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Veterinary journal (London, England : 1997)2009; 186(2); 192-196; doi: 10.1016/j.tvjl.2009.07.017

Whole blood selenium concentrations in endurance horses.

Abstract: Exercise causes an increase in the production of reactive oxygen species, which can result in oxidant/antioxidant disequilibrium. Deficiency of antioxidants can further alter this balance in favor of pro-oxidation. Selenium (Se) is one of many antioxidant catalysts, as a component of the glutathione peroxidase enzymes. Soils and forages vary widely in Se concentration and a deficient diet can lead to sub-clinical or clinical deficiency in horses. Endurance horses are prone to oxidative stress during long periods of aerobic exercise and their performance could be affected by Se status. This study investigated the blood Se concentration in a group of endurance horses (n=56) residing and competing in California, a state containing several regions that tend to produce Se-deficient forages. The rate of Se deficiency in this group of horses was low, with only one horse being slightly below the reference range. Higher blood Se concentrations were not associated with improved performance in terms of ride time. There was no significant difference in Se concentration between horses that completed the ride and those that were disqualified, although blood Se concentrations were significantly higher in horses that received oral Se supplementation. An increase in blood Se concentration was observed following exercise and this warrants further study.
Publication Date: 2009-08-19 PubMed ID: 19695911DOI: 10.1016/j.tvjl.2009.07.017Google Scholar: Lookup
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Summary

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The research article investigates the concentration of Selenium (Se), a known antioxidant catalyst, in the blood of endurance horses from California due to potential Se deficency from the region’s forage. The study found a low rate of Se deficiency, no concrete link between high Se concentration and improved performance, but noted increased Se concentration in horses after exercise.

Importance of Selenium in Endurance Horses

  • Exercise can lead to increased production of reactive oxygen species which, without a sufficient supply of antioxidants, can cause an imbalance favoring pro-oxidation.
  • Among antioxidants, Selenium (Se) plays a crucial role as it forms part of the glutathione peroxidase enzymes.
  • Endurance horses prone to oxidative stress due to prolonged aerobic exercise could have their performance impacted by their Se status.

Selenium Supply in the Diet

  • Soils and forages, which contribute to the diet of horses, vary widely in their Se concentration.
  • A Se-deficient diet can lead to sub-clinical or clinical deficiency in horses, which may impact overall health and performance.
  • The study focuses on a group of endurance horses from California, a region which tends to produce Se-deficient forages.

Findings of the Study

  • The rate of Se deficiency in the group of horses studied was relatively low, with only one horse slightly below the reference range, indicating that the Se intake via their diet was adequate for the most part.
  • There was no defined association between higher blood Se concentrations and improved performance in terms of ride time, indicating that having higher-than-required Se in the blood doesn’t necessarily improve performance.
  • No significant difference in Se concentration was observed between horses that completed the ride and those that were disqualified, possibly illustrating that Se levels do not directly affect the ability to complete a ride.
  • Horses that received oral Se supplementation had significantly higher blood Se concentrations, indicating that oral supplements can effectively elevate Se levels.

Post-Exercise Selenium Concentration Changes

  • An increase in blood Se concentration was observed following exercise, but the phenomenon’s implications need to be further studied to understand its effects on horse health and endurance.

Cite This Article

APA
Haggett E, Magdesian KG, Maas J, Puschner B, Higgins J, Fiack C. (2009). Whole blood selenium concentrations in endurance horses. Vet J, 186(2), 192-196. https://doi.org/10.1016/j.tvjl.2009.07.017

Publication

ISSN: 1532-2971
NlmUniqueID: 9706281
Country: England
Language: English
Volume: 186
Issue: 2
Pages: 192-196

Researcher Affiliations

Haggett, Emily
  • William R. Pritchard Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.
Magdesian, K Gary
    Maas, John
      Puschner, Birgit
        Higgins, Jamie
          Fiack, Ciara

            MeSH Terms

            • Animal Feed / analysis
            • Animal Nutritional Physiological Phenomena
            • Animals
            • California / epidemiology
            • Diet / veterinary
            • Dietary Supplements
            • Horse Diseases / blood
            • Horse Diseases / epidemiology
            • Horses / blood
            • Horses / physiology
            • Oxidative Stress
            • Physical Conditioning, Animal / physiology
            • Physical Endurance / physiology
            • Prevalence
            • Prospective Studies
            • Selenium / administration & dosage
            • Selenium / blood
            • Selenium / deficiency

            Citations

            This article has been cited 1 times.
            1. Kalashnikov V, Zajcev A, Atroshchenko M, Miroshnikov S, Frolov A, Zav'yalov O, Kalinkova L, Kalashnikova T. The content of essential and toxic elements in the hair of the mane of the trotter horses depending on their speed. Environ Sci Pollut Res Int 2018 Aug;25(22):21961-21967.
              doi: 10.1007/s11356-018-2334-2pubmed: 29797197google scholar: lookup