[West Nile virus infections: overview and epidemiological update].
Abstract: West Nile virus, a flavivirus transmitted by mosquitoes, has been intensively studied since a few years because of epidemics/epizootics it has caused the last ten years, in particular around the Mediterranean basin and on the North-American continent. This virus mainly circulates in birds ; migrating bird species disseminate the virus while resident species could play a role in viral cycle amplification. A large number of mammal, amphibian and reptile species can also be infected. This virus can cause a lethal disease in humans and horses. For this reason, an active and/or passive surveillance is carried out in France and in United States at different steps of the transmission cycle : insects, birds, horses and humans. This surveillance is aimed at precociously detecting viral circulation and, if detected, take suitable information, prevention and fight measures. Furthermore, the description of new transmission routes of infection has led to precaution measures for blood and organ donations in the US and in a lesser extent, in France. As West Nile epidemiology is only partially known, most of epidemics remain unpredictable and difficult to control.
Publication Date: 2005-10-01 PubMed ID: 34679285DOI: 10.1684/vir.2011.2401Google Scholar: Lookup
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Summary
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This research article explores the rising threat of West Nile virus, a mosquito-borne disease primarily transmitted by birds, with studies focusing on its widespread epidemic in the Mediterranean and North American regions. The article goes on to discuss the virus’s impact on humans and horses and the surveillance measures implemented in France and United States, alongside precautionary steps in blood and organ donations.
Introduction and Background
- The article begins with an introduction to West Nile virus, a flavivirus transmitted primarily by mosquitoes. The interest in this virus has grown due to the widespread epidemics and epizootics it has caused, especially around the Mediterranean basin and North American continent in the last decade.
- The primary carriers of this virus are birds, with migrating bird species playing a significant role in spreading the virus and local bird populations possibly contributing to amplifying the viral cycle. The virus can also infect a wide range of mammals, amphibians, and reptiles.
Impact of the Virus
- This virus has a significant impact on human and horse populations, potentially causing lethal diseases. The severity of the disease has led to ongoing active and passive surveillance efforts, particularly in France and the United States, to monitor its spread and impact.
Surveillance Measures
- The surveillance methods involve monitoring at different stages of the transmission cycle, including insects, birds, horses, and humans. The aim is to detect the virus’s circulation early and, if necessary, implement appropriate information dissemination, prevention, and control measures.
Precautionary Steps
- Additional safety measures have been instituted due to the discovery of new routes of infection transmission. In particular, precautionary measures have been implemented in blood and organ donations in the US and, to a lesser degree, in France.
Current Challenges
- The paper notes that, given our incomplete understanding of the West Nile virus’s epidemiology, most epidemics remain unpredictable and challenging to control. This highlights the importance of continued study and observation of the virus.
Cite This Article
APA
Dauphin G, Zientara S.
(2005).
[West Nile virus infections: overview and epidemiological update].
Virologie (Montrouge), 9(5), 395-408.
https://doi.org/10.1684/vir.2011.2401 Publication
Researcher Affiliations
- Agence française de sécurité sanitaire des aliments, UMR 1161 de virologie (Inra/Afssa/Enva), 23 avenue du Général-de-Gaulle, 94703 Maisons-Alfort.
- Agence française de sécurité sanitaire des aliments, UMR 1161 de virologie (Inra/Afssa/Enva), 23 avenue du Général-de-Gaulle, 94703 Maisons-Alfort.
Citations
This article has been cited 1 times.- Martin MF, Nisole S. West Nile Virus Restriction in Mosquito and Human Cells: A Virus under Confinement. Vaccines (Basel) 2020 May 29;8(2).
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