Omneity® Pellets
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Discov Immunol
Dendritic-cell diversity in equine blood revealed by single-cell transcriptomics. Detailed classification of equine dendritic cells (DC) is necessary to address various research questions, such as the role of DC subsets in immune-mediated diseases of horses. Unassigned: We applied single-cell RNA sequencing (scRNA-seq) on DC enriched from the blood of two horses. Unassigned: All main DC subsets were detected by key gene expression, including conventional DC type 1 (cDC1; ) and type 2 (cDC2; , ), as well as plasmacytoid DC (pDC; ). In addition, we detected a small cluster of hematopoietic progenitors, as well as transitional DC (tDC; , ) and putative DC type 3 (DC3; , ). Our...
