Haematologica.

Periodical
Hematology
Publisher:
Ferrata Storti Foundation. Pavia, Italy : Ferrata Storti Foundation (1999)
Frequency: Monthly, 1998-
Country: Italy
Language: Italian
Start Year:1920 -
ISSN:
0390-6078 (Print)
1592-8721 (Electronic)
0390-6078 (Linking)
Impact Factor
10.1
2022
NLM ID:0417435
(OCoLC):01118753
(DNLM):H00160000(s)
Coden:HAEMAX
LCCN:sn 83004856
Classification:W1 HA156
Efficacy of rabbit anti-thymocyte globulin in severe aplastic anemia.
Haematologica    May 23, 2011   Volume 96, Issue 9 1269-1275 doi: 10.3324/haematol.2011.042622
Afable MG, Shaik M, Sugimoto Y, Elson P, Clemente M, Makishima H, Sekeres MA, Lichtin A, Advani A, Kalaycio M, Tiu RV, O'Keefe CL, Maciejewski JP.A combination of horse anti-thymocyte globulin and cyclosporine produces responses in 60-70% of patients with severe aplastic anemia. We performed a phase II study of rabbit anti-thymocyte globulin and cyclosporine as first-line therapy for severe aplastic anemia. Methods: Twenty patients with severe aplastic anemia treated with rabbit anti-thymocyte globulin were compared to 67 historical control cases with matched clinical characteristics treated with horse anti-thymocyte globulin. Results: Response rates at 3, 6 and 12 months were similar for patients treated with rabbit anti-thymocyte glob...
Paroxysmal nocturnal hemoglobinuria clones in severe aplastic anemia patients treated with horse anti-thymocyte globulin plus cyclosporine.
Haematologica    July 3, 2010   Volume 95, Issue 7 1075-1080 doi: 10.3324/haematol.2009.017889
Scheinberg P, Marte M, Nunez O, Young NS.Clones of glycosylphosphatidylinositol-anchor protein-deficient cells are characteristic in paroxysmal nocturnal hemoglobinuria and are present in about 40-50% of patients with severe aplastic anemia. Flow cytometry has allowed for sensitive and precise measurement of glycosylphosphatidylinositol-anchor protein-deficient red blood cells and neutrophils in severe aplastic anemia. Methods: We conducted a retrospective analysis of paroxysmal nocturnal hemoglobinuria clones measured by flow cytometry in 207 consecutive severe aplastic anemia patients who received immunosuppressive therapy with a h...