Bioactive materials.
Publisher:
Ke Ai Publishing
Frequency: Quarterly
Country: China
Language: English
Start Year:2016 -
ISSN:
2452-199X (Electronic)
2452-199X (Linking)
2452-199X (Linking)
Impact Factor
18.9
2022
| NLM ID: | 101685294 |
| (OCoLC): | 959653589 |
| LCCN: | 2017243133 |
| Classification: | W1 |
Development of novel gene carrier using modified nano hydroxyapatite derived from equine bone for osteogenic differentiation of dental pulp stem cells. Hydroxyapatite (HA) is a representative substance that induces bone regeneration. Our research team extracted nanohydroxyapatite (EH) from natural resources, especially equine bones, and developed it as a molecular biological tool. Polyethylenimine (PEI) was used to coat the EH to develop a gene carrier. To verify that PEI is well coated in the EH, we first observed the morphology and dispersity of PEI-coated EH (pEH) by electron microscopy. The pEH particles were well distributed, while only the EH particles were not distributed and aggregated. Then, the existence of nitrogen elements of PEI ...