, Gandelman-Marton R, Itzhaki A, Milo R, Rabey JM. Neurological features of West Nile virus infection during the 2000 outbreak in a regional hospital in Israel.. J Neurol Sci 2002 Aug 15;200(1-2):63-6.
      pubmed: 12127678doi: 10.1016/s0022-510x(02)00135-1google scholar: lookup
    11. HANNOUN C, PANTHIER R, MOUCHET J, EOUZAN JP. [ISOLATION IN FRANCE OF THE WEST NILE VIRUS FROM PATIENTS AND FROM THE VECTOR CULEX MODESTUS FICALBI].. C R Hebd Seances Acad Sci 1964 Nov 30;259:4170-2.
      pubmed: 14260659
    12. Hubálek Z, Halouzka J. West Nile fever--a reemerging mosquito-borne viral disease in Europe.. Emerg Infect Dis 1999 Sep-Oct;5(5):643-50.
      pubmed: 10511520doi: 10.3201/eid0505.990505google scholar: lookup
    13. MELNICK JL, PAUL JR, RIORDAN JT, BARNETT VH, GOLDBLUM N, ZABIN E. Isolation from human sera in Egypt of a virus apparently identical to West Nile virus.. Proc Soc Exp Biol Med 1951 Aug;77(4):661-5.
      pubmed: 14891830doi: 10.3181/00379727-77-18884google scholar: lookup
    14. Mashimo T, Lucas M, Simon-Chazottes D, Frenkiel MP, Montagutelli X, Ceccaldi PE, Deubel V, Guenet JL, Despres P. A nonsense mutation in the gene encoding 2'-5'-oligoadenylate synthetase/L1 isoform is associated with West Nile virus susceptibility in laboratory mice.. Proc Natl Acad Sci U S A 2002 Aug 20;99(17):11311-6.
      pubmed: 12186974doi: 10.1073/pnas.172195399google scholar: lookup
    15. Jia XY, Briese T, Jordan I, Rambaut A, Chi HC, Mackenzie JS, Hall RA, Scherret J, Lipkin WI. Genetic analysis of West Nile New York 1999 encephalitis virus.. Lancet 1999 Dec 4;354(9194):1971-2.
      pubmed: 10622305doi: 10.1016/s0140-6736(99)05384-2google scholar: lookup
    16. Buckley A, Dawson A, Moss SR, Hinsley SA, Bellamy PE, Gould EA. Serological evidence of West Nile virus, Usutu virus and Sindbis virus infection of birds in the UK.. J Gen Virol 2003 Oct;84(Pt 10):2807-2817.
      pubmed: 13679615doi: 10.1099/vir.0.19341-0google scholar: lookup
    17. Platonov AE, Shipulin GA, Shipulina OY, Tyutyunnik EN, Frolochkina TI, Lanciotti RS, Yazyshina S, Platonova OV, Obukhov IL, Zhukov AN, Vengerov YY, Pokrovskii VI. Outbreak of West Nile virus infection, Volgograd Region, Russia, 1999.. Emerg Infect Dis 2001 Jan-Feb;7(1):128-32.
      pubmed: 11266303doi: 10.3201/eid0701.010118google scholar: lookup
    18. THOMAS LA, EKLUND CM. Overwintering of western equine encephalomyelitis virus in experimentally infected garter snakes and transmission to mosquitoes.. Proc Soc Exp Biol Med 1960 Oct;105:52-5.
      pubmed: 13776510doi: 10.3181/00379727-105-26006google scholar: lookup
    19. Hindiyeh M, Shulman LM, Mendelson E, Weiss L, Grossman Z, Bin H. Isolation and characterization of West Nile virus from the blood of viremic patients during the 2000 outbreak in Israel.. Emerg Infect Dis 2001 Jul-Aug;7(4):748-50.
      pubmed: 11585544doi: 10.3201/eid0704.010428google scholar: lookup
    20. Berthet FX, Zeller HG, Drouet MT, Rauzier J, Digoutte JP, Deubel V. Extensive nucleotide changes and deletions within the envelope glycoprotein gene of Euro-African West Nile viruses.. J Gen Virol 1997 Sep;78 ( Pt 9):2293-7.
      pubmed: 9292017doi: 10.1099/0022-1317-78-9-2293google scholar: lookup
    21. Monath TP, McCarthy K, Bedford P, Johnson CT, Nichols R, Yoksan S, Marchesani R, Knauber M, Wells KH, Arroyo J, Guirakhoo F. Clinical proof of principle for ChimeriVax: recombinant live, attenuated vaccines against flavivirus infections.. Vaccine 2002 Jan 15;20(7-8):1004-18.
      pubmed: 11803060doi: 10.1016/s0264-410x(01)00457-1google scholar: lookup
    22. Campbell GL, Marfin AA, Lanciotti RS, Gubler DJ. West Nile virus.. Lancet Infect Dis 2002 Sep;2(9):519-29.
      pubmed: 12206968doi: 10.1016/s1473-3099(02)00368-7google scholar: lookup
    23. Abbassy MM, Osman M, Marzouk AS. West Nile virus (Flaviviridae:Flavivirus) in experimentally infected Argas ticks (Acari:Argasidae).. Am J Trop Med Hyg 1993 May;48(5):726-37.
      pubmed: 8517492doi: 10.4269/ajtmh.1993.48.726google scholar: lookup
    24. Tardei G, Ruta S, Chitu V, Rossi C, Tsai TF, Cernescu C. Evaluation of immunoglobulin M (IgM) and IgG enzyme immunoassays in serologic diagnosis of West Nile Virus infection.. J Clin Microbiol 2000 Jun;38(6):2232-9.
      pubmed: 10834982doi: 10.1128/JCM.38.6.2232-2239.2000google scholar: lookup
    25. Miller DL, Mauel MJ, Baldwin C, Burtle G, Ingram D, Hines ME 2nd, Frazier KS. West Nile virus in farmed alligators.. Emerg Infect Dis 2003 Jul;9(7):794-9.
      pubmed: 12890319doi: 10.3201/eid0907.030085google scholar: lookup
    26. Guillon JC, Oudar J, Joubert L, Hannoun C. [Histological lesions of the nervous system in West Nile virus infection in horses].. Ann Inst Pasteur (Paris) 1968 Apr;114(4):539-50.
      pubmed: 5691881
    27. . West Nile Virus activity--United States, 2001.. MMWR Morb Mortal Wkly Rep 2002 Jun 14;51(23):497-501.
      pubmed: 12079245
    28. Charles PE, Zeller H, Bonnotte B, Decasimacker AL, Bour JB, Chavanet P, Lorcerie B. Imported West Nile virus infection in Europe.. Emerg Infect Dis 2003 Jun;9(6):750.
      pubmed: 12781022doi: 10.3201/eid0906.020723google scholar: lookup
    29. Cantile C, Di Guardo G, Eleni C, Arispici M. Clinical and neuropathological features of West Nile virus equine encephalomyelitis in Italy.. Equine Vet J 2000 Jan;32(1):31-5.
      pubmed: 10661382doi: 10.2746/042516400777612080google scholar: lookup
    30. Hubálek Z. European experience with the West Nile virus ecology and epidemiology: could it be relevant for the New World?. Viral Immunol 2000;13(4):415-26.
      pubmed: 11192288doi: 10.1089/vim.2000.13.415google scholar: lookup
    31. Weissenböck H, Kolodziejek J, Fragner K, Kuhn R, Pfeffer M, Nowotny N. Usutu virus activity in Austria, 2001-2002.. Microbes Infect 2003 Oct;5(12):1132-6.
      pubmed: 14554255doi: 10.1016/s1286-4579(03)00204-1google scholar: lookup
    32. Lucas M, Mashimo T, Frenkiel MP, Simon-Chazottes D, Montagutelli X, Ceccaldi PE, Guénet JL, Desprès P. Infection of mouse neurones by West Nile virus is modulated by the interferon-inducible 2'-5' oligoadenylate synthetase 1b protein.. Immunol Cell Biol 2003 Jun;81(3):230-6.
      pubmed: 12752688doi: 10.1046/j.1440-1711.2003.01166.xgoogle scholar: lookup
    33. Lanciotti RS, Roehrig JT, Deubel V, Smith J, Parker M, Steele K, Crise B, Volpe KE, Crabtree MB, Scherret JH, Hall RA, MacKenzie JS, Cropp CB, Panigrahy B, Ostlund E, Schmitt B, Malkinson M, Banet C, Weissman J, Komar N, Savage HM, Stone W, McNamara T, Gubler DJ. Origin of the West Nile virus responsible for an outbreak of encephalitis in the northeastern United States.. Science 1999 Dec 17;286(5448):2333-7.
      pubmed: 10600742doi: 10.1126/science.286.5448.2333google scholar: lookup
    34. Lanciotti RS, Kerst AJ, Nasci RS, Godsey MS, Mitchell CJ, Savage HM, Komar N, Panella NA, Allen BC, Volpe KE, Davis BS, Roehrig JT. Rapid detection of west nile virus from human clinical specimens, field-collected mosquitoes, and avian samples by a TaqMan reverse transcriptase-PCR assay.. J Clin Microbiol 2000 Nov;38(11):4066-71.
      pubmed: 11060069doi: 10.1128/JCM.38.11.4066-4071.2000google scholar: lookup
    35. Baqar S, Hayes CG, Murphy JR, Watts DM. Vertical transmission of West Nile virus by Culex and Aedes species mosquitoes.. Am J Trop Med Hyg 1993 Jun;48(6):757-62.
      pubmed: 8333569doi: 10.4269/ajtmh.1993.48.757google scholar: lookup
    36. Miller BR, Nasci RS, Godsey MS, Savage HM, Lutwama JJ, Lanciotti RS, Peters CJ. First field evidence for natural vertical transmission of West Nile virus in Culex univittatus complex mosquitoes from Rift Valley province, Kenya.. Am J Trop Med Hyg 2000 Feb;62(2):240-6.
      pubmed: 10813479doi: 10.4269/ajtmh.2000.62.240google scholar: lookup
    37. Leis AA, Stokic DS, Polk JL, Dostrow V, Winkelmann M. A poliomyelitis-like syndrome from West Nile virus infection.. N Engl J Med 2002 Oct 17;347(16):1279-80.
      pubmed: 12270971doi: 10.1056/NEJM2002c021587google scholar: lookup
    38. Beasley DW, Li L, Suderman MT, Barrett AD. Mouse neuroinvasive phenotype of West Nile virus strains varies depending upon virus genotype.. Virology 2002 Apr 25;296(1):17-23.
      pubmed: 12036314doi: 10.1006/viro.2002.1372google scholar: lookup
    39. Weissenböck H, Kolodziejek J, Url A, Lussy H, Rebel-Bauder B, Nowotny N. Emergence of Usutu virus, an African mosquito-borne flavivirus of the Japanese encephalitis virus group, central Europe.. Emerg Infect Dis 2002 Jul;8(7):652-6.
      pubmed: 12095429doi: 10.3201/eid0807.020094google scholar: lookup
    40. Davis BS, Chang GJ, Cropp B, Roehrig JT, Martin DA, Mitchell CJ, Bowen R, Bunning ML. West Nile virus recombinant DNA vaccine protects mouse and horse from virus challenge and expresses in vitro a noninfectious recombinant antigen that can be used in enzyme-linked immunosorbent assays.. J Virol 2001 May;75(9):4040-7.
      pubmed: 11287553doi: 10.1128/JVI.75.9.4040-4047.2001google scholar: lookup
    41. Cernescu C, Ruţă SM, Târdei G, Grancea C, Moldoveanu L, Spulbăr E, Tsai T. A high number of severe neurologic clinical forms during an epidemic of West Nile virus infection.. Rom J Virol 1997 Jan-Dec;48(1-4):13-25.
      pubmed: 9836324
    42. Anderson JF, Andreadis TG, Vossbrinck CR, Tirrell S, Wakem EM, French RA, Garmendia AE, Van Kruiningen HJ. Isolation of West Nile virus from mosquitoes, crows, and a Cooper's hawk in Connecticut.. Science 1999 Dec 17;286(5448):2331-3.
      pubmed: 10600741doi: 10.1126/science.286.5448.2331google scholar: lookup
    43. Turell MJ, Bunning M, Ludwig GV, Ortman B, Chang J, Speaker T, Spielman A, McLean R, Komar N, Gates R, McNamara T, Creekmore T, Farley L, Mitchell CJ. DNA vaccine for West Nile virus infection in fish crows (Corvus ossifragus).. Emerg Infect Dis 2003 Sep;9(9):1077-81.
      pubmed: 14519243doi: 10.3201/eid0909.030025google scholar: lookup
    44. Le Guenno B, Bougermouh A, Azzam T, Bouakaz R. West Nile: a deadly virus?. Lancet 1996 Nov 9;348(9037):1315.
      pubmed: 8909403doi: 10.1016/s0140-6736(05)65799-6google scholar: lookup
    45. Burt FJ, Grobbelaar AA, Leman PA, Anthony FS, Gibson GV, Swanepoel R. Phylogenetic relationships of southern African West Nile virus isolates.. Emerg Infect Dis 2002 Aug;8(8):820-6.
      pubmed: 12141968doi: 10.3201/eid0808.020027google scholar: lookup
    46. Tsai TF, Popovici F, Cernescu C, Campbell GL, Nedelcu NI. West Nile encephalitis epidemic in southeastern Romania.. Lancet 1998 Sep 5;352(9130):767-71.
      pubmed: 9737281doi: 10.1016/s0140-6736(98)03538-7google scholar: lookup
    47. . Intrauterine West Nile virus infection--New York, 2002.. MMWR Morb Mortal Wkly Rep 2002 Dec 20;51(50):1135-6.
      pubmed: 12537289
    48. HURLBUT HS, RIZK F, TAYLOR RM, WORK TH. A study of the ecology of West Nile virus in Egypt.. Am J Trop Med Hyg 1956 Jul;5(4):579-620.
      pubmed: 13354882doi: 10.4269/ajtmh.1956.5.579google scholar: lookup
    49. Pealer LN, Marfin AA, Petersen LR, Lanciotti RS, Page PL, Stramer SL, Stobierski MG, Signs K, Newman B, Kapoor H, Goodman JL, Chamberland ME. Transmission of West Nile virus through blood transfusion in the United States in 2002.. N Engl J Med 2003 Sep 25;349(13):1236-45.
      pubmed: 14500806doi: 10.1056/NEJMoa030969google scholar: lookup
    50. Cernescu C, Nedelcu NI, Tardei G, Ruta S, Tsai TF. Continued transmission of West Nile virus to humans in southeastern Romania, 1997-1998.. J Infect Dis 2000 Feb;181(2):710-2.
      pubmed: 10669359doi: 10.1086/315225google scholar: lookup
    51. Bernard KA, Maffei JG, Jones SA, Kauffman EB, Ebel G, Dupuis AP 2nd, Ngo KA, Nicholas DC, Young DM, Shi PY, Kulasekera VL, Eidson M, White DJ, Stone WB, Kramer LD. West Nile virus infection in birds and mosquitoes, New York State, 2000.. Emerg Infect Dis 2001 Jul-Aug;7(4):679-85.
      pubmed: 11585532doi: 10.3201/eid0704.010415google scholar: lookup
    52. George S, Gourie-Devi M, Rao JA, Prasad SR, Pavri KM. Isolation of West Nile virus from the brains of children who had died of encephalitis.. Bull World Health Organ 1984;62(6):879-82.
      pubmed: 6099760
    53. . Detection of West Nile virus in blood donations--United States, 2003.. MMWR Morb Mortal Wkly Rep 2003 Aug 15;52(32):769-72.
      pubmed: 12917583
    54. Huang C, Slater B, Rudd R, Parchuri N, Hull R, Dupuis M, Hindenburg A. First Isolation of West Nile virus from a patient with encephalitis in the United States.. Emerg Infect Dis 2002 Dec;8(12):1367-71.
      pubmed: 12498649doi: 10.3201/eid0812.020532google scholar: lookup
    55. Lichtensteiger CA, Heinz-Taheny K, Osborne TS, Novak RJ, Lewis BA, Firth ML. West Nile virus encephalitis and myocarditis in wolf and dog.. Emerg Infect Dis 2003 Oct;9(10):1303-6.
      pubmed: 14609468doi: 10.3201/eid0910.020617google scholar: lookup
    56. McIntosh BM, Dickinson DB, McGillivray GM. Ecological studies on Sindbis and West Nile viruses in South Africa. V. The response of birds to inoculation of virus.. S Afr J Med Sci 1969 Oct;34(3):77-82.
      pubmed: 5392770
    57. Autorino GL, Battisti A, Deubel V, Ferrari G, Forletta R, Giovannini A, Lelli R, Murri S, Scicluna MT. West Nile virus epidemic in horses, Tuscany region, Italy.. Emerg Infect Dis 2002 Dec;8(12):1372-8.
      pubmed: 12498650doi: 10.3201/eid0812.020234google scholar: lookup
    58. Murgue B, Murri S, Triki H, Deubel V, Zeller HG. West Nile in the Mediterranean basin: 1950-2000.. Ann N Y Acad Sci 2001 Dec;951:117-26.
      pubmed: 11797769doi: 10.1111/j.1749-6632.2001.tb02690.xgoogle scholar: lookup
    59. Steele KE, Linn MJ, Schoepp RJ, Komar N, Geisbert TW, Manduca RM, Calle PP, Raphael BL, Clippinger TL, Larsen T, Smith J, Lanciotti RS, Panella NA, McNamara TS. Pathology of fatal West Nile virus infections in native and exotic birds during the 1999 outbreak in New York City, New York.. Vet Pathol 2000 May;37(3):208-24.
      pubmed: 10810985doi: 10.1354/vp.37-3-208google scholar: lookup
    60. Durand B, Chevalier V, Pouillot R, Labie J, Marendat I, Murgue B, Zeller H, Zientara S. West Nile virus outbreak in horses, southern France, 2000: results of a serosurvey.. Emerg Infect Dis 2002 Aug;8(8):777-82.
      pubmed: 12141961doi: 10.3201/eid0808.010486google scholar: lookup
    61. Malkinson M, Banet C. The role of birds in the ecology of West Nile virus in Europe and Africa.. Curr Top Microbiol Immunol 2002;267:309-22.
      pubmed: 12082995doi: 10.1007/978-3-642-59403-8_15google scholar: lookup
    62. Dohm DJ, Sardelis MR, Turell MJ. Experimental vertical transmission of West Nile virus by Culex pipiens (Diptera: Culicidae).. J Med Entomol 2002 Jul;39(4):640-4.
      pubmed: 12144296doi: 10.1603/0022-2585-39.4.640google scholar: lookup
    63. Pantheir R, Hannoun C, Oudar J, Beytout D, Corniou B, Joubert L, Guillon JC, Mouchet J. [Isolation of West Nile virus in a Camarge horse with encephalomyelitis].. C R Acad Hebd Seances Acad Sci D 1966 Mar 14;262(11):1308-10.
      pubmed: 4956435
    64. Roehrig JT, Nash D, Maldin B, Labowitz A, Martin DA, Lanciotti RS, Campbell GL. Persistence of virus-reactive serum immunoglobulin m antibody in confirmed west nile virus encephalitis cases.. Emerg Infect Dis 2003 Mar;9(3):376-9.
      pubmed: 12643836doi: 10.3201/eid0903.020531google scholar: lookup
    65. Malkinson M, Banet C, Weisman Y, Pokamunski S, King R, Drouet MT, Deubel V. Introduction of West Nile virus in the Middle East by migrating white storks.. Emerg Infect Dis 2002 Apr;8(4):392-7.
      pubmed: 11971773doi: 10.3201/eid0804.010217google scholar: lookup
    66. Komar O, Robbins MB, Klenk K, Blitvich BJ, Marlenee NL, Burkhalter KL, Gubler DJ, Gonzálvez G, Peña CJ, Peterson AT, Komar N. West Nile virus transmission in resident birds, Dominican Republic.. Emerg Infect Dis 2003 Oct;9(10):1299-302.
      pubmed: 14609467doi: 10.3201/eid0910.030222google scholar: lookup
    67. Garmendia AE, Van Kruiningen HJ, French RA, Anderson JF, Andreadis TG, Kumar A, West AB. Recovery and identification of West Nile virus from a hawk in winter.. J Clin Microbiol 2000 Aug;38(8):3110-1.
      pubmed: 10921991doi: 10.1128/JCM.38.8.3110-3111.2000google scholar: lookup
    68. Komar N, Langevin S, Hinten S, Nemeth N, Edwards E, Hettler D, Davis B, Bowen R, Bunning M. Experimental infection of North American birds with the New York 1999 strain of West Nile virus.. Emerg Infect Dis 2003 Mar;9(3):311-22.
      pubmed: 12643825doi: 10.3201/eid0903.020628google scholar: lookup
    69. Loroño-Pino MA, Blitvich BJ, Farfán-Ale JA, Puerto FI, Blanco JM, Marlenee NL, Rosado-Paredes EP, García-Rejón JE, Gubler DJ, Calisher CH, Beaty BJ. Serologic evidence of West Nile virus infection in horses, Yucatan State, Mexico.. Emerg Infect Dis 2003 Jul;9(7):857-9.
      pubmed: 12890328doi: 10.3201/eid0907.030167google scholar: lookup
    70. Murgue B, Zeller H, Deubel V. The ecology and epidemiology of West Nile virus in Africa, Europe and Asia.. Curr Top Microbiol Immunol 2002;267:195-221.
      pubmed: 12082990doi: 10.1007/978-3-642-59403-8_10google scholar: lookup
    71. WORK TH, HURLBUT HS, TAYLOR RM. Indigenous wild birds of the Nile Delta as potential West Nile virus circulating reservoirs.. Am J Trop Med Hyg 1955 Sep;4(5):872-88.
      pubmed: 13259011doi: 10.4269/ajtmh.1955.4.872google scholar: lookup
    72. Sampson BA, Ambrosi C, Charlot A, Reiber K, Veress JF, Armbrustmacher V. The pathology of human West Nile Virus infection.. Hum Pathol 2000 May;31(5):527-31.
      pubmed: 10836291doi: 10.1053/hp.2000.8047google scholar: lookup
    73. Ahmed S, Libman R, Wesson K, Ahmed F, Einberg K. Guillain-Barré syndrome: An unusual presentation of West Nile virus infection.. Neurology 2000 Jul 12;55(1):144-6.
      pubmed: 10891928doi: 10.1212/wnl.55.1.144google scholar: lookup

    Citations

    This article has been cited 145 times.
    1. Hassanien RT, Hussein HA, Abdelmegeed HK, Abdelwahed DA, Khattab OM, Ali MH, Habashi AR, Ibraheem EM, Shahein MA, Abohatab EM. West Nile virus: The current situation in Egypt. Vet World 2023 May;16(5):1154-1160.
      doi: 10.14202/vetworld.2023.1154-1160pubmed: 37576775google scholar: lookup
    2. Pervanidou D, Kefaloudi CN, Vakali A, Tsakalidou O, Karatheodorou M, Tsioka K, Evangelidou M, Mellou K, Pappa S, Stoikou K, Bakaloudi V, Koliopoulos G, Stamoulis K, Patsoula E, Politis C, Hadjichristodoulou C, Papa A. The 2022 West Nile Virus Season in Greece; A Quite Intense Season. Viruses 2023 Jun 29;15(7).
      doi: 10.3390/v15071481pubmed: 37515168google scholar: lookup
    3. Gothe LMR, Ganzenberg S, Ziegler U, Obiegala A, Lohmann KL, Sieg M, Vahlenkamp TW, Groschup MH, Hörügel U, Pfeffer M. Horses as Sentinels for the Circulation of Flaviviruses in Eastern-Central Germany. Viruses 2023 Apr 30;15(5).
      doi: 10.3390/v15051108pubmed: 37243194google scholar: lookup
    4. Fesce E, Marini G, Rosà R, Lelli D, Cerioli MP, Chiari M, Farioli M, Ferrari N. Understanding West Nile virus transmission: Mathematical modelling to quantify the most critical parameters to predict infection dynamics. PLoS Negl Trop Dis 2023 May;17(5):e0010252.
      doi: 10.1371/journal.pntd.0010252pubmed: 37126524google scholar: lookup
    5. Defaye B, Moutailler S, Vollot B, Galon C, Gonzalez G, Moraes RA, Leoncini AS, Rataud A, Le Guillou G, Pasqualini V, Quilichini Y. Detection of Pathogens and Ticks on Sedentary and Migratory Birds in Two Corsican Wetlands (France, Mediterranean Area). Microorganisms 2023 Mar 28;11(4).
      doi: 10.3390/microorganisms11040869pubmed: 37110292google scholar: lookup
    6. M'ghirbi Y, Mousson L, Moutailler S, Lecollinet S, Amaral R, Beck C, Aounallah H, Amara M, Chabchoub A, Rhim A, Failloux AB, Bouattour A. West Nile, Sindbis and Usutu Viruses: Evidence of Circulation in Mosquitoes and Horses in Tunisia. Pathogens 2023 Feb 21;12(3).
      doi: 10.3390/pathogens12030360pubmed: 36986282google scholar: lookup
    7. Ndione MHD, Ndiaye EH, Faye M, Diagne MM, Diallo D, Diallo A, Sall AA, Loucoubar C, Faye O, Diallo M, Faye O, Barry MA, Fall G. Re-Introduction of West Nile Virus Lineage 1 in Senegal from Europe and Subsequent Circulation in Human and Mosquito Populations between 2012 and 2021. Viruses 2022 Dec 6;14(12).
      doi: 10.3390/v14122720pubmed: 36560724google scholar: lookup
    8. Cavalleri JV, Korbacska-Kutasi O, Leblond A, Paillot R, Pusterla N, Steinmann E, Tomlinson J. European College of Equine Internal Medicine consensus statement on equine flaviviridae infections in Europe. J Vet Intern Med 2022 Nov;36(6):1858-1871.
      doi: 10.1111/jvim.16581pubmed: 36367340google scholar: lookup
    9. Nikookar SH, Fazeli-Dinan M, Enayati A. Population Fluctuations and Abundance Indices of Mosquitoes (Diptera: Culicid), as the Potential Bridge Vectors of Pathogens to Humans and Animals in Mazandaran Province, Northern Iran. J Arthropod Borne Dis 2021 Jun;15(2):207-224.
      doi: 10.18502/jad.v15i2.7490pubmed: 35111859google scholar: lookup
    10. Srihi H, Chatti N, Ben Mhadheb M, Gharbi J, Abid N. Phylodynamic and phylogeographic analysis of the complete genome of the West Nile virus lineage 2 (WNV-2) in the Mediterranean basin. BMC Ecol Evol 2021 Sep 27;21(1):183.
      doi: 10.1186/s12862-021-01902-wpubmed: 34579648google scholar: lookup
    11. Vilibic-Cavlek T, Savic V, Klobucar A, Ferenc T, Ilic M, Bogdanic M, Tabain I, Stevanovic V, Santini M, Curman Posavec M, Petrinic S, Benvin I, Ferencak I, Rozac V, Barbic L. Emerging Trends in the West Nile Virus Epidemiology in Croatia in the 'One Health' Context, 2011-2020. Trop Med Infect Dis 2021 Jul 24;6(3).
      doi: 10.3390/tropicalmed6030140pubmed: 34449731google scholar: lookup
    12. Knox A, Beddoe T. Isothermal Nucleic Acid Amplification Technologies for the Detection of Equine Viral Pathogens. Animals (Basel) 2021 Jul 20;11(7).
      doi: 10.3390/ani11072150pubmed: 34359278google scholar: lookup
    13. Ferraguti M, Martínez-de la Puente J, Figuerola J. Ecological Effects on the Dynamics of West Nile Virus and Avian Plasmodium: The Importance of Mosquito Communities and Landscape. Viruses 2021 Jun 23;13(7).
      doi: 10.3390/v13071208pubmed: 34201673google scholar: lookup
    14. Ferraguti M, Martínez-de la Puente J, Jiménez-Clavero MÁ, Llorente F, Roiz D, Ruiz S, Soriguer R, Figuerola J. A field test of the dilution effect hypothesis in four avian multi-host pathogens. PLoS Pathog 2021 Jun;17(6):e1009637.
      doi: 10.1371/journal.ppat.1009637pubmed: 34161394google scholar: lookup
    15. Khan MT, Islam R, Jerin TJ, Mahmud A, Khatun S, Kobir A, Islam MN, Akter A, Mondal SI. Immunoinformatics and molecular dynamics approaches: Next generation vaccine design against West Nile virus. PLoS One 2021;16(6):e0253393.
      doi: 10.1371/journal.pone.0253393pubmed: 34138958google scholar: lookup
    16. Casimiro-Soriguer CS, Perez-Florido J, Fernandez-Rueda JL, Pedrosa-Corral I, Guillot-Sulay V, Lorusso N, Martinez-Gonzalez LJ, Navarro-Marí JM, Dopazo J, Sanbonmatsu-Gámez S. Phylogenetic Analysis of the 2020 West Nile Virus (WNV) Outbreak in Andalusia (Spain). Viruses 2021 May 5;13(5).
      doi: 10.3390/v13050836pubmed: 34063166google scholar: lookup
    17. Fiacre L, Pagès N, Albina E, Richardson J, Lecollinet S, Gonzalez G. Molecular Determinants of West Nile Virus Virulence and Pathogenesis in Vertebrate and Invertebrate Hosts. Int J Mol Sci 2020 Nov 30;21(23).
      doi: 10.3390/ijms21239117pubmed: 33266206google scholar: lookup
    18. Holicki CM, Michel F, Vasić A, Fast C, Eiden M, Răileanu C, Kampen H, Werner D, Groschup MH, Ziegler U. Pathogenicity of West Nile Virus Lineage 1 to German Poultry. Vaccines (Basel) 2020 Sep 5;8(3).
      doi: 10.3390/vaccines8030507pubmed: 32899581google scholar: lookup
    19. Pervanidou D, Vakali A, Georgakopoulou T, Panagiotopoulos T, Patsoula E, Koliopoulos G, Politis C, Stamoulis K, Gavana E, Pappa S, Mavrouli M, Emmanouil M, Sourvinos G, Mentis A, Tsakris A, Hadjichristodoulou C, Tsiodras S, Papa A. West Nile virus in humans, Greece, 2018: the largest seasonal number of cases, 9 years after its emergence in the country. Euro Surveill 2020 Aug;25(32).
      doi: 10.2807/1560-7917.ES.2020.25.32.1900543pubmed: 32794446google scholar: lookup
    20. Fornasiero D, Mazzucato M, Barbujani M, Montarsi F, Capelli G, Mulatti P. Inter-annual variability of the effects of intrinsic and extrinsic drivers affecting West Nile virus vector Culex pipiens population dynamics in northeastern Italy. Parasit Vectors 2020 May 29;13(1):271.
      doi: 10.1186/s13071-020-04143-wpubmed: 32471479google scholar: lookup
    21. Kampen H, Holicki CM, Ziegler U, Groschup MH, Tews BA, Werner D. West Nile Virus Mosquito Vectors (Diptera: Culicidae) in Germany. Viruses 2020 Apr 28;12(5).
      doi: 10.3390/v12050493pubmed: 32354202google scholar: lookup
    22. Onoja AB, Maina MM, Opayele AV. Molecular Identification and Phylogenetic Analysis of Acetylcholinesterase-2 Gene From Culex pipiens And Culex quinquefasciatus (Diptera: Culicine) in Nigeria. Niger Vet J 2018;39(4):285-294.
      pubmed: 32095033
    23. Kövér L, Lengyel S, Takenaka M, Kirchmeir A, Uhl F, Miller R, Schwab C. Why do zoos attract crows? A comparative study from Europe and Asia. Ecol Evol 2019 Dec;9(24):14465-14475.
      doi: 10.1002/ece3.5881pubmed: 31938533google scholar: lookup
    24. Marini G, Calzolari M, Angelini P, Bellini R, Bellini S, Bolzoni L, Torri D, Defilippo F, Dorigatti I, Nikolay B, Pugliese A, Rosà R, Tamba M. A quantitative comparison of West Nile virus incidence from 2013 to 2018 in Emilia-Romagna, Italy. PLoS Negl Trop Dis 2020 Jan;14(1):e0007953.
      doi: 10.1371/journal.pntd.0007953pubmed: 31895933google scholar: lookup
    25. Lecollinet S, Pronost S, Coulpier M, Beck C, Gonzalez G, Leblond A, Tritz P. Viral Equine Encephalitis, a Growing Threat to the Horse Population in Europe?. Viruses 2019 Dec 24;12(1).
      doi: 10.3390/v12010023pubmed: 31878129google scholar: lookup
    26. Wong SH, Jassey A, Wang JY, Wang WC, Liu CH, Lin LT. Virus-Like Particle Systems for Vaccine Development against Viruses in the Flaviviridae Family. Vaccines (Basel) 2019 Sep 20;7(4).
      doi: 10.3390/vaccines7040123pubmed: 31547131google scholar: lookup
    27. Zannoli S, Sambri V. West Nile Virus and Usutu Virus Co-Circulation in Europe: Epidemiology and Implications. Microorganisms 2019 Jun 26;7(7).
      doi: 10.3390/microorganisms7070184pubmed: 31248051google scholar: lookup
    28. Akıner MM, Öztürk M, Başer AB, Günay F, Hacıoğlu S, Brinkmann A, Emanet N, Alten B, Özkul A, Nitsche A, Linton YM, Ergünay K. Arboviral screening of invasive Aedes species in northeastern Turkey: West Nile virus circulation and detection of insect-only viruses. PLoS Negl Trop Dis 2019 May;13(5):e0007334.
      doi: 10.1371/journal.pntd.0007334pubmed: 31059502google scholar: lookup
    29. Jánová E. Emerging and threatening vector-borne zoonoses in the world and in Europe: a brief update. Pathog Glob Health 2019 Mar;113(2):49-57.
      doi: 10.1080/20477724.2019.1598127pubmed: 30916639google scholar: lookup
    30. Ewing DA, Purse BV, Cobbold CA, Schäfer SM, White SM. Uncovering mechanisms behind mosquito seasonality by integrating mathematical models and daily empirical population data: Culex pipiens in the UK. Parasit Vectors 2019 Feb 7;12(1):74.
      doi: 10.1186/s13071-019-3321-2pubmed: 30732629google scholar: lookup
    31. Marini G, Rosà R, Pugliese A, Rizzoli A, Rizzo C, Russo F, Montarsi F, Capelli G. West Nile virus transmission and human infection risk in Veneto (Italy): a modelling analysis. Sci Rep 2018 Sep 18;8(1):14005.
      doi: 10.1038/s41598-018-32401-6pubmed: 30228340google scholar: lookup
    32. Haussig JM, Young JJ, Gossner CM, Mezei E, Bella A, Sirbu A, Pervanidou D, Drakulovic MB, Sudre B. Early start of the West Nile fever transmission season 2018 in Europe. Euro Surveill 2018 Aug;23(32).
      doi: 10.2807/1560-7917.ES.2018.23.32.1800428pubmed: 30107869google scholar: lookup
    33. Sule WF, Oluwayelu DO, Hernández-Triana LM, Fooks AR, Venter M, Johnson N. Epidemiology and ecology of West Nile virus in sub-Saharan Africa. Parasit Vectors 2018 Jul 13;11(1):414.
      doi: 10.1186/s13071-018-2998-ypubmed: 30005653google scholar: lookup
    34. Martínez-de la Puente J, Ferraguti M, Ruiz S, Roiz D, Llorente F, Pérez-Ramírez E, Jiménez-Clavero MÁ, Soriguer R, Figuerola J. Mosquito community influences West Nile virus seroprevalence in wild birds: implications for the risk of spillover into human populations. Sci Rep 2018 Feb 8;8(1):2599.
      doi: 10.1038/s41598-018-20825-zpubmed: 29422507google scholar: lookup
    35. Tmimi FZ, Faraj C, Bkhache M, Mounaji K, Failloux AB, Sarih M. Insecticide resistance and target site mutations (G119S ace-1 and L1014F kdr) of Culex pipiens in Morocco. Parasit Vectors 2018 Jan 22;11(1):51.
      doi: 10.1186/s13071-018-2625-ypubmed: 29357900google scholar: lookup
    36. Carrasco-Hernandez R, Jácome R, López Vidal Y, Ponce de León S. Are RNA Viruses Candidate Agents for the Next Global Pandemic? A Review. ILAR J 2017 Dec 15;58(3):343-358.
      doi: 10.1093/ilar/ilx026pubmed: 28985316google scholar: lookup
    37. Soltész Z, Erdélyi K, Bakonyi T, Barna M, Szentpáli-Gavallér K, Solt S, Horváth É, Palatitz P, Kotymán L, Dán Á, Papp L, Harnos A, Fehérvári P. West Nile virus host-vector-pathogen interactions in a colonial raptor. Parasit Vectors 2017 Sep 29;10(1):449.
      doi: 10.1186/s13071-017-2394-zpubmed: 28962629google scholar: lookup
    38. Al-Jabi SW. Global research trends in West Nile virus from 1943 to 2016: a bibliometric analysis. Global Health 2017 Aug 3;13(1):55.
      doi: 10.1186/s12992-017-0284-ypubmed: 28774315google scholar: lookup
    39. Vogels CBF, Hartemink N, Koenraadt CJM. Modelling West Nile virus transmission risk in Europe: effect of temperature and mosquito biotypes on the basic reproduction number. Sci Rep 2017 Jul 10;7(1):5022.
      doi: 10.1038/s41598-017-05185-4pubmed: 28694450google scholar: lookup
    40. Zehender G, Veo C, Ebranati E, Carta V, Rovida F, Percivalle E, Moreno A, Lelli D, Calzolari M, Lavazza A, Chiapponi C, Baioni L, Capelli G, Ravagnan S, Da Rold G, Lavezzo E, Palù G, Baldanti F, Barzon L, Galli M. Reconstructing the recent West Nile virus lineage 2 epidemic in Europe and Italy using discrete and continuous phylogeography. PLoS One 2017;12(7):e0179679.
      doi: 10.1371/journal.pone.0179679pubmed: 28678837google scholar: lookup
    41. Failloux AB, Bouattour A, Faraj C, Gunay F, Haddad N, Harrat Z, Jancheska E, Kanani K, Kenawy MA, Kota M, Pajovic I, Paronyan L, Petric D, Sarih M, Sawalha S, Shaibi T, Sherifi K, Sulesco T, Velo E, Gaayeb L, Victoir K, Robert V. Surveillance of Arthropod-Borne Viruses and Their Vectors in the Mediterranean and Black Sea Regions Within the MediLabSecure Network. Curr Trop Med Rep 2017;4(1):27-39.
      doi: 10.1007/s40475-017-0101-ypubmed: 28386524google scholar: lookup
    42. Marini G, Guzzetta G, Baldacchino F, Arnoldi D, Montarsi F, Capelli G, Rizzoli A, Merler S, Rosà R. The effect of interspecific competition on the temporal dynamics of Aedes albopictus and Culex pipiens. Parasit Vectors 2017 Feb 23;10(1):102.
      doi: 10.1186/s13071-017-2041-8pubmed: 28228159google scholar: lookup
    43. Grubaugh ND, Andersen KG. Navigating the Zika panic. F1000Res 2016;5:1914.
      doi: 10.12688/f1000research.9370.1pubmed: 27746903google scholar: lookup
    44. Cotar AI, Falcuta E, Prioteasa LF, Dinu S, Ceianu CS, Paz S. Transmission Dynamics of the West Nile Virus in Mosquito Vector Populations under the Influence of Weather Factors in the Danube Delta, Romania. Ecohealth 2016 Dec;13(4):796-807.
      doi: 10.1007/s10393-016-1176-ypubmed: 27709311google scholar: lookup
    45. Stilianakis NI, Syrris V, Petroliagkis T, Pärt P, Gewehr S, Kalaitzopoulou S, Mourelatos S, Baka A, Pervanidou D, Vontas J, Hadjichristodoulou C. Identification of Climatic Factors Affecting the Epidemiology of Human West Nile Virus Infections in Northern Greece. PLoS One 2016;11(9):e0161510.
      doi: 10.1371/journal.pone.0161510pubmed: 27631082google scholar: lookup
    46. Chaskopoulou A, L'Ambert G, Petric D, Bellini R, Zgomba M, Groen TA, Marrama L, Bicout DJ. Ecology of West Nile virus across four European countries: review of weather profiles, vector population dynamics and vector control response. Parasit Vectors 2016 Sep 2;9(1):482.
      doi: 10.1186/s13071-016-1736-6pubmed: 27590848google scholar: lookup
    47. Pisani G, Cristiano K, Pupella S, Liumbruno GM. West Nile Virus in Europe and Safety of Blood Transfusion. Transfus Med Hemother 2016 May;43(3):158-67.
      doi: 10.1159/000446219pubmed: 27403087google scholar: lookup
    48. Marini G, Poletti P, Giacobini M, Pugliese A, Merler S, Rosà R. The Role of Climatic and Density Dependent Factors in Shaping Mosquito Population Dynamics: The Case of Culex pipiens in Northwestern Italy. PLoS One 2016;11(4):e0154018.
      doi: 10.1371/journal.pone.0154018pubmed: 27105065google scholar: lookup
    49. Mweene-Ndumba I, Siziya S, Monze M, Mazaba ML, Masaninga F, Songolo P, Mwaba P, Babaniyi OA. Seroprevalence of West Nile Virus specific IgG and IgM antibodies in North-Western and Western provinces of Zambia. Afr Health Sci 2015 Sep;15(3):803-9.
      doi: 10.4314/ahs.v15i3.14pubmed: 26957968google scholar: lookup
    50. Szentpáli-Gavallér K, Lim SM, Dencső L, Bányai K, Koraka P, Osterhaus AD, Martina BE, Bakonyi T, Bálint Á. In Vitro and in Vivo Evaluation of Mutations in the NS Region of Lineage 2 West Nile Virus Associated with Neuroinvasiveness in a Mammalian Model. Viruses 2016 Feb 19;8(2).
      doi: 10.3390/v8020049pubmed: 26907325google scholar: lookup
    51. Ferraguti M, LA Puente JM, Soriguer R, Llorente F, Jiménez-Clavero MÁ, Figuerola J. West Nile virus-neutralizing antibodies in wild birds from southern Spain. Epidemiol Infect 2016 Jul;144(9):1907-11.
      doi: 10.1017/S0950268816000133pubmed: 26846720google scholar: lookup
    52. Dridi M, Van Den Berg T, Lecollinet S, Lambrecht B. Evaluation of the pathogenicity of West Nile virus (WNV) lineage 2 strains in a SPF chicken model of infection: NS3-249Pro mutation is neither sufficient nor necessary for conferring virulence. Vet Res 2015 Oct 30;46:130.
      doi: 10.1186/s13567-015-0257-1pubmed: 26518144google scholar: lookup
    53. Fortuna C, Remoli ME, Di Luca M, Severini F, Toma L, Benedetti E, Bucci P, Montarsi F, Minelli G, Boccolini D, Romi R, Ciufolini MG. Experimental studies on comparison of the vector competence of four Italian Culex pipiens populations for West Nile virus. Parasit Vectors 2015 Sep 17;8:463.
      doi: 10.1186/s13071-015-1067-zpubmed: 26383834google scholar: lookup
    54. Ravagnan S, Montarsi F, Cazzin S, Porcellato E, Russo F, Palei M, Monne I, Savini G, Marangon S, Barzon L, Capelli G. First report outside Eastern Europe of West Nile virus lineage 2 related to the Volgograd 2007 strain, northeastern Italy, 2014. Parasit Vectors 2015 Aug 13;8:418.
      doi: 10.1186/s13071-015-1031-ypubmed: 26265490google scholar: lookup
    55. Chaintoutis SC, Diakakis N, Papanastassopoulou M, Banos G, Dovas CI. Evaluation of Cross-Protection of a Lineage 1 West Nile Virus Inactivated Vaccine against Natural Infections from a Virulent Lineage 2 Strain in Horses, under Field Conditions. Clin Vaccine Immunol 2015 Sep;22(9):1040-9.
      doi: 10.1128/CVI.00302-15pubmed: 26178384google scholar: lookup
    56. Khoshdel-Nezamiha F, Vatandoost H, Azari-Hamidian S, Bavani MM, Dabiri F, Entezar-Mahdi R, Chavshin AR. Fauna and Larval Habitats of Mosquitoes (Diptera: Culicidae) of West Azerbaijan Province, Northwestern Iran. J Arthropod Borne Dis 2014 Dec;8(2):163-73.
      pubmed: 26114130
    57. Rizzoli A, Bolzoni L, Chadwick EA, Capelli G, Montarsi F, Grisenti M, de la Puente JM, Muñoz J, Figuerola J, Soriguer R, Anfora G, Di Luca M, Rosà R. Understanding West Nile virus ecology in Europe: Culex pipiens host feeding preference in a hotspot of virus emergence. Parasit Vectors 2015 Apr 9;8:213.
      doi: 10.1186/s13071-015-0831-4pubmed: 25888754google scholar: lookup
    58. Chancey C, Grinev A, Volkova E, Rios M. The global ecology and epidemiology of West Nile virus. Biomed Res Int 2015;2015:376230.
      doi: 10.1155/2015/376230pubmed: 25866777google scholar: lookup
    59. Hernández-Triana LM, Jeffries CL, Mansfield KL, Carnell G, Fooks AR, Johnson N. Emergence of west nile virus lineage 2 in europe: a review on the introduction and spread of a mosquito-borne disease. Front Public Health 2014;2:271.
      doi: 10.3389/fpubh.2014.00271pubmed: 25538937google scholar: lookup
    60. Ding XX, Li XF, Deng YQ, Guo YH, Hao W, Che XY, Qin CF, Fu N. Development of a double antibody sandwich ELISA for West Nile virus detection using monoclonal antibodies against non-structural protein 1. PLoS One 2014;9(10):e108623.
      doi: 10.1371/journal.pone.0108623pubmed: 25303282google scholar: lookup
    61. Di Sabatino D, Bruno R, Sauro F, Danzetta ML, Cito F, Iannetti S, Narcisi V, De Massis F, Calistri P. Epidemiology of West Nile disease in Europe and in the Mediterranean Basin from 2009 to 2013. Biomed Res Int 2014;2014:907852.
      doi: 10.1155/2014/907852pubmed: 25302311google scholar: lookup
    62. Szentpáli-Gavallér K, Antal L, Tóth M, Kemenesi G, Soltész Z, Dán A, Erdélyi K, Bányai K, Bálint A, Jakab F, Bakonyi T. Monitoring of West Nile virus in mosquitoes between 2011-2012 in Hungary. Vector Borne Zoonotic Dis 2014 Sep;14(9):648-55.
      doi: 10.1089/vbz.2013.1549pubmed: 25229703google scholar: lookup
    63. Bellini R, Zeller H, Van Bortel W. A review of the vector management methods to prevent and control outbreaks of West Nile virus infection and the challenge for Europe. Parasit Vectors 2014 Jul 11;7:323.
      doi: 10.1186/1756-3305-7-323pubmed: 25015004google scholar: lookup
    64. Rosà R, Marini G, Bolzoni L, Neteler M, Metz M, Delucchi L, Chadwick EA, Balbo L, Mosca A, Giacobini M, Bertolotti L, Rizzoli A. Early warning of West Nile virus mosquito vector: climate and land use models successfully explain phenology and abundance of Culex pipiens mosquitoes in north-western Italy. Parasit Vectors 2014 Jun 12;7:269.
      doi: 10.1186/1756-3305-7-269pubmed: 24924622google scholar: lookup
    65. Danial-Farran N, Eghbaria S, Schwartz N, Kra-Oz Z, Bisharat N. Genetic variants associated with susceptibility of Ashkenazi Jews to West Nile virus infection. Epidemiol Infect 2015 Mar;143(4):857-63.
      doi: 10.1017/S0950268814001290pubmed: 24865988google scholar: lookup
    66. Gray TJ, Webb CE. A review of the epidemiological and clinical aspects of West Nile virus. Int J Gen Med 2014;7:193-203.
      doi: 10.2147/IJGM.S59902pubmed: 24748813google scholar: lookup
    67. Verstrepen BE, Fagrouch Z, van Heteren M, Buitendijk H, Haaksma T, Beenhakker N, Palù G, Richner JM, Diamond MS, Bogers WM, Barzon L, Chabierski S, Ulbert S, Kondova I, Verschoor EJ. Experimental infection of rhesus macaques and common marmosets with a European strain of West Nile virus. PLoS Negl Trop Dis 2014 Apr;8(4):e2797.
      doi: 10.1371/journal.pntd.0002797pubmed: 24743302google scholar: lookup
    68. Platonov AE, Tolpin VA, Gridneva KA, Titkov AV, Platonova OV, Kolyasnikova NM, Busani L, Rezza G. The incidence of West Nile disease in Russia in relation to climatic and environmental factors. Int J Environ Res Public Health 2014 Jan 23;11(2):1211-32.
      doi: 10.3390/ijerph110201211pubmed: 24464233google scholar: lookup
    69. Hagman K, Barboutis C, Ehrenborg C, Fransson T, Jaenson TG, Lindgren PE, Lundkvist A, Nyström F, Waldenström J, Salaneck E. On the potential roles of ticks and migrating birds in the ecology of West Nile virus. Infect Ecol Epidemiol 2014 Jan 15;4.
      doi: 10.3402/iee.v4.20943pubmed: 24455105google scholar: lookup
    70. Ashhurst TM, Vreden Cv, Munoz-Erazo L, Niewold P, Watabe K, Terry RL, Deffrasnes C, Getts DR, Cole King NJ. Antiviral macrophage responses in flavivirus encephalitis. Indian J Med Res 2013 Nov;138(5):632-47.
      pubmed: 24434318
    71. Myint KS, Kosasih H, Artika IM, Perkasa A, Puspita M, Ma'roef CN, Antonjaya U, Ledermann JP, Powers AM, Alisjahbana B. West Nile virus documented in Indonesia from acute febrile illness specimens. Am J Trop Med Hyg 2014 Feb;90(2):260-2.
      doi: 10.4269/ajtmh.13-0445pubmed: 24420775google scholar: lookup
    72. Donadieu E, Lowenski S, Servely JL, Laloy E, Lilin T, Nowotny N, Richardson J, Zientara S, Lecollinet S, Coulpier M. Comparison of the neuropathology induced by two West Nile virus strains. PLoS One 2013;8(12):e84473.
      doi: 10.1371/journal.pone.0084473pubmed: 24367664google scholar: lookup
    73. Marka A, Diamantidis A, Papa A, Valiakos G, Chaintoutis SC, Doukas D, Tserkezou P, Giannakopoulos A, Papaspyropoulos K, Patsoula E, Badieritakis E, Baka A, Tseroni M, Pervanidou D, Papadopoulos NT, Koliopoulos G, Tontis D, Dovas CI, Billinis C, Tsakris A, Kremastinou J, Hadjichristodoulou C, Vakalis N, Vassalou E, Zarzani S, Zounos A, Komata K, Balatsos G, Beleri S, Mpimpa A, Papavasilopoulos V, Rodis I, Spanakos G, Tegos N, Spyrou V, Dalabiras Z, Birtsas P, Athanasiou L, Papanastassopoulou M, Ioannou C, Athanasiou C, Gerofotis C, Papadopoulou E, Testa T, Tsakalidou O, Rachiotis G, Bitsolas N, Mamouris Z, Moutou K, Sarafidou T, Stamatis K, Sarri K, Tsiodras S, Georgakopoulou T, Detsis M, Mavrouli M, Stavropoulou A, Politi L, Mageira G, Christopoulou V, Diamantopoulou G, Spanakis N, Vrioni G, Piperaki ET, Mitsopoulou K, Kioulos I, Michaelakis A, Stathis I, Tselentis I, Psaroulaki A, Keramarou M, Chochlakis D, Photis Y, Konstantinou M, Manetos P, Tsobanoglou S, Mourelatos S, Antalis V, Pergantas P, Eleftheriou G. West Nile virus state of the art report of MALWEST Project. Int J Environ Res Public Health 2013 Dec 2;10(12):6534-610.
      doi: 10.3390/ijerph10126534pubmed: 24317379google scholar: lookup
    74. Donadieu E, Bahuon C, Lowenski S, Zientara S, Coulpier M, Lecollinet S. Differential virulence and pathogenesis of West Nile viruses. Viruses 2013 Nov 22;5(11):2856-80.
      doi: 10.3390/v5112856pubmed: 24284878google scholar: lookup
    75. Barzon L, Pacenti M, Franchin E, Pagni S, Lavezzo E, Squarzon L, Martello T, Russo F, Nicoletti L, Rezza G, Castilletti C, Capobianchi MR, Salcuni P, Cattai M, Cusinato R, Palù G. Large human outbreak of West Nile virus infection in north-eastern Italy in 2012. Viruses 2013 Nov 22;5(11):2825-39.
      doi: 10.3390/v5112825pubmed: 24284876google scholar: lookup
    76. Ozdenerol E, Taff GN, Akkus C. Exploring the spatio-temporal dynamics of reservoir hosts, vectors, and human hosts of West Nile virus: a review of the recent literature. Int J Environ Res Public Health 2013 Oct 25;10(11):5399-432.
      doi: 10.3390/ijerph10115399pubmed: 24284356google scholar: lookup
    77. Martín-Acebes MA, Saiz JC. West Nile virus: A re-emerging pathogen revisited. World J Virol 2012 Apr 12;1(2):51-70.
      doi: 10.5501/wjv.v1.i2.51pubmed: 24175211google scholar: lookup
    78. Engler O, Savini G, Papa A, Figuerola J, Groschup MH, Kampen H, Medlock J, Vaux A, Wilson AJ, Werner D, Jöst H, Goffredo M, Capelli G, Federici V, Tonolla M, Patocchi N, Flacio E, Portmann J, Rossi-Pedruzzi A, Mourelatos S, Ruiz S, Vázquez A, Calzolari M, Bonilauri P, Dottori M, Schaffner F, Mathis A, Johnson N. European surveillance for West Nile virus in mosquito populations. Int J Environ Res Public Health 2013 Oct 11;10(10):4869-95.
      doi: 10.3390/ijerph10104869pubmed: 24157510google scholar: lookup
    79. Grisenti M, Arnoldi D, Rizzolli F, Giacobini M, Bertolotti L, Rizzoli A. Lack of identification of Flaviviruses in oral and cloacal swabs from long- and short-distance migratory birds in Trentino-Alto Adige (North-eastern Italy). Virol J 2013 Oct 11;10:306.
      doi: 10.1186/1743-422X-10-306pubmed: 24119320google scholar: lookup
    80. Barzon L, Pacenti M, Franchin E, Squarzon L, Lavezzo E, Cattai M, Cusinato R, Palù G. The complex epidemiological scenario of West Nile virus in Italy. Int J Environ Res Public Health 2013 Sep 30;10(10):4669-89.
      doi: 10.3390/ijerph10104669pubmed: 24084676google scholar: lookup
    81. Brandler S, Tangy F. Vaccines in development against West Nile virus. Viruses 2013 Sep 30;5(10):2384-409.
      doi: 10.3390/v5102384pubmed: 24084235google scholar: lookup
    82. Barzon L, Papa A, Pacenti M, Franchin E, Lavezzo E, Squarzon L, Masi G, Martello T, Testa T, Cusinato R, Palù G. Genome sequencing of West Nile Virus from human cases in Greece, 2012. Viruses 2013 Sep 24;5(9):2311-9.
      doi: 10.3390/v5092311pubmed: 24064795google scholar: lookup
    83. Iyer AV, Kousoulas KG. A review of vaccine approaches for West Nile virus. Int J Environ Res Public Health 2013 Sep 10;10(9):4200-23.
      doi: 10.3390/ijerph10094200pubmed: 24025396google scholar: lookup
    84. Reisen WK. Ecology of West Nile virus in North America. Viruses 2013 Sep 4;5(9):2079-105.
      doi: 10.3390/v5092079pubmed: 24008376google scholar: lookup
    85. Hubálek Z, Ludvíková E, Jahn P, Treml F, Rudolf I, Svobodová P, Šikutová S, Betášová L, Bíreš J, Mojžíš M, Tinák M, Boldižár M, Citsoňová G, Staššíková Z. West Nile Virus equine serosurvey in the Czech and Slovak republics. Vector Borne Zoonotic Dis 2013 Oct;13(10):733-8.
      doi: 10.1089/vbz.2012.1159pubmed: 23919605google scholar: lookup
    86. Cnops L, Papa A, Lagra F, Weyers P, Meersman K, Patsouros N, Van Esbroeck M. West Nile virus infection in Belgian traveler returning from Greece. Emerg Infect Dis 2013 Apr;19(4):684-5.
      doi: 10.3201/eid1904.121594pubmed: 23762912google scholar: lookup
    87. Gamino V, Höfle U. Pathology and tissue tropism of natural West Nile virus infection in birds: a review. Vet Res 2013 Jun 3;44(1):39.
      doi: 10.1186/1297-9716-44-39pubmed: 23731695google scholar: lookup
    88. Gomes B, Sousa CA, Vicente JL, Pinho L, Calderón I, Arez E, Almeida AP, Donnelly MJ, Pinto J. Feeding patterns of molestus and pipiens forms of Culex pipiens (Diptera: Culicidae) in a region of high hybridization. Parasit Vectors 2013 Apr 11;6:93.
      doi: 10.1186/1756-3305-6-93pubmed: 23578139google scholar: lookup
    89. Yazici Z, Albayrak H, Ozan E, Gumusova S. The first investigation of west nile virus in horses using real time rt-PCR in middle black sea region in Turkey. J Arthropod Borne Dis 2012 Dec;6(2):151-5.
      pubmed: 23378973
    90. Bernard S, Mailles A, Stahl JP. Epidemiology of infectious encephalitis, differences between a prospective study and hospital discharge data. Epidemiol Infect 2013 Nov;141(11):2256-68.
      doi: 10.1017/S0950268812002518pubmed: 23168268google scholar: lookup
    91. Berke O, Waller L. On the effect of diagnostic misclassification bias on the observed spatial pattern in regional count data--a case study using West Nile virus mortality data from Ontario, 2005. Spat Spatiotemporal Epidemiol 2010 Jul;1(2-3):117-22.
      doi: 10.1016/j.sste.2010.03.004pubmed: 22749468google scholar: lookup
    92. Jiménez-Clavero MÁ. Animal viral diseases and global change: bluetongue and West Nile fever as paradigms. Front Genet 2012;3:105.
      doi: 10.3389/fgene.2012.00105pubmed: 22707955google scholar: lookup
    93. Clark DC, Brault AC, Hunsperger E. The contribution of rodent models to the pathological assessment of flaviviral infections of the central nervous system. Arch Virol 2012 Aug;157(8):1423-40.
      doi: 10.1007/s00705-012-1337-4pubmed: 22592957google scholar: lookup
    94. Freitas FB, Novo MT, Esteves A, de Almeida AP. Species Composition and WNV Screening of Mosquitoes from Lagoons in a Wetland Area of the Algarve, Portugal. Front Physiol 2011;2:122.
      doi: 10.3389/fphys.2011.00122pubmed: 22347862google scholar: lookup
    95. Pesko KN, Ebel GD. West Nile virus population genetics and evolution. Infect Genet Evol 2012 Mar;12(2):181-90.
      doi: 10.1016/j.meegid.2011.11.014pubmed: 22226703google scholar: lookup
    96. Johnson N, Voller K, Phipps LP, Mansfield K, Fooks AR. Rapid molecular detection methods for arboviruses of livestock of importance to northern Europe. J Biomed Biotechnol 2012;2012:719402.
      doi: 10.1155/2012/719402pubmed: 22219660google scholar: lookup
    97. Bisanzio D, Giacobini M, Bertolotti L, Mosca A, Balbo L, Kitron U, Vazquez-Prokopec GM. Spatio-temporal patterns of distribution of West Nile virus vectors in eastern Piedmont Region, Italy. Parasit Vectors 2011 Dec 9;4:230.
      doi: 10.1186/1756-3305-4-230pubmed: 22152822google scholar: lookup
    98. Sonnleitner ST, Simeoni J, Schmutzhard E, Niedrig M, Ploner F, Schennach H, Dierich MP, Walder G. Absence of indigenous specific West Nile virus antibodies in Tyrolean blood donors. Eur J Clin Microbiol Infect Dis 2012 Jan;31(1):77-81.
      doi: 10.1007/s10096-011-1279-xpubmed: 21556676google scholar: lookup
    99. Rossini G, Carletti F, Bordi L, Cavrini F, Gaibani P, Landini MP, Pierro A, Capobianchi MR, Di Caro A, Sambri V. Phylogenetic analysis of West Nile virus isolates, Italy, 2008-2009. Emerg Infect Dis 2011 May;17(5):903-6.
      doi: 10.3201/eid1705.101569pubmed: 21529408google scholar: lookup
    100. Sotelo E, Gutierrez-Guzmán AV, del Amo J, Llorente F, El-Harrak M, Pérez-Ramírez E, Blanco JM, Höfle U, Jiménez-Clavero MA. Pathogenicity of two recent Western Mediterranean West Nile virus isolates in a wild bird species indigenous to Southern Europe: the red-legged partridge. Vet Res 2011 Jan 18;42(1):11.
      doi: 10.1186/1297-9716-42-11pubmed: 21314967google scholar: lookup
    101. Yeh JY, Lee JH, Seo HJ, Park JY, Moon JS, Cho IS, Choi IS, Park SY, Song CS, Lee JB. Simultaneous detection of Rift Valley Fever, bluetongue, rinderpest, and Peste des petits ruminants viruses by a single-tube multiplex reverse transcriptase-PCR assay using a dual-priming oligonucleotide system. J Clin Microbiol 2011 Apr;49(4):1389-94.
      doi: 10.1128/JCM.00710-10pubmed: 21307219google scholar: lookup
    102. Murray KO, Mertens E, Despres P. West Nile virus and its emergence in the United States of America. Vet Res 2010 Nov-Dec;41(6):67.
      doi: 10.1051/vetres/2010039pubmed: 21188801google scholar: lookup
    103. Yeh JY, Lee JH, Seo HJ, Park JY, Moon JS, Cho IS, Lee JB, Park SY, Song CS, Choi IS. Fast duplex one-step reverse transcriptase PCR for rapid differential detection of West Nile and Japanese encephalitis viruses. J Clin Microbiol 2010 Nov;48(11):4010-4.
      doi: 10.1128/JCM.00582-10pubmed: 20844215google scholar: lookup
    104. Toty C, Barré H, Le Goff G, Larget-Thiéry I, Rahola N, Couret D, Fontenille D. Malaria risk in Corsica, former hot spot of malaria in France. Malar J 2010 Aug 12;9:231.
      doi: 10.1186/1475-2875-9-231pubmed: 20704707google scholar: lookup
    105. Monini M, Falcone E, Busani L, Romi R, Ruggeri FM. West nile virus: characteristics of an african virus adapting to the third millennium world. Open Virol J 2010 Apr 22;4:42-51.
      doi: 10.2174/1874357901004020042pubmed: 20517488google scholar: lookup
    106. Durand B, Balança G, Baldet T, Chevalier V. A metapopulation model to simulate West Nile virus circulation in Western Africa, Southern Europe and the Mediterranean basin. Vet Res 2010 May-Jun;41(3):32.
      doi: 10.1051/vetres/2010004pubmed: 20167194google scholar: lookup
    107. Figuerola J, Baouab RE, Soriguer R, Fassi-Fihri O, Llorente F, Jímenez-Clavero MA. West Nile virus antibodies in wild birds, Morocco, 2008. Emerg Infect Dis 2009 Oct;15(10):1651-3.
      doi: 10.3201/eid1510.090340pubmed: 19861065google scholar: lookup
    108. Russo A, Farina E, Nicoletti L, Nemni R. Selective involvement of temporal regions in a case of flavivirus encephalitis. Neurol Sci 2009 Oct;30(5):413-5.
      doi: 10.1007/s10072-009-0114-ypubmed: 19590822google scholar: lookup
    109. Siirin MT, Travassos da Rosa AP, Newman P, Weeks-Levy C, Coller BA, Xiao SY, Lieberman MM, Watts DM. Evaluation of the efficacy of a recombinant subunit West Nile vaccine in Syrian golden hamsters. Am J Trop Med Hyg 2008 Dec;79(6):955-62.
      pubmed: 19052311
    110. Bouden M, Moulin B, Gosselin P. The geosimulation of West Nile virus propagation: a multi-agent and climate sensitive tool for risk management in public health. Int J Health Geogr 2008 Jul 7;7:35.
      doi: 10.1186/1476-072X-7-35pubmed: 18606008google scholar: lookup
    111. Monge Maillo B, López-Vélez R, Norman F, de Ory F, Sanchez-Seco MP, Giovanni Fedele C. Importation of West Nile virus infection from Nicaragua to Spain. Emerg Infect Dis 2008 Jul;14(7):1171-3.
      doi: 10.3201/eid1407.071496pubmed: 18598656google scholar: lookup
    112. Figuerola J, Soriguer R, Rojo G, Gómez Tejedor C, Jimenez-Clavero MA. Seroconversion in wild birds and local circulation of West Nile virus, Spain. Emerg Infect Dis 2007 Dec;13(12):1915-7.
      doi: 10.3201/eid1312.070343pubmed: 18258046google scholar: lookup
    113. Martín-Dávila P, Fortún J, López-Vélez R, Norman F, Montes de Oca M, Zamarrón P, González MI, Moreno A, Pumarola T, Garrido G, Candela A, Moreno S. Transmission of tropical and geographically restricted infections during solid-organ transplantation. Clin Microbiol Rev 2008 Jan;21(1):60-96.
      doi: 10.1128/CMR.00021-07pubmed: 18202437google scholar: lookup
    114. Tsiodras S, Kelesidis T, Kelesidis I, Bauchinger U, Falagas ME. Human infections associated with wild birds. J Infect 2008 Feb;56(2):83-98.
      doi: 10.1016/j.jinf.2007.11.001pubmed: 18096237google scholar: lookup
    115. El Adlouni S, Beaulieu C, Ouarda TB, Gosselin PL, Saint-Hilaire A. Effects of climate on West Nile Virus transmission risk used for public health decision-making in Q. Int J Health Geogr 2007 Sep 20;6:40.
      doi: 10.1186/1476-072X-6-40pubmed: 17883862google scholar: lookup
    116. Keller BC, Johnson CL, Erickson AK, Gale M Jr. Innate immune evasion by hepatitis C virus and West Nile virus. Cytokine Growth Factor Rev 2007 Oct-Dec;18(5-6):535-44.
      doi: 10.1016/j.cytogfr.2007.06.006pubmed: 17702639google scholar: lookup
    117. Niedrig M, Donoso Mantke O, Altmann D, Zeller H. First international diagnostic accuracy study for the serological detection of West Nile virus infection. BMC Infect Dis 2007 Jul 3;7:72.
      doi: 10.1186/1471-2334-7-72pubmed: 17608925google scholar: lookup
    118. Beroll H, Berke O, Wilson J, Barker IK. Investigating the spatial risk distribution of West Nile virus disease in birds and humans in southern Ontario from 2002 to 2005. Popul Health Metr 2007 May 1;5:3.
      doi: 10.1186/1478-7954-5-3pubmed: 17472753google scholar: lookup
    119. Vorou RM, Papavassiliou VG, Tsiodras S. Emerging zoonoses and vector-borne infections affecting humans in Europe. Epidemiol Infect 2007 Nov;135(8):1231-47.
      doi: 10.1017/S0950268807008527pubmed: 17445320google scholar: lookup
    120. Cabre O, Grandadam M, Marié JL, Gravier P, Prangé A, Santinelli Y, Rous V, Bourry O, Durand JP, Tolou H, Davoust B. West Nile Virus in horses, sub-Saharan Africa. Emerg Infect Dis 2006 Dec;12(12):1958-60.
      doi: 10.3201/eid1212.060042pubmed: 17326952google scholar: lookup
    121. Niedrig M, Linke S, Zeller H, Drosten C. First international proficiency study on West Nile virus molecular detection. Clin Chem 2006 Oct;52(10):1851-4.
      doi: 10.1373/clinchem.2005.064451pubmed: 16887901google scholar: lookup
    122. Bakonyi T, Ivanics E, Erdélyi K, Ursu K, Ferenczi E, Weissenböck H, Nowotny N. Lineage 1 and 2 strains of encephalitic West Nile virus, central Europe. Emerg Infect Dis 2006 Apr;12(4):618-23.
      doi: 10.3201/eid1204.051379pubmed: 16704810google scholar: lookup
    123. Hayes EB, Komar N, Nasci RS, Montgomery SP, O'Leary DR, Campbell GL. Epidemiology and transmission dynamics of West Nile virus disease. Emerg Infect Dis 2005 Aug;11(8):1167-73.
      doi: 10.3201/eid1108.050289apubmed: 16102302google scholar: lookup
    124. Schuffenecker I, Peyrefitte CN, el Harrak M, Murri S, Leblond A, Zeller HG. West Nile virus in Morocco, 2003. Emerg Infect Dis 2005 Feb;11(2):306-9.
      doi: 10.3201/eid1102.040817pubmed: 15752452google scholar: lookup
    125. Bakonyi T, Hubálek Z, Rudolf I, Nowotny N. Novel flavivirus or new lineage of West Nile virus, central Europe. Emerg Infect Dis 2005 Feb;11(2):225-31.
      doi: 10.3201/eid1102.041028pubmed: 15752439google scholar: lookup
    126. Ozharovskaia TA, Zubkova OV, Korobova EV, Dolzhikova IV, Zrelkin DI, Popova O, Goldovskaya PP, Kovyrshina AV, Korobkova AI, Favorskaya IA, Vavilova IV, Grousova DM, Zorkov ID, Iliukhina AA, Ermolova IA, Tukhvatulin AI, Shcherbinin DN, Ermolova EI, Kunda MS, Ryzhova NN, Voronina OL, Semikhin AS, Shcheblyakov DV, Logunov DY, Gintsburg AL. Adenoviral Vectors Expressing Optimized preM/E Genes of WNV Deliver Long-Term Protection Against Lethal West Nile Virus Challenge. Vaccines (Basel) 2025 Nov 21;13(12).
      doi: 10.3390/vaccines13121177pubmed: 41441644google scholar: lookup
    127. Fesce E, Marini G, Rosà R, Lelli D, Cerioli MP, Chiari M, Farioli M, Ferrari N. Are we doing our best to contain the spread of West Nile virus? Evaluating intervention efficacy through mathematical modelling. Parasit Vectors 2025 Dec 5;18(1):499.
      doi: 10.1186/s13071-025-07128-9pubmed: 41351019google scholar: lookup
    128. Gutiérrez-López R, Fernández-Delgado R, Aguilera-Sepúlveda P, Dafouz-Bustos D, Jiménez-Clavero MÁ, Llorente F. Spanish West Nile virus isolates of lineages 1 and 2 elicit different patterns of infection in red-legged partridges. J Gen Virol 2025 Dec;106(12).
      doi: 10.1099/jgv.0.002186pubmed: 41342525google scholar: lookup
    129. Nett RJ, Brault AC, Lambert AJ, Agnihothram S, Barrett ADT, Barzon L, Clements DE, Durbin A, Kretschmer M, Monath TP, Mura M, Pierson TC, Prutzman K, Slifka MK, Suthar MS, Whitehead SS, Staples JE. Summary of human West Nile virus vaccine meeting, 2024: Investigating barriers to development. Vaccine 2025 Dec 5;68:127938.
      doi: 10.1016/j.vaccine.2025.127938pubmed: 41197444google scholar: lookup
    130. Roßbacher L, Taschler S, Cecchettin E, Popovitsch A, Aberle SW, Aberle JH, Medits-Weiss I, Stiasny K. Differentiation of West Nile and Usutu Virus Infections by Antibodies Directed to the Non-Structural Protein 1. Viruses 2025 Oct 10;17(10).
      doi: 10.3390/v17101357pubmed: 41157627google scholar: lookup
    131. Nabti I, Chahed S. Ecological niche and risk modeling of West Nile virus using environmental and biological thresholds. Arch Microbiol 2025 Oct 6;207(11):289.
      doi: 10.1007/s00203-025-04488-9pubmed: 41051436google scholar: lookup
    132. Bruce RC, Abbott AJ, Jones BP, Gardner BL, Gonzalez E, Ionescu AM, Jagdev M, Jenkins A, Santos M, Seilern-Macpherson K, Hanmer HJ, Robinson RA, Vaux AG, Johnson N, Cunningham AA, Lawson B, Medlock JM, Folly AJ. Detection of West Nile virus via retrospective mosquito arbovirus surveillance, United Kingdom, 2025. Euro Surveill 2025 Jul;30(28).
      doi: 10.2807/1560-7917.ES.2025.30.28.2500401pubmed: 40682455google scholar: lookup
    133. Sohier C, Breman FC, Vervaeke M, De Regge N. West Nile Virus Monitoring in Flanders (Belgium) During 2022-2023 Reveals Endemic Usutu Virus Circulation in Birds. Transbound Emerg Dis 2024;2024:4146156.
      doi: 10.1155/tbed/4146156pubmed: 40303116google scholar: lookup
    134. Lara M, Casimiro-Soriguer CS, Pedrosa-Corral I, Gómez-Camarasa C, Lorusso N, Navarro-Marí JM, Dopazo J, Perez-Florido J, Sanbonmatsu-Gámez S. First autochthonous transmission of West Nile virus (WNV) lineage 2 to humans in Spain. One Health 2025 Jun;20:101036.
      doi: 10.1016/j.onehlt.2025.101036pubmed: 40276693google scholar: lookup
    135. Ouni A, Aounallah H, Rebai WK, Llorente F, Chendoul W, Hammami W, Rhim A, Jiménez-Clavero MÁ, Pérez-Ramírez E, Bouattour A, M'Ghirbi Y. The Role of Ruminants as Sentinel Animals in the Circulation of the West Nile Virus in Tunisia. Pathogens 2025 Mar 8;14(3).
      doi: 10.3390/pathogens14030267pubmed: 40137752google scholar: lookup
    136. Rodríguez-Valencia V, Olive MM, Le Goff G, Faisse M, Bourel M, L'Ambert G, Vollot B, Tolsá-García MJ, Paupy C, Roiz D. Host-feeding preferences of Culex pipiens and its potential significance for flavivirus transmission in the Camargue, France. Med Vet Entomol 2025 Sep;39(3):614-625.
      doi: 10.1111/mve.12802pubmed: 40118784google scholar: lookup
    137. Rodriguez-Valencia V, Olive MM, Le Goff G, Faisse M, Paupy C, Roiz D. Lower Bird Evenness and Diversity Are Associated With Higher Usutu Prevalence in Culex pipiens Mosquitoes. Zoonoses Public Health 2025 Jun;72(4):359-368.
      doi: 10.1111/zph.13213pubmed: 39963005google scholar: lookup
    138. Sabadi D, Bodulić K, Savić V, Vlahović Vlašić N, Bogdanić M, Perić L, Tabain I, Lišnjić D, Duvnjak M, Židovec-Lepej S, Grubišić B, Rubil I, Barbić L, Švitek L, Stevanović V, Smajić P, Berišić B, Zlosa M, Rončević I, Vilibić-Čavlek T. Clinical Characteristics, Laboratory Parameters, and Molecular Epidemiology of Neuroinvasive Flavivirus Infections in a Hotspot Region of Eastern Croatia. Pathogens 2025 Jan 14;14(1).
      doi: 10.3390/pathogens14010069pubmed: 39861030google scholar: lookup
    139. D'Arena G, Palladino C, Bosco M, Gambardella M. West Nile Virus Encephalitis in a Patient with Chronic Lymphocytic Leukemia. Mediterr J Hematol Infect Dis 2025;17(1):e2025010.
      doi: 10.4084/MJHID.2025.010pubmed: 39830796google scholar: lookup
    140. Vorovitch MF, Tuchynskaya KK, Kruglov YA, Peunkov NS, Mostipanova GF, Kholodilov IS, Ivanova AL, Fedina MP, Gmyl LV, Morozkin ES, Roev GV, Karan LS, Karganova GG. An Inactivated West Nile Virus Vaccine Candidate Based on the Lineage 2 Strain. Vaccines (Basel) 2024 Dec 12;12(12).
      doi: 10.3390/vaccines12121398pubmed: 39772058google scholar: lookup
    141. Vignjević G, Bušić N, Turić N, Varga Z, Zana B, Ábrahám Á, Kurucz K, Vrućina I, Merdić E. First Detection of West Nile Virus Lineage 2 in Culex pipiens Vectors in Croatia. Pathogens 2024 Dec 21;13(12).
      doi: 10.3390/pathogens13121131pubmed: 39770390google scholar: lookup
    142. Hamel R, Narpon Q, Serrato-Pomar I, Gauliard C, Berthomieu A, Wichit S, Missé D, Sofonea MT, Pompon J. West Nile virus can be transmitted within mosquito populations through infectious mosquito excreta. iScience 2024 Nov 15;27(11):111099.
      doi: 10.1016/j.isci.2024.111099pubmed: 39473977google scholar: lookup
    143. Lani R, Thariq IM, Suhaimi NS, Hassandarvish P, Abu Bakar S. From defense to offense: Modulating toll-like receptors to combat arbovirus infections. Hum Vaccin Immunother 2024 Dec 31;20(1):2306675.
      doi: 10.1080/21645515.2024.2306675pubmed: 38263674google scholar: lookup
    144. Ben-Mostafa KK, Savini G, Di Gennaro A, Teodori L, Leone A, Monaco F, Alaoqib MMA, Rayes AA, Dayhum A, Eldaghayes I. Evidence of West Nile Virus Circulation in Horses and Dogs in Libya. Pathogens 2023 Dec 31;13(1).
      doi: 10.3390/pathogens13010041pubmed: 38251348google scholar: lookup
    145. Cazzin S, Liechti N, Jandrasits D, Flacio E, Beuret C, Engler O, Guidi V. First Detection of West Nile Virus Lineage 2 in Mosquitoes in Switzerland, 2022. Pathogens 2023 Dec 7;12(12).
      doi: 10.3390/pathogens12121424pubmed: 38133307google scholar: lookup
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