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Comparative immunology, microbiology and infectious diseases2017; 53; 45-49; doi: 10.1016/j.cimid.2017.06.006

West Nile virus infection in horses, Indian ocean.

Abstract: The circulation of West Nile virus (WNV) in horses was investigated in the Southwest Indian ocean. In 2010, blood samples were collected from a total of 303 horses originating from Madagascar, Mauritius, Reunion and the Seychelles and tested for WNV-specific antibodies. An overall seroprevalence of 27.39% was detected in the Indian Ocean with the highest WNV antibody prevalence of 46.22% (95% CI: [37.4-55.2%]) in Madagascar. The age and origin of the horses were found to be associated with the WNV infection risk. This paper presents the first seroprevalence study investigating WN fever in horses in the Southwest Indian Ocean area and indicates a potential risk of infection for humans and animals. In order to gain a better understanding of WN transmission cycles, WNV surveillance needs to be implemented in each of the countries.
Publication Date: 2017-07-04 PubMed ID: 28750867DOI: 10.1016/j.cimid.2017.06.006Google Scholar: Lookup
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Summary

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This study investigates the occurrence of West Nile Virus (WNV) among horses in the southwest Indian Ocean. The research revealed a 27.39% overrall seroprevalence rate, suggesting a potential risk of human and animal infection in the area.

Research Context and Method

The study aimed to examine the prevalence of West Nile virus (WNV) infection in horses located in the southwest Indian Ocean. The region was of interest because of the lack of previous epidemiological data regarding West Nile virus in horses from this area. In 2010, the researchers gathered blood samples from 303 horses from different islands, including Madagascar, Mauritius, Reunion, and Seychelles.

  • The collected samples were tested for the presence of WNV-specific antibodies. These antibodies are the immune system’s response to infection with the virus, and their presence suggests that the horse has been infected at some point.

Results of the Study

After testing the samples, the authors found an overall seroprevalence of WNV infection of 27.39% across all the sampled horses. This implies that nearly 27 in 100 horses in these regions have encountered the virus.

  • Of the tested locations, Madagascar stood out with the highest WNV antibody prevalence, at 46.22%, suggesting that almost half of the horses on the island have been exposed to the virus.
  • The study also established an association between the age and geographic location (origin) of the horses and the likelihood of WNV infection.

Conclusions and Implications

This research signifies the first seroprevalence study investigating West Nile fever in horses in the southwest Indian Ocean region. The findings indicate a potential risk of WNV infection for both humans and animals in these areas, particularly in Madagascar.

  • The results prompt the need for WNV surveillance to be implemented in each of the countries involved. Such monitoring would help in understanding the transmission patterns of the virus, which could be valuable in predicting and managing potential outbreaks, thereby protecting human and animal health.

Cite This Article

APA
Cardinale E, Bernard C, Lecollinet S, Rakotoharinome VM, Ravaomanana J, Roger M, Olive MM, Meenowa D, Jaumally MR, Melanie J, Héraud JM, Zientara S, Cêtre-Sossah C. (2017). West Nile virus infection in horses, Indian ocean. Comp Immunol Microbiol Infect Dis, 53, 45-49. https://doi.org/10.1016/j.cimid.2017.06.006

Publication

ISSN: 1878-1667
NlmUniqueID: 7808924
Country: England
Language: English
Volume: 53
Pages: 45-49
PII: S0147-9571(17)30053-X

Researcher Affiliations

Cardinale, E
  • CIRAD, UMR 117 ASTRE, Cyroi Platform, F-97490 Sainte Clotilde, La Réunion, France; INRA, UMR 1309 ASTRE, F-34598 Montpellier, France. Electronic address: eric.cardinale@cirad.fr.
Bernard, C
  • CIRAD, UMR 117 ASTRE, Cyroi Platform, F-97490 Sainte Clotilde, La Réunion, France; INRA, UMR 1309 ASTRE, F-34598 Montpellier, France.
Lecollinet, S
  • UMR 1161 (ANSES/INRA/ENVA), EU-RL on Equine Diseases, F- 94701 Maisons-Alfort, France.
Rakotoharinome, V M
  • Ministère auprès de la Présidence en charge de l'Agriculture, de l'Elevage, Direction des Services Vétérinaires, Ampandrianomby, Antananarivo, Madagascar.
Ravaomanana, J
  • Centre National de la Recherche Appliquée au Développement Rural (Fofifa), Département de Recherches Zootechniques et Vétérinaires, Antananarivo, Madagascar.
Roger, M
  • CIRAD, UMR 117 ASTRE, Cyroi Platform, F-97490 Sainte Clotilde, La Réunion, France; INRA, UMR 1309 ASTRE, F-34598 Montpellier, France.
Olive, M M
  • CIRAD, UMR 117 ASTRE, Cyroi Platform, F-97490 Sainte Clotilde, La Réunion, France; INRA, UMR 1309 ASTRE, F-34598 Montpellier, France.
Meenowa, D
  • Ministère des Agro-Industries, Réduit, Mauritius.
Jaumally, M R
  • Ministère des Agro-Industries, Réduit, Mauritius.
Melanie, J
  • Ministère de l'Agriculture et des ressources marines, Victoria, Seychelles.
Héraud, J M
  • Institut Pasteur de Madagascar, Unité de Virologie, BP 1274, Antananarivo 101, Madagascar.
Zientara, S
  • UMR 1161 (ANSES/INRA/ENVA), EU-RL on Equine Diseases, F- 94701 Maisons-Alfort, France.
Cêtre-Sossah, C
  • CIRAD, UMR 117 ASTRE, Cyroi Platform, F-97490 Sainte Clotilde, La Réunion, France; INRA, UMR 1309 ASTRE, F-34598 Montpellier, France.

MeSH Terms

  • Animals
  • Antibodies, Viral / blood
  • Enzyme-Linked Immunosorbent Assay
  • Horse Diseases / epidemiology
  • Horse Diseases / immunology
  • Horse Diseases / virology
  • Horses
  • Humans
  • Indian Ocean / epidemiology
  • Neutralization Tests
  • Seroepidemiologic Studies
  • West Nile Fever / epidemiology
  • West Nile Fever / transmission
  • West Nile Fever / veterinary
  • West Nile Fever / virology
  • West Nile virus / immunology

Citations

This article has been cited 12 times.