BMC medical genomics.
Publisher:
BioMed Central
Country: England
Language: English
Author(s):
BioMed Central Ltd.
Start Year:2008 -
ISSN:
1755-8794 (Electronic)
1755-8794 (Linking)
1755-8794 (Linking)
Impact Factor
2.7
2022
| NLM ID: | 101319628 |
| (OCoLC): | 192139362 |
| LCCN: | 2008243213 |
Transcriptional profiling differences for articular cartilage and repair tissue in equine joint surface lesions. Full-thickness articular cartilage lesions that reach to the subchondral bone yet are restricted to the chondral compartment usually fill with a fibrocartilage-like repair tissue which is structurally and biomechanically compromised relative to normal articular cartilage. The objective of this study was to evaluate transcriptional differences between chondrocytes of normal articular cartilage and repair tissue cells four months post-microfracture. Methods: Bilateral one-cm2 full-thickness defects were made in the articular surface of both distal femurs of four adult horses followed by subchond...