DNA research : an international journal for rapid publication of reports on genes and genomes.
Publisher:
Kazusa DNA Research Institute ;. Oxford : Oxford University Press (2006)
Frequency: Six no. a year
Country: England
Language: English
Author(s):
Kazusa Dī Enu Ē Kenkyūjo.
Start Year:1994 -
ISSN:
1340-2838 (Print)
1756-1663 (Electronic)
1340-2838 (Linking)
1756-1663 (Electronic)
1340-2838 (Linking)
Impact Factor
4.1
| NLM ID: | 9423827 |
| (DNLM): | SR0080606(s) |
| (OCoLC): | 30467755 |
| Coden: | DARSE8 |
| LCCN: | sn 94038370 |
| Classification: | W1 DN125G |
Peeling back the evolutionary layers of molecular mechanisms responsive to exercise-stress in the skeletal muscle of the racing horse. The modern horse (Equus caballus) is the product of over 50 million yrs of evolution. The athletic abilities of the horse have been enhanced during the past 6000 yrs under domestication. Therefore, the horse serves as a valuable model to understand the physiology and molecular mechanisms of adaptive responses to exercise. The structure and function of skeletal muscle show remarkable plasticity to the physical and metabolic challenges following exercise. Here, we reveal an evolutionary layer of responsiveness to exercise-stress in the skeletal muscle of the racing horse. We analysed differentia...
Characterization of equine microsatellites and microsatellite-linked repetitive elements (eMLREs) by efficient cloning and genotyping methods. We performed efficient cloning and genotyping methods for isolation of a large number of polymorphic microsatellites. The methods contain the time-efficient cloning method of constructing microsatellite-enriched libraries and the economic genotyping method of fluorescent labeling of PCR products. Eighty novel equine microsatellites cloned were efficiently isolated from the enrichment library and analyzed for genotype polymorphism. Of these, 72 microsatellites were analyzed with a good resolution. The average heterozygosity of all loci was 0.52, and the number of alleles ranged from one to 9 wi...