Cell biology and toxicology.
Publisher:
Princeton Scientific Publishers,. [Cham] : Springer
Frequency: Six no. a year
Country: Switzerland
Language: English
Start Year:1984 -
ISSN:
0742-2091 (Print)
1573-6822 (Electronic)
0742-2091 (Linking)
1573-6822 (Electronic)
0742-2091 (Linking)
Impact Factor
6.1
2022
| NLM ID: | 8506639 |
| (DNLM): | SR0050364(s) |
| (OCoLC): | 12617538 |
| Coden: | CBTOE2 |
| LCCN: | 86641133 |
| Classification: | W1 CE128FH |
The effect of enrofloxacin on cell proliferation and proteoglycans in horse tendon cells. Fluoroquinolone antibiotics have been used widely in humans and domestic animals, including horses, because of their broad-spectrum bactericidal activity, and relative safety. The use of fluoroquinolones, however, is not without risk. Tendonitis and spontaneous tendon rupture have been reported in people during or following therapy with fluoroquinolones. We have studied the effects of enrofloxacin, a fluoroquinolone antibiotic used commonly in domestic animals, on tendon cell cultures established from equine superficial digital flexor tendons. Effects on cell proliferation and morphology were ...
Establishment and characterization of equine autonomic ganglion cell lines to enable direct testing of candidate toxins involved in equine dysautonomia (grass sickness). To enable direct testing of a range of potential toxins or pathogens that might be involved in grass sickness, equine thoracic sympathetic chain ganglion cell lines were established from primary cell cultures by retroviral-mediated transduction of the temperature-sensitive mutant of the establishment oncogene encoding SV40 large T antigen. Morphological and behavioral features, temperature dependence, and immunocytochemical characteristics of the cell lines were investigated. The majority of cells were noradrenergic neurons in which dopamine-beta-hydroxylase, the enzyme that catalyzes norepine...