International journal of tissue reactions.
Discontinued
Publisher:
Bioscience Ediprint Inc.,
Frequency: Bimonthly
Country: Switzerland
Language: English
Start Year:1980 - 2005
Identifiers
| ISSN: | 0250-0868 (Print) 0250-0868 (Linking) |
| NLM ID: | 8302116 |
| (OCoLC): | 08994929 |
| (DNLM): | I28245500(s) |
| LCCN: | sc 84008549 |
| Classification: | W1 IN797B |
Influence of an epidermal cell extract on skin healing and scar formation. We have examined the possible regulatory role of epidermal cell extract(s) (ECE) on skin cells, namely fibroblasts and keratinocytes, both in vivo and in vitro with particular reference to modification of scar formation. In an experimental wound model in pigs, it was found that extracts of cultured human and pig keratinocytes stimulated replication of epidermal cells and their migration from wound edges and remnants of hair follicles and sebaceous glands, together with hair growth, but at the same time suppressed fibroblast proliferation in the dermis. Sections of healing skin wounds that had ...