The Journal of biological chemistry.
Periodical
Biochemistry
Publisher:
American Society for Biochemistry and Molecular Biology. [New York, NY] : Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology (2021)
Frequency: Weekly, 1994-
Country: United States
Language: English
Author(s):
American Society of Biological Chemists., American Society of Biological Chemists., Rockefeller Institute for Medical Research.
Start Year:1905 -
ISSN:
0021-9258 (Print)
1083-351X (Electronic)
1067-8816 (Undetermined)
0021-9258 (Linking)
1083-351X (Electronic)
1067-8816 (Undetermined)
0021-9258 (Linking)
Impact Factor
5.5
2022
| NLM ID: | 341041 |
| (DNLM): | J14380000(s) |
| (OCoLC): | 01782222 |
| Coden: | JBCHA3 |
| LCCN: | 06046735 |
| Classification: | W1 JO564C |
Interconversion of horse heart cytochrome C monomer and polymers.
The Journal of biological chemistry
November 1, 1962
Volume 237 3397-3405
MARGOLIASH E, LUSTGARTEN J.No abstract available Read More
32
Metallothionein: a cadmium and zinc-containign protein from equine renal cortex. II. Physico-chemical properties.
The Journal of biological chemistry
September 1, 1961
Volume 236 2435-2442
KAGI JH, VALLEE BL.No abstract available Read More
113
Metallothionein: a cadmium- and zinc-containing protein from equine renal cortex.
The Journal of biological chemistry
December 1, 1960
Volume 235 3460-3465
KAGI JH, VALEE BL.No abstract available Read More
141
Biosynthesis of estrogen by the perfused stallion testis.
The Journal of biological chemistry
January 1, 1959
Volume 234, Issue 1 16-18
NYMAN MA, GEIGER J, GOLDZIEHER JW.No abstract available The biosynthesis of estrone and progesterone in the pregnant mare.
The Journal of biological chemistry
April 1, 1958
Volume 231, Issue 2 765-776
SAVARD K, ANDREC K, BROOKSBANK BW, REYNERI C, DORFMAN RI.No abstract available Zinc in horse liver alcohol dehvdrogenase.
The Journal of biological chemistry
March 1, 1957
Volume 225, Issue 1 185-195
VALLEE BL, HOCH FL.No abstract available Read More
13
Free amino groups of equine gamma-globulins and a specific antibody.
The Journal of biological chemistry
October 1, 1955
Volume 216, Issue 2 621-624
MCFADDEN ML, SMITH EL.No abstract available Masking of acid-binding groups in native horse carbonylhemoglobin.
The Journal of biological chemistry
May 1, 1951
Volume 190, Issue 1 197-210
STEINHARDT J, ZAISER EM.No abstract available The configuration of the allopregnanetriol-3,16,20 of the urine of pregnant mares.
The Journal of biological chemistry
April 1, 1949
Volume 178, Issue 2 751-774
HIRSCHMANN H, HIRSCHMANN FB, DAUS MA.No abstract available The occurrence of alpha-estradiol in the urine of stallions; its identification and isolation.
The Journal of biological chemistry
March 1, 1949
Volume 178, Issue 1 229-240
LEVIN L.No abstract available Biophysical studies of blood plasma proteins; fractionation studies of normal and immune horse serum.
The Journal of biological chemistry
November 1, 1948
Volume 176, Issue 2 797-812
DEUTSCH HF, NICHOL JC.No abstract available The isolation and properties of the proteins associated with tetanus antitoxic activity in equine plasma.
The Journal of biological chemistry
March 1, 1947
Volume 167, Issue 3 679-687
SMITH EL, GERLOUGH TD.No abstract available Metallothionein: a cadmium- and zinc-containing protein from equine renal cortex.
The Journal of biological chemistry
December 1, 1960
Volume 235 3460-3465
KAGI JH, VALEE BL.No abstract available Read More
141
Metallothionein: a cadmium and zinc-containign protein from equine renal cortex. II. Physico-chemical properties.
The Journal of biological chemistry
September 1, 1961
Volume 236 2435-2442
KAGI JH, VALLEE BL.No abstract available Read More
113
A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis.
The Journal of biological chemistry
April 11, 1997
Volume 272, Issue 15 9621-9624 doi: 10.1074/jbc.272.15.9621
Hu S, Vincenz C, Buller M, Dixit VM.Molluscum contagiosum virus proteins MC159 and MC160 and the equine herpesvirus 2 protein E8 share substantial homology to the death effector domain present in the adaptor molecule Fas-associated death domain protein (FADD) and the initiating death protease FADD-like interleukin-1beta-converting enzyme (FLICE) (caspase-8). FADD and FLICE participate in generating the death signal from both tumor necrosis factor receptor-1 (TNFR-1) and the CD-95 receptor. The flow of death signals from TNFR-1 occurs through the adaptor molecule tumor necrosis factor receptor-associated death domain protein (TRA... Read More
80
Antigenic variation during persistent infection by equine infectious anemia virus, a retrovirus.
The Journal of biological chemistry
August 25, 1984
Volume 259, Issue 16 10539-10544
Montelaro RC, Parekh B, Orrego A, Issel CJ.The recurrent nature of equine infectious anemia has been attributed to relatively rapid antigenic variations in equine infectious anemia virus (EIAV) during persistent infection under selective immune pressures. This model was tested by serological and biochemical analysis of virus isolates recovered from separate febrile episodes in two experimentally infected ponies. Neutralization assays employing immune sera from the experimentally infected ponies demonstrated that distinct antigenic strains of virus predominate during sequential febrile episodes in a single pony. Analysis of the test str... Read More
75
Aspartic acid racemization and collagen degradation markers reveal an accumulation of damage in tendon collagen that is enhanced with aging.
The Journal of biological chemistry
March 22, 2010
Volume 285, Issue 21 15674-15681 doi: 10.1074/jbc.M109.077503
Thorpe CT, Streeter I, Pinchbeck GL, Goodship AE, Clegg PD, Birch HL.Little is known about the rate at which protein turnover occurs in living tendon and whether the rate differs between tendons with different physiological roles. In this study, we have quantified the racemization of aspartic acid to calculate the age of the collagenous and non-collagenous components of the high strain injury-prone superficial digital flexor tendon (SDFT) and low strain rarely injured common digital extensor tendon (CDET) in a group of horses with a wide age range. In addition, the turnover of collagen was assessed indirectly by measuring the levels of collagen degradation mark... Read More
69
Equine hepatic and renal metallothioneins. Purification, molecular weight, amino acid composition, and metal content.
The Journal of biological chemistry
June 10, 1974
Volume 249, Issue 11 3537-3542
Kägi JH, Himmelhoch SR, Whanger PD, Bethune JL, Vallee BL.No abstract available Read More
58
Proteomic analysis reveals age-related changes in tendon matrix composition, with age- and injury-specific matrix fragmentation.
The Journal of biological chemistry
July 30, 2014
Volume 289, Issue 37 25867-25878 doi: 10.1074/jbc.M114.566554
Peffers MJ, Thorpe CT, Collins JA, Eong R, Wei TK, Screen HR, Clegg PD.Energy storing tendons, such as the human Achilles and equine superficial digital flexor tendon (SDFT), are highly prone to injury, the incidence of which increases with aging. The cellular and molecular mechanisms that result in increased injury in aged tendons are not well established but are thought to result in altered matrix turnover. However, little attempt has been made to fully characterize the tendon proteome nor determine how the abundance of specific tendon proteins changes with aging and/or injury. The aim of this study was, therefore, to assess the protein profile of normal SDFTs ... Read More
50
The concentrations of free Mg2+ and free Zn2+ in equine blood plasma.
The Journal of biological chemistry
August 15, 1987
Volume 262, Issue 23 11140-11148
Magneson GR, Puvathingal JM, Ray WJ.The enzyme phosphoglucomutase can be used as a metal ion indicator to measure the concentrations of free Mg2+ and free Zn2+ in physiological fluids. In horse plasma, the concentration of free Mg2+ is close to 0.5 mM, whereas that of free Zn2+ is about 2 X 10(-10) M, although numerous physiological roles for Zn2+ have been postulated that would require free Zn2+ concentration orders of magnitude higher than this. A titration of plasma with Zn2+ shows that the fractional increase in free Zn2+ is essentially the same as the fractional increase in total exchangeable Zn2+, and the results are consi... Read More
48
Interconversion of horse heart cytochrome C monomer and polymers.
The Journal of biological chemistry
November 1, 1962
Volume 237 3397-3405
MARGOLIASH E, LUSTGARTEN J.No abstract available Read More
32
Mechanisms of the reactions of cytochrome c. Rate and equilibrium constants for ligand binding to horse heart ferricytochrome c.
The Journal of biological chemistry
November 10, 1972
Volume 247, Issue 21 6932-6936
Sutin N, Yandell JK.No abstract available Read More
28
The equilibrium unfolding parameters of horse and sperm whale myoglobin. Effects of guanidine hydrochloride, urea, and acid.
The Journal of biological chemistry
July 10, 1973
Volume 248, Issue 13 4623-4634
Puett D.No abstract available Read More
28
cDNA cloning and sequencing reveal the major horse allergen Equ c1 to be a glycoprotein member of the lipocalin superfamily.
The Journal of biological chemistry
December 20, 1996
Volume 271, Issue 51 32951-32959 doi: 10.1074/jbc.271.51.32951
Gregoire C, Rosinski-Chupin I, Rabillon J, Alzari PM, David B, Dandeu JP.The gene encoding the major horse allergen, designated Equus caballus allergen 1 (Equ c1), was cloned from total cDNA of sublingual salivary glands by reverse transcription-polymerase chain reaction using synthetic degenerate oligonucleotides deduced from N-terminal and internal peptide sequences of the glycosylated hair dandruff protein. A recombinant form of the protein, with a polyhistidine tail, was expressed in Escherichia coli and purified by immobilized metal affinity chromatography. The recombinant protein is able to induce a passive cutaneous anaphylaxis reaction in rat, and it behave... Read More
23
Fibronectin mRNA splice variant in articular cartilage lacks bases encoding the V, III-15, and I-10 protein segments.
The Journal of biological chemistry
August 2, 1996
Volume 271, Issue 31 18954-18960 doi: 10.1074/jbc.271.31.18954
MacLeod JN, Burton-Wurster N, Gu DN, Lust G.Fibronectin is an extracellular matrix glycoprotein encoded by a single gene. Alternative RNA splicing has been reported at three sites, ED (extra type III domain)-A, ED-B, and the variable or V region. Articular cartilage fibronectin monomers are rarely (ED-A)+, but approximately 25% are (ED-B)+. RNA gel electrophoresis and Northern blot analysis identified two (ED-B)+ and two (ED-B)- fibronectin transcripts in cartilage, each pair differing by approximately 750 bases. This difference results from a previously unreported RNA splicing pattern that eliminates not only the V region but also nucl... Read More
22
Does the cytotoxic effect of transient amyloid oligomers from common equine lysozyme in vitro imply innate amyloid toxicity?
The Journal of biological chemistry
December 1, 2004
Volume 280, Issue 8 6269-6275 doi: 10.1074/jbc.M407273200
Malisauskas M, Ostman J, Darinskas A, Zamotin V, Liutkevicius E, Lundgren E, Morozova-Roche LA.In amyloid diseases, it is not evident which protein aggregates induce cell death via specific molecular mechanisms and which cause damage because of their mass accumulation and mechanical properties. We showed that equine lysozyme assembles into soluble amyloid oligomers and protofilaments at pH 2.0 and 4.5, 57 degrees C. They bind thioflavin-T and Congo red similar to common amyloid structures, and their morphology was monitored by atomic force microscopy. Molecular volume evaluation from microscopic measurements allowed us to identify distinct types of oligomers, ranging from tetramer to oc... Read More
21
A novel lipoarabinomannan from the equine pathogen Rhodococcus equi. Structure and effect on macrophage cytokine production.
The Journal of biological chemistry
June 18, 2002
Volume 277, Issue 35 31722-31733 doi: 10.1074/jbc.M203008200
Garton NJ, Gilleron M, Brando T, Dan HH, Giguère S, Puzo G, Prescott JF, Sutcliffe IC.Rhodococcus equi is a major cause of foal morbidity and mortality. We have investigated the presence of lipoglycan in this organism as closely related bacteria, notably Mycobacterium tuberculosis, produce lipoarabinomannans (LAM) that may play multiple roles as virulence determinants. The lipoglycan was structurally characterized by gas chromatography-mass spectrometry following permethylation, capillary electrophoresis after chemical degradation, and (1)H and (31)P and two-dimensional heteronuclear nuclear magnetic resonance studies. Key structural features of the lipoglycan are a linear alph... Read More
19
The interaction of equine platelet tropomyosin with skeletal muscle actin.
The Journal of biological chemistry
July 25, 1981
Volume 256, Issue 14 7257-7261
Côté GP, Smillie LB.Whereas skeletal muscle tropomyosin binds strongly to muscle F-actin in a buffer containing 30 mM KCl and 1-2 mM free Mg2+, equine platelet tropomyosin only binds stoichiometrically (1 tropomyosin molecule per 6 actin monomers) at higher Mg2+ concentrations (7-8 mM free Mg2+). At low free Mg2+ concentrations (1.5 mM) the binding of the platelet protein is only marginally increased by raising the KCl concentration to an optimal value (0.10-0.20 M). This weaker binding can be attributed to the relatively poor head-to-tail polymerization of platelet tropomyosin and its fewer actin-binding sites. ... Read More
19
Proteomic analysis of tendon extracellular matrix reveals disease stage-specific fragmentation and differential cleavage of COMP (cartilage oligomeric matrix protein).
The Journal of biological chemistry
January 7, 2014
Volume 289, Issue 8 4919-4927 doi: 10.1074/jbc.M113.511972
Dakin SG, Smith RK, Heinegård D, Önnerfjord P, Khabut A, Dudhia J.During inflammatory processes the extracellular matrix (ECM) is extensively remodeled, and many of the constituent components are released as proteolytically cleaved fragments. These degradative processes are better documented for inflammatory joint diseases than tendinopathy even though the pathogenesis has many similarities. The aims of this study were to investigate the proteomic composition of injured tendons during early and late disease stages to identify disease-specific cleavage patterns of the ECM protein cartilage oligomeric matrix protein (COMP). In addition to characterizing fragme... Read More
19
Platelet-activating factor stimulates the phosphatidylinositol cycle. Appearance of phosphatidic acid is associated with the release of serotonin in horse platelets.
The Journal of biological chemistry
July 10, 1982
Volume 257, Issue 13 7314-7317
Lapetina EG.The addition of platelet-activating factor to horse platelets prelabeled with (32P)orthophosphate induces the rapid formation of [32P]phosphatidic acid. This is subsequently followed by a considerable increase in the labeling of phosphatidylinositol. Activation of the formation of phosphatidic acid by platelet-activating factor is evident at a concentration of 1 nM, is maximal at 0.1 microM, and independent of the presence or absence of plasma in the medium. In horse platelets prelabeled with [14C]arachidonic acid, platelet-activating factor stimulates the rapid formation of [14C]phosphatidic ... Read More
18
Structure of dermatan sulfate. VII. The copolymeric structure of dermatan sulfate from horse aorta.
The Journal of biological chemistry
September 25, 1970
Volume 245, Issue 18 4770-4783
Fransson LA, Havsmark B.The structure of dermatan sulfate-chondroitin sulfate
copolymers, isolated from horse aorta, has been examined.
It was found that a large proportion of the galactosaminoglycans of this tissue was obtained as a discrete polysaccharide fraction with an L-iduronic acid to D-glucuronic
acid ratio of approximately 1: 2. This finding together with
infrared data indicated that the polymer contained approximately equimolar proportions of the three repeating disaccharide units glucuronosyl-N-acetylgalactosamine 4-sulfate
(A), iduronosyl-N-acetylgalactosamine 4-sulfate (B), and
glucuronosyl-N-acet... Read More
16
Steady state kinetics and binding of eukaryotic cytochromes c with yeast cytochrome c peroxidase.
The Journal of biological chemistry
February 10, 1977
Volume 252, Issue 3 919-926
Kang CH, Ferguson-Miller S, Margoliash E.1. The steady state kinetics for the oxidation of ferrocytochrome c by yeast cytochrome c peroxidase are biphasic under most conditions. The same biphasic kinetics were observed for yeast iso-1, yeast iso-2, horse, tuna, and cicada cytochromes c. On changing ionic strength, buffer anions, and pH, the apparent Km values for the initial phase (Km1) varied relatively little while the corresponding apparent maximal velocities varied over a much larger range. 2. The highest apparent Vmax1 for horse cytochrome c is attained at relatively low pH (congruent to 6.0) and low ionic strength (congruent to... Read More
15
The subunit structure of horse spleen apoferritin. I. The molecular weight of the subunit.
The Journal of biological chemistry
July 10, 1971
Volume 246, Issue 13 4198-4205
Bryce CF, Crichton RR.No abstract available Read More
15
Equine lutropin and chorionic gonadotropin bear oligosaccharides terminating with SO4-4-GalNAc and Sia alpha 2,3Gal, respectively.
The Journal of biological chemistry
January 15, 1993
Volume 268, Issue 2 795-802
Smith PL, Bousfield GR, Kumar S, Fiete D, Baenziger JU.Equine chorionic gonadotropin (eCG) and lutropin (eLH) are heterodimeric glycoprotein hormones which are synthesized in the placenta and pituitary, respectively. The beta subunits of eCG and eLH, like their alpha subunits, arise from a single gene and have identical amino acid sequences. In contrast, the beta subunits of CG and LH in primates arise from different genes and differ in sequence. We have examined the structures of the Asn-linked oligosaccharides on eCG and eLH. eCG bears di- and tri-branched Asn-linked oligosaccharides terminating with Sia alpha 2,3 or 6Gal beta 1,4GlcNAc. In cont... Read More
15
Structural studies on equine glycoprotein hormones. Amino acid sequence of equine chorionic gonadotropin beta-subunit.
The Journal of biological chemistry
June 25, 1987
Volume 262, Issue 18 8603-8609
Sugino H, Bousfield GR, Moore WT, Ward DN.The complete amino acid sequence of the beta-subunit of equine chorionic gonadotropin (eCG beta) has been established by both automated Edman and manual 5-dimethylaminonaphthalene-1-sulfonyl-Edman degradations. Specific fragments were produced by cleavage with Staphylococcus aureus V8 protease, trypsin, or dilute HCl. For the sequence analyses of the heavily glycosylated COOH-terminal portion, a chemical deglycosylation procedure with trifluoromethanesulfonic acid was employed. The peptide chain of eCG beta consists of 149 amino acid residues. Five or more oligosaccharide chains are attached t... Read More
14
Zinc in horse liver alcohol dehvdrogenase.
The Journal of biological chemistry
March 1, 1957
Volume 225, Issue 1 185-195
VALLEE BL, HOCH FL.No abstract available Read More
13
Electrophoretic behavior of mammalian-type cytochromes c.
The Journal of biological chemistry
April 10, 1966
Volume 241, Issue 7 1473-1477
Barlow GH, Margoliash E.No abstract available Read More
13
Demonstration of a COOH-terminal extension on equine lutropin by means of a common acid-labile bond in equine lutropin and equine chorionic gonadotropin.
The Journal of biological chemistry
August 15, 1985
Volume 260, Issue 17 9531-9533
Bousfield GR, Sugino H, Ward DN.The beta subunits of equine lutropin and equine chorionic gonadotropin were incubated in 0.013 N HCl for 30 min at 110 degrees C and separated into two fragments by reverse-phase high performance liquid chromatography. The amino acid and carbohydrate compositions of both fragments from each subunit were analyzed. The results demonstrated that equine lutropin-beta has a glycosylated COOH-terminal extension that differs only in carbohydrate composition from the COOH-terminal portion of equine chorionic gonadotropin-beta. This is the first demonstration of a glycosylated COOH-terminal extension i... Read More
13
Microheterogeneity of type II cAMP-dependent protein kinase in various mammalian species and tissues.
The Journal of biological chemistry
August 25, 1984
Volume 259, Issue 16 10596-10605
Robinson-Steiner AM, Beebe SJ, Rannels SR, Corbin JD.Excluding autophosphorylated species, at least six forms of the regulatory subunit of type II cAMP-dependent protein kinase (RII) from various mammalian tissues were identified by sodium dodecyl sulfate (SDS) gel electrophoresis of purified samples and of crude preparations photoaffinity labeled with 8-azido[32P] cAMP and by gel filtration. After autophosphorylation some heart RII forms termed type IIA (bovine, porcine, equine, and dog) shifted to a more slowly migrating band on SDS gels while others termed type IIB (rat, guinea pig, rabbit, and monkey) did not detectably shift. Both subclasse... Read More
13
Microvesicle-mediated Wnt/β-Catenin Signaling Promotes Interspecies Mammary Stem/Progenitor Cell Growth.
The Journal of biological chemistry
October 12, 2016
Volume 291, Issue 47 24390-24405 doi: 10.1074/jbc.M116.726117
Bussche L, Rauner G, Antonyak M, Syracuse B, McDowell M, Brown AMC, Cerione RA, Van de Walle GR.Signaling mechanisms that regulate mammary stem/progenitor cell (MaSC) self-renewal are essential for developmental changes that occur in the mammary gland during pregnancy, lactation, and involution. We observed that equine MaSCs (eMaSCs) maintain their growth potential in culture for an indefinite period, whereas canine MaSCs (cMaSCs) lose their growth potential in long term cultures. We then used this system to investigate the role of microvesicles (MVs) in promoting self-renewal properties. We found that Wnt3a and Wnt1 were expressed at higher levels in MVs isolated from eMaSCs compared wi... Read More
12
Further study of the chemical structure of the equine erythrocyte hematoside containing O-acetyl ester.
The Journal of biological chemistry
January 25, 1983
Volume 258, Issue 2 876-881
Gasa S, Makita A, Kinoshita Y.The chemical structure of an equine hematoside, which contained an ester group and comprised 72% of the total erythrocyte gangliosides, was determined by means of nondestructive and destructive procedures. A 400-MHz nuclear magnetic resonance spectrum of the ganglioside in perdeuterodimethyl sulfoxide demonstrated three protons due to a methyl group of an acetyl moiety, as well as amide and anomeric protons which were compatible with those of the ordinary hematoside. The spin decoupling difference spectroscopy of the ganglioside revealed the presence of the following structures. [formula: see ... Read More
12
Identification of a major iodolipid from the horse thyroid gland as 2-iodohexadecanal.
The Journal of biological chemistry
October 5, 1990
Volume 265, Issue 28 17018-17025
Pereira A, Braekman JC, Dumont JE, Boeynaems JM.The incorporation of iodide into proteins (PBI) and lipids (LBI) of horse thyroid slices was measured in various conditions. Their dependency on the concentration of extracellular iodide was strikingly different. For PBI the relationship was biphasic with a decrease above 10 microM, likely to correspond to the Wolff-Chaikoff effect. On the contrary, LBI increased as a function of iodide concentration up to 100 microM. Methimazole (MMI) inhibited the incorporation of iodide into both LBI and PBI, but higher concentrations of MMI were required to depress LBI as compared to PBI. The inhibition of... Read More
11