Differentiation; research in biological diversity.
Publisher:
Macmillan Journals.. London : Elsevier
Frequency: Ten no. a year
Country: England
Language: English
Start Year:1973 -
ISSN:
0301-4681 (Print)
1432-0436 (Electronic)
0301-4681 (Linking)
1432-0436 (Electronic)
0301-4681 (Linking)
Impact Factor
2.9
2022
| NLM ID: | 0401650 |
| (OCoLC): | 02240102 |
| (DNLM): | D10460000(s) |
| Coden: | DFFNAW |
| LCCN: | 74648484 |
| Classification: | W1 DI531 |
Phospholipase A2 products predict the hematopoietic support capacity of horse serum. Horse serum is commonly used as an additive to support the maintenance of hematopoietic progenitor cells in culture. However, the wide variability in the performance of different lots calls for parallel testing of multiple batches over extended periods of culture. Identification of the serum components that determine hematopoietic support would therefore save considerable time and effort and would help to standardize culture procedures. We report here that the ability of horse serum to support the self-renewal of multipotent murine hematopoietic progenitor FDCP-Mix cells is correlated to the c...
Multilineage differentiation potential of equine blood-derived fibroblast-like cells. Tissue engineering (TE) has emerged as a promising new therapy for the treatment of damaged tissues and organs. Adult stem cells are considered as an attractive candidate cell type for cell-based TE. Mesenchymal stem cells (MSC) have been isolated from a variety of tissues and tested for differentiation into different cell lineages. While clinical trials still await the use of human MSC, horse tendon injuries are already being treated with autologous bone marrow-derived MSC. Given that the bone marrow is not an optimal source for MSC due to the painful and risk-containing sampling procedure, i...
Developmental regulation of class I major histocompatibility complex antigen expression by equine trophoblastic cells. Between days 36-38 of pregnancy equine trophoblastic cells of the chorionic girdle migrate and form endometrial cups. Just prior to invasion, the chorionic girdle cells express high levels of polymorphic, paternally inherited, major histocompatibility complex (MHC) class I antigens. Their descendents, the mature, invasive trophoblast cells of the endometrial cups, however, express low or undetectable levels of MHC class I antigens by day 44 of pregnancy. Experiments with MHC compatible pregnancies, the study of residual chorionic girdle cells that had failed to invade the endometrium and remai...